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An ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion

A technology of temperature change and ultrasonic system, applied in the direction of physical/chemical change thermometers, thermometers, thermometers using electric/magnetic elements that are directly sensitive to heat, etc., can solve unfavorable large-scale deployment, small evaluation errors, and complex solutions and other issues, to achieve the effect of easy large-scale deployment, small evaluation error, and strong readability

Active Publication Date: 2020-12-29
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] Aiming at the complex schemes in the prior art, high cost, and large errors, which are not conducive to large-scale deployment, the present invention provides an ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion, which can realize low-cost, The effect is easy to deploy on a large scale, and the evaluation error is small, and the readability is strong

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  • An ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion
  • An ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion
  • An ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion

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Embodiment 1

[0050]The present invention constructs a nonlinear model of the ultrasonic temperature evaluation algorithm based on the nonlinearity of the thermal expansion effect of biological tissues and the nonlinearity of the sound velocity change, uses the original echo signal of B-ultrasound, and combines the noise reduction technology of the physiological gating algorithm with high precision Measure temperature changes; and provide visual results. First, construct the corresponding detection system, such asfigure 1 As shown, heating probes 5 and 6 connected to heating devices 4 and 7 are used to heat the biological tissue 3, the imaging probe 2 of the ultrasonic diagnostic apparatus 1 is used for the biological tissue 3 to perform a B-scan, the heating devices 4, 7 and the ultrasonic diagnostic apparatus 1 Control by the control system 8, the control system 8 is controlled in a wireless or wired manner, and the control system 8 can be a computer or a control platform. The above system is u...

Embodiment approach

[0072]The specific implementation is as follows, taking focused ultrasound heating as an example, the method steps are as follows:

[0073](1) Use the imaging probe 2 of the ultrasonic diagnostic apparatus 1 to perform B-scan imaging on the biological tissue 3, and continuously output unprocessed original RF signals in chronological order. A heating probe or a focusing probe is used to locally heat the biological tissue corresponding to the central area of ​​the image; the heating equipment 4 and the ultrasonic diagnostic apparatus 1 are all controlled by the computer 8 and collect data. In this step, when the biological tissue is locally heated, eitherfigure 1 In the heating probe, you can also use an ultrasonic focusing probe.

[0074](2) Before focusing probe treatment, use an ultrasound diagnostic apparatus to collect signals of at least 2 cycles of physiological movement.

[0075](3) Select a frame of echo signal at the initial time of heating as the reference frame, and calculate the c...

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Abstract

The invention discloses an ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion, which belongs to the field of ultrasonic detection, and aims at the problem that the temperature rise of the target area cannot be effectively monitored in the current methods of treating diseases based on heating tissues in the body , established a method for evaluating the temperature change of biological tissue by using the original echo signal of B-ultrasound. This method uses focused ultrasound, radio frequency, microwave and other methods to locally heat biological tissues, uses B-mode ultrasound to image the target area and collects its original echo signals, and uses a dynamic frame selection algorithm to select target frame pairs based on B-mode ultrasound time-series images. Live noise is suppressed, and the time-delay image is calculated when the ultrasound passes through the tissue; then the temperature change image is obtained according to the nonlinear model of thermal expansion and sound velocity; this method has an error of no more than 3°C within a temperature rise of 30°C, which will promote The application of B-ultrasound temperature rise monitoring technology in hyperthermia can significantly improve the safety and effectiveness of hyperthermia.

Description

Technical field[0001]The present invention relates to the field of ultrasonic testing, and more specifically, to an ultrasonic method and system for evaluating temperature changes based on nonlinear thermal expansion.Background technique[0002]In the clinical treatment of tumors, hyperthermia has attracted widespread attention and is regarded as a minimally invasive or non-invasive surgical method of great significance. During the treatment process, excessive temperature may cause damage to the surrounding normal cells and cause serious side effects. If the temperature does not meet the clinical requirements, it may significantly reduce the efficacy and even cause treatment failure. Considering the safety and effectiveness of hyperthermia, it is necessary to monitor the temperature change process of biological tissues during treatment.[0003]Compared with other temperature imaging methods, due to its advantages of no ionizing radiation, flexibility, easy operation, low cost, portabili...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01K11/22G01K7/02G06K9/32G06K9/40
CPCG01K11/22G01K7/02G06V10/30G06V10/25
Inventor 郭霞生范鹏飞章东屠娟
Owner NANJING UNIV
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