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Method for improving fat filling effect of face and other parts by using adipose-derived stem cells

An adipose stem cell and fat cell technology, applied in the application field of autologous fat stem cells, can solve the problem of low survival rate of fat cells, achieve good filling effect, reduce fat hyperplasia, and reduce fat particles.

Pending Publication Date: 2020-04-28
张亚楠
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Problems solved by technology

[0004] Aiming at the existing problems of a certain degree of absorption rate and low survival rate of fat cells after using autologous fat for facial filling transplantation, the present invention provides a method for improving the effect of fat filling on the face and other parts by using autologous fat stem cells, which mainly includes The extraction of fat and the extraction and concentration of ADSCs and adipocytes, the extraction of the fat can be based on the subjective requirements of the experimenter and their own conditions, select the upper arm, abdomen and inner and outer thighs as donor sites and mark them, the ADSCs and adipocytes The extraction and concentration are mainly divided into the following steps:

Method used

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  • Method for improving fat filling effect of face and other parts by using adipose-derived stem cells
  • Method for improving fat filling effect of face and other parts by using adipose-derived stem cells
  • Method for improving fat filling effect of face and other parts by using adipose-derived stem cells

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specific Embodiment 1

[0024] Concrete embodiment 1: in order to illustrate whether controlling ADSCs is true and effective in conjunction with ADSCs assisted fat transplantation technology in the time of external processing, this method has been applied in the early stage to carry out BALB / c nude mouse animal model test, observes experimental result, finds that adopts the fat of control time Stem cell-assisted fat particle transplantation can effectively improve the survival rate of fat cells after fat transplantation. The specific implementation steps are as follows:

[0025] 1. The first is the acquisition of ADSCs and fat cells, as follows:

[0026] 1.1 Fat extraction: According to the subjective requirements of the experimenter and their own conditions, the upper arm, abdomen, and inner and outer thighs were selected as the donor area and the range of fat extraction was marked. The specific operation is as follows: In the conventional tumescent anesthesia at the donor site, use 500 ml of 0.9% n...

specific Embodiment 2

[0042] Specific embodiment 2: in order to solve because there is a certain degree of absorption rate after autologous fat transplantation, by clinical observation, according to experimenter's age, transplantation site, transplantation volume and individual difference, autologous fat absorption rate is about 30%~90%, average More than 60% of this problem. After submitting to the clinical committee for approval and signing an informed and waiver agreement with the experimenter, the present invention applied this method to the experimenter, and found that by shortening the in vitro treatment time from ADSCs (currently the shortest in vitro treatment time is 40 minutes), it can effectively improve fat Survival rate after transplantation, increase experimenter's satisfaction. Its specific implementation steps are as follows:

[0043] one. Procurement of self-derived ADSCs and adipocytes

[0044] 1.1. Autologous fat extraction: According to the subjective requirements of the expe...

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Abstract

The invention relates to the application field of adipose-derived stem cells, and in particular to a method for improving fat filling effect of face and other parts by using adipose-derived stem cells(ADSCs). The method mainly comprises extraction of fat and extraction and concentration of ADSCs and adipose cells, wherein the extraction of fat can be performed by selecting upper arms, abdomen, inner sides and outer sides of thighs as supply areas and marking according to subjective requirements and self conditions of experimenters. By controlling in-vitro treatment time of the ADSCs and combining with ASCs assisted fat transplantation technology, the method improves survival rate of transplanted fat cells on face, effectively improves user satisfaction after facial filling, and reduces morbidity of fat transplantation complications and sequelae.

Description

technical field [0001] The invention relates to the application field of autologous fat stem cells, in particular to a method for improving the effect of fat filling on the face and other parts by using autologous fat stem cells. Background technique [0002] Whether the facial contour is clear and plump, in addition to skeletal factors, is mainly determined by facial subcutaneous fat. Generally speaking, facial subcutaneous fat is plump in adolescents to middle-aged people. However, with age or due to certain diseases or trauma, facial subcutaneous fat Reduced, it will appear thinner and sunken, younger facial tissue with age, will also produce skin relaxation, subcutaneous collagen reduction, fat particle reduction, fascia relaxation, muscle volume reduction and elasticity reduction, etc. The reduction of soft tissue volume will As a result, the bones appear, and the face shape changes from the "goose egg-like shape" in youth to "diamond-like shape". Due to the reduction a...

Claims

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Application Information

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IPC IPC(8): A61L27/38A61L27/36
CPCA61L27/3604A61L27/3687A61L27/3691A61L27/3834A61L2430/34
Inventor 张亚楠
Owner 张亚楠
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