A kind of sweetener and preparation method thereof
A sweetener, natural technology, applied in the preparation of sugar derivatives, chemical instruments and methods, food science and other directions, can solve the problems of increasing the cost of food processing, large dosage, etc., to promote the differentiation of fat cells, improve sweetness, The effect of reducing the amount of addition
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Embodiment 1
[0025] A sweetener proposed by the present invention adopts glucobiose whose natural trehalose structure is α, α, 1, 1-docking; the 2-hydroxyl of the two glucose residues of natural trehalose is replaced by a chlorine atom, and the configuration Simultaneously flip to S-configuration; the 6-hydroxyl on one of the two glucose residues is replaced by a chlorine atom;
[0026] Its chemical structural formula is:
[0027]
[0028] In the present invention, the sweetness test of the sweetener is superior to granulated sugar and trehalose, which are respectively 75 times that of granulated sugar and 167 times that of trehalose. The sweetener has the advantages of improving sweetness, reducing the amount of added sugar in food, and not promoting obesity. , can be widely used as sweet additives in food and beverages, etc., healthy and safe to eat.
Embodiment 2
[0030] The present invention also proposes the preparation method about above-mentioned sweetener, and its preparation method comprises the following steps:
[0031] Dissolve the natural trehalose structure of α,α,1,1-docked glucobiose in anhydrous dimethylformamide DMF, add 30 equivalents of triethylamine Et 3 Then add 2.5 equivalents of recrystallized trityl chloride TrCl, and react at room temperature for 1-4 hours;
[0032] Then add tributylchlorosilane TBSCl to the reaction solution, continue to react at room temperature for 1-4 hours, then pour into the water phase, extract with ethyl acetate, and the product can be processed in the ethyl acetate-methyl tert-butyl ether MTBE system for several times. Purified by recrystallization to obtain compound A.
[0033] Among them, the characteristics of compound A 13 C NMR data are as follows (unit: ppm): 18.4, 25.9, 64.5, 70.0, 71.8, 74.4, 77.2, 86.8, 100.0, 126.2, 128.2, 129.2, 143.9.
[0034] Dissolve compound A in dichloro...
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