Visual prosthesis microelectrode array capable of generating converged virtual electrodes

A micro-electrode array and virtual electrode technology, applied in the field of biomedicine, can solve the problems of low resolution, low visual acuity, and the inability to increase phantreal viewpoints, and achieve the effect of increasing the number of sensing sites and increasing the perceived visual acuity

Pending Publication Date: 2020-06-02
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, three visual prostheses have been approved for clinical application in the world, but due to the limitations of surgical safety and electrode manufacturing technology, visual prosthesis implanters can only obtain discrete low-resolution and low visual acuity visual perception
The existing technology

Method used

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  • Visual prosthesis microelectrode array capable of generating converged virtual electrodes
  • Visual prosthesis microelectrode array capable of generating converged virtual electrodes
  • Visual prosthesis microelectrode array capable of generating converged virtual electrodes

Examples

Experimental program
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Embodiment Construction

[0026] like figure 1 As shown, in this embodiment, the micro-electrode array 1 is implanted in the vitreous body 7 and fixed on the retina 6, and the micro-current stimulator 4 transmits the external stimulation signal received to the micro-electrode array 1 through the lead wire 5, and adjusts two adjacent electrodes. The stimulation current ratio of four ring electrodes makes the virtual electrode move in one dimension. By adjusting the stimulation current ratio of four adjacent ring electrodes, the virtual electrode can move in the two-dimensional area, thereby adjusting the stimulation position of the virtual electrode. point, the retina 6 is stimulated by the microelectrode array 1, and the retina 6 transmits the external electrical stimulation received to the visual cortex to form artificial visual perception.

[0027] The microelectrode array 1 is fixed on the macular area of ​​the retina 6 .

[0028] like figure 2 As shown, the microelectrode array 1 includes: a plu...

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Abstract

The invention discloses a visual prosthesis microelectrode array capable of generating converged virtual electrodes. The visual prosthesis microelectrode array comprises a microelectrode array, a common recovery electrode and a micro-current stimulator, wherein the micro-current stimulator stimulates adjacent ring electrodes in the microelectrode array according to a received external stimulationsignal; the microelectrode array is combined with the far-end common recovery electrode to generate virtual electrodes; the virtual electrodes move in a one-dimensional direction by adjusting the stimulation current proportion of two adjacent ring electrodes; and the virtual electrodes move in a two-dimensional region and converged virtual electrode stimulation is realized by adjusting the stimulation current proportion of four adjacent electrodes. According to the visual prosthesis microelectrode array, stimulation sites of the converged virtual electrodes can be adjusted, so that local virtual electrode stimulation of a retina is realized, the number of perception sites of a visual prosthesis implant is increased, and the perception visual sensitivity of the visual prosthesis implant isimproved. In addition, by disk electrodes, local physical electrode stimulation can further be realized, and the original physical electrode stimulation sites can be reserved while virtual electrode stimulation is carried out.

Description

technical field [0001] The invention relates to a technique in the field of biomedicine, in particular to a visual prosthetic microelectrode array capable of producing converging virtual electrodes. Background technique [0002] Retinal degeneration is an irreversible degenerative disease that causes blindness. Clinical acute electrophysiological studies have shown that patients with such diseases can perceive phosphenes after electrical stimulation. At present, three visual prostheses have been approved for clinical application in the world. However, due to the limitations of surgical safety and electrode manufacturing technology, visual prosthesis implanters can only obtain discrete low-resolution and low visual acuity visual perception. Existing technologies use image processing strategies or high-density microelectrode array stimulation, but the image processing strategy cannot add additional phosphene viewpoints. High-density microelectrode array stimulation methods st...

Claims

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Application Information

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IPC IPC(8): A61N1/05A61N1/36
CPCA61N1/0543A61N1/36046
Inventor 柴新禹芦卓凡李恒
Owner SHANGHAI JIAO TONG UNIV
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