Preparation for treating degenerative disc diseases and preparation method thereof

Abstract

The invention relates to the technical field of lumbar intervertebral disc medical treatment, in particular to a preparation for treating degenerative disc diseases and a preparation method. The preparation for treating the degenerative disc diseases comprises mesenchymal stem cells, and the mesenchymal stem cells are induced and cultured by a conditional culture medium of chondrocytes, so that the differentiation of the mesenchymal stem cells is facilitated; and the mesenchymal stem cells are wrapped with hydrogel, and the survival rate and activity of the mesenchymal stem cells in the body are enhanced. The invention also provides a heat preservation injector used for the preparation for treating degenerative disc diseases, and the tube wall of the heat preservation injector is filled with a heat preservation material, so that the temperature of contents is ensured, the activity of cells is favorably maintained, and the stress reaction of an organism is reduced.

Description

technical field [0001] The invention relates to the technical field of lumbar intervertebral disc medical treatment, in particular to a preparation and a preparation method for treating lumbar intervertebral disc degenerative disease. Background technique [0002] Low back pain (LBP) is considered the leading cause of disability worldwide, affecting approximately 632 million people worldwide. Although the direct cause of LBP is unknown, its symptoms are related to the degeneration and deformation of the lumbar intervertebral disc (IVD). A lumbar disc is a fibrocartilaginous tissue structure between two vertebrae. Lumbar disc herniation is one of the more common diseases, mainly because various parts of the lumbar intervertebral disc (nucleus pulposus, annulus fibrosus and cartilage plate), especially the nucleus pulposus, have degenerative changes to varying degrees, and under the action of external forces , the annulus fibrosus of the intervertebral disc ruptures, and the...

AI Technical Summary

Problems solved by technology

Due to the limitation of the special physiological position of the lumbar spine, the operation destroys the normal physiological structure of the lumbar spine, resulting in large surgical injuries, easy to cause postoperative instability of the lumbar spine, postoperative scar tissue adhesion, and a series of adverse reactions such as accidental nerve root injury during the operation;

[0009] 6. Minimally invasive surgery of intervertebral discs avoids the large damage caused by conventional open surgery, reduces the risk of surgery and the occurrence of complications. In microsurgery and arthroscopic assisted lumbar intervertebral disc surgery, although it reduces the risk of damage during the operation. Destruction of normal bones and joints, but after the surgical field of view becomes smaller, it is difficult to clean and completely remove the diseased lumbar disc nucleus pulposus, which increases the risk of unsuccessful surgery;

Theoretically, injecting ozone can gasify and concentrate the nucleus pulposus of the lumbar intervertebral disc, but what chemical reactions and complications will occur when ozone enters the spinal canal needs further observation and research. According to current patient feedback, the success rate of this treatment method is not high. too high

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