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Paclitaxel medicine bag, and preparation method and application thereof

A technology of paclitaxel and drug packs, which is applied in the field of paclitaxel drug packs and its preparation, can solve the problems of inconvenient carrying and low utilization rate of active ingredients, etc., achieve breast and ovarian cancer prevention and treatment, inhibit the formation of cancer cells, and be suitable for The effect of mass production

Pending Publication Date: 2020-06-19
田大伟 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the utilization rate of active ingredients in the yew is low for this type of health care equipment, and it is also inconvenient to carry

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0046] The method for preparing the paclitaxel drug pack provided by the present invention includes the following steps:

[0047] a) The cleaned branches, leaves, stems, barks and roots are superfinely pulverized, and then dried until the moisture content is less than 3%;

[0048] b) The dried yew obtained in step a) is subjected to supercritical extraction to obtain an extract with paclitaxel purity greater than 99.5%;

[0049] c). Put the extract obtained in step b) into a prefabricated medicine bag with a radiation energy sheet on the outside, and seal it to obtain the paclitaxel medicine bag.

[0050] In some preferred embodiments of the present invention, in step a), before the ultrafine pulverization, it further includes: washing at least one of the branches, leaves, stems, barks, and roots of the fresh yew.

[0051] In some preferred embodiments of the present invention, in step c), the extract obtained in step b) and the pulverized Chinese medicinal materials are packed into a p...

Embodiment 1

[0055] The paclitaxel drug pack provided by the present invention is prepared by the following method:

[0056] a) The cleaned branches, leaves, stems, barks and roots are superfinely pulverized, and then dried until the moisture content is less than 3%;

[0057] b) The dried yew obtained in step a) is subjected to supercritical extraction, and the extract is spray-dried to obtain an extract with a purity of paclitaxel greater than 99.5%;

[0058] c). Put the extract obtained in step b) into a prefabricated drug bag of 5×6 cm nano silver fiber fabric with 3 radiation energy sheets on the outside, and seal it to obtain the paclitaxel drug package.

[0059] The paclitaxel drug pack includes 6g paclitaxel.

Embodiment 2

[0061] The paclitaxel drug pack provided by the present invention is prepared by the following method:

[0062] a) The cleaned branches, leaves, stems, barks and roots are superfinely pulverized, and then dried until the moisture content is less than 3%;

[0063] b) The dried yew obtained in step a) is subjected to supercritical extraction, and the extract is spray-dried to obtain an extract with a purity of paclitaxel greater than 99.5%;

[0064] c). Put the extract obtained in step b) into a prefabricated 5×5cm nanometer aluminum foil drug bag with 3 radiation energy sheets on the outside, and seal it to obtain the paclitaxel drug bag .

[0065] The paclitaxel drug pack includes 7g paclitaxel.

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Abstract

The invention provides a paclitaxel medicine bag, and a preparation method and an application thereof. The paclitaxel medicine bag comprises a medicine bag body and paclitaxel wrapped in the medicinebag body, wherein a radiation energy piece is arranged at one side of the exterior of the medicine bag body; and 0.3-0.52-3 kg of the paclitaxel is contained in each square meter of the medicine bag body in terms of the area of the medicine bag body. The paclitaxel medicine bag provided by the invention has the following advantages: the paclitaxel is stimulated through energy rays emitted by the paclitaxel medicine bag, so generation of cancer cells is restrained; meanwhile, heat generated by the energy rays and the human body temperature penetrates through a cloth to enter cells in the humanbody, so the treatment effect can be achieved when diseases exist, and the prevention effect can be achieved when the diseases do not exist. The paclitaxel medicine bag is placed in female underclothes, and the surface of the paclitaxel medicine bag without the radiation energy piece faces the human body, so the effects of preventing and treating breast cancer and ovarian cancer are achieved.

Description

Technical field [0001] The present invention relates to the technical field of medicine and health care, in particular to a paclitaxel drug pack and its preparation method and application. Background technique [0002] Taxus chinensis, also known as cypress, red bean tree, and yew, has a slightly sweet taste and flat sex. It can be used as medicine all over the body. It is distributed in the northern hemisphere. It is recognized as an endangered natural and rare cancer-fighting plant in the world. It is an ancient leftover from Quaternary glaciers Tree species have a history of 2.5 million years on earth. Due to the slow growth rate of yew under natural conditions and the poor regeneration ability, there has been no large-scale yew raw material forest base in the world for a long time. [0003] Taxus chinensis is rich in paclitaxel, protein, calcium, phosphorus, iron and other minerals and a variety of vitamins. It is a natural antioxidant and anti-aging plant. [0004] Paclitaxel ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K41/00A61K31/337A61K9/00A61P35/00
CPCA61K41/0038A61K31/337A61K9/009A61P35/00
Inventor 田大伟邱桂英黑田百香清水辉夫
Owner 田大伟
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