Surface patterning manufacturing method of biological protein film

Abstract

The invention discloses a surface patterning manufacturing method of a biological protein film. The method comprises the following steps: S1, preparing a metamaterial array; S2, preparing a biologicalprotein film; S3, enabling the metamaterial array to be in contact with the biological protein film, and radiating the metamaterial array through electromagnetic waves; S4, moving the biological protein film, and performing pattern direct writing on the surface of the biological protein film; and S5, developing the biological protein film through a developing solution. According to the invention,a mask plate is not needed, the bioprotein film can be directly processed through the metamaterial array, and the operation is simple and convenient; the resolution of the biological protein film subjected to pattern direct writing is related to the gap size of the metamaterial array, the nanoscale resolution can be achieved, and the resolution is high; the metamaterial array is provided with a plurality of element structures, and the element structures can be used as photoetching direct writing heads, so that the plurality of photoetching direct writing heads can work synchronously, and thedirect writing efficiency is higher.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a method for patterning the surface of a biological protein film. Background technique [0002] Protein is the smallest active unit that constitutes a living body, that is, the most basic form of life. In different stages of life development, the types and compositions of proteins are different; in different tissues, the proteins expressed by cells vary greatly. A gene is the functional unit of heredity that instructs the synthesis of proteins. Gene mutation, its expression product - protein must be abnormal accordingly, the occurrence and development of any disease will first be expressed at the protein level. Therefore, exploring the laws of life activities at the protein level and studying the mechanism of disease occurrence are of great significance not only for the understanding of life phenomena, but also for the early and accurate diagnosis of diseases. [0003] For some bi...

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Problems solved by technology

However, the methods for patterning biological proteins by the above methods have not been reported yet.

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