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Protein-dense nutritional compositions for use in treating and/or preventing condition linked to loss of muscle mass and/or strength

A muscle mass, protein technology, applied in the treatment and/or prevention of disorders associated with loss of muscle mass and/or strength, in the field of compositions for disorders, capable of solving problems such as limited use of essential amino acid concentrations, reduced digestibility, etc.

Pending Publication Date: 2020-06-05
FRIESLANDCAMPINA NEDERLAND BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0011] However, the inventors have observed that the protein-dense low-viscosity composition according to EP2249666 has the disadvantage that it forms protein coagulums at gastric pH and thus exhibits reduced digestibility
Therefore, their use for increasing the concentration of essential amino acids in the blood (eg in the treatment and / or prevention of conditions associated with loss of muscle mass and / or strength) is limited

Method used

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  • Protein-dense nutritional compositions for use in treating and/or preventing condition linked to loss of muscle mass and/or strength
  • Protein-dense nutritional compositions for use in treating and/or preventing condition linked to loss of muscle mass and/or strength
  • Protein-dense nutritional compositions for use in treating and/or preventing condition linked to loss of muscle mass and/or strength

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Embodiment Construction

[0023] As used in this specification and claims, the verb "to comprise" and its conjugations are used in its non-limiting sense to mean that the item following the word is included, but does not exclude what is not specifically mentioned. and items.

[0024] In addition, reference to an element by the indefinite article "a" or "an" does not preclude the presence of more than one of an element, unless the context clearly requires the presence of an and only A / an element. Thus, the indefinite article "a" ("a" or "an") generally means "at least one".

[0025] The term "about" is used herein to indicate that certain deviations from the quoted value are permissible. The magnitude of this deviation depends inter alia on the precision of the method for determining the quoted value and is generally within ±10%, more particularly within ±5% of the quoted value.

[0026] The term "nutritional composition" as used herein refers to a nutritional composition comprising one or more of pr...

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Abstract

The invention relates to the field of protein-dense liquid nutritional compositions for use in the treatment and / or prevention of a condition linked to loss of muscle mass and / or strength. Provided isa heat-treated liquid high-protein composition comprising at least 10 g of protein per 100 ml of the composition, wherein at least 40 wt.% of the protein is micellar casein and at least 10 wt.% of the protein is hydrolysed whey protein having a degree of hydrolysation of at least 5%, and the weight ratio of micellar casein to hydrolysed whey protein is in the range of 40:60 to 90:10, for use in any one or more of the following of a) preventing or reducing coagulation in the upper gastro-intestinal tract; b) increasing the rate of gastric emptying; c) enhancing protein digestion; d) increasingthe blood serum concentration of free essential amino acids, preferably leucine, in the subject.

Description

technical field [0001] The present invention relates to the field of protein-dense liquid nutritional compositions. The present invention relates in particular to compositions for the treatment and / or prevention of conditions associated with loss of muscle mass and / or strength, in particular conditions involving malnutrition and loss of muscle mass. Background technique [0002] Loss of muscle mass and muscle strength greatly reduces mobility and quality of life in older adults and patients as they lose the ability to perform daily activities. Additionally, muscle loss impairs recovery, leading to more complications, infections, longer hospital stays and even death. Decreased reserve capacity (leading to increased risk of disability and other adverse health outcomes) was defined as frailty. When muscle mass, strength, and physical function fall below critical clinical levels, it is termed sarcopenia. This loss of muscle mass and strength can be gradual due to aging and / or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A23L2/66A23J3/10A23J3/34A23L33/00A23L33/18A23L33/19A61K38/17A61P21/06
CPCA23L2/66A23J3/10A23J3/343A61K38/018A61K38/1709A23L33/40A23L33/18A23L33/19A61P21/06A23V2002/00A23V2250/54246A23V2200/316A23L29/035A23L33/30A23L33/15A23L33/29A23J3/14
Inventor P·E·A·史莫德斯R·A·甘泽夫勒G·维兰M·H·肖马克
Owner FRIESLANDCAMPINA NEDERLAND BV
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