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A traditional Chinese medicine composition for dermatitis and preparation method thereof

A skin disease and composition technology, applied in the field of medicines for the treatment of skin diseases, can solve problems such as side effects that cannot be ignored, unstable curative effect, short action time, etc., and achieves inhibition of microvascular dilation, significant allergic itching and edema, inhibition of exudation and edema. The effect of subcutaneous inflammation and swelling

Active Publication Date: 2021-10-01
张琰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these therapeutic drugs and dosage forms can achieve a certain effect, the curative effect is unstable, the action time is short, drug resistance is easy to occur, and the disease recurs, and the side effects cannot be ignored.

Method used

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  • A traditional Chinese medicine composition for dermatitis and preparation method thereof
  • A traditional Chinese medicine composition for dermatitis and preparation method thereof
  • A traditional Chinese medicine composition for dermatitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A traditional Chinese medicine composition for dermatitis, made of the following raw materials in parts by weight: 18 parts of Cnidium Fructus, 9 parts of Notopterygium, 9 parts of Schizonepeta, 1 part of Borneolum, 18 parts of Sophora Sophorae, 27 parts of Comfrey, gallnut 6 parts, Kochia 9 parts, Sichuan pepper 9 parts.

[0044] Preparation method: take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extraction with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

Embodiment 2

[0046] A traditional Chinese medicine composition for dermatitis, made of the following raw materials in parts by weight: 10 parts of cnidium, 5 parts of notopterygium, 5 parts of Nepeta, 0.1 part of borneol, 5 parts of flavescens, 10 parts of comfrey, gallnut 5 parts, 5 parts Kochia, 5 parts Chuanjiao.

[0047] Preparation method: take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extraction with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

Embodiment 3

[0049] A traditional Chinese medicine composition for dermatitis, made of the following raw materials in parts by weight: 20 parts of Cnidium Fructus, 15 parts of Notopterygium, 15 parts of Schizonepeta, 3 parts of Borneolum, 20 parts of Sophora Sophora, 30 parts of Comfrey, gallnut 10 parts, 15 parts of Kochia scoparia, 15 parts of Chuanjiao.

[0050]Preparation method: take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extraction with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

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Abstract

The invention discloses a traditional Chinese medicine composition for dermatitis and a preparation method thereof, relates to the technical field of medicines for treating glucocorticoid-dependent eczema and dermatitis, and aims to solve the problem of unstable curative effect and duration of action of medicines in the prior art. Short, easy to produce drug resistance, easy to repeat the disease, and many technical problems, it is mainly aimed at the types of eczema and dermatitis that are easy to relapse after existing drug treatment, and hormone-dependent. The technical scheme of the present invention is as follows: it is made of the following raw materials in parts by weight: 1-35 parts of Cnidium Fructus Cnidii, 1-35 parts of Notopterygium, 1-35 parts of Schizonepeta, 0.1-10 parts of Borneolum, 1-35 parts of Sophora Sophorae, 1-35 parts of grass, 1-35 parts of Chinese gall, 1-35 parts of Kochia chinensis, 1-35 parts of Sichuan pepper.

Description

technical field [0001] The invention relates to the technical field of drugs for treating skin diseases, in particular to a traditional Chinese medicine composition for dermatitis and a preparation method thereof. Background technique [0002] Eczema is a skin inflammation caused by various factors such as the environment and the body itself. The disease can occur in any season and at any age. It is clinically manifested as polymorphic skin lesions. damp place. Skin pimple-like is the basic form of eczema, which is diverse in different patients. There are often local dark red macules, blisters, severe itching, easy to rupture when scratched, accompanied by exudation, and has been combined with chronic infection. Some patients have recurrent attacks. After long-term lesions, the skin is hypertrophic and rough, which not only affects the appearance, but also causes greater physical distress and psychological pressure for patients who have not been cured for a long time or has...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P17/00A61P17/04A61P37/08A61K31/045A61K35/64
CPCA61K31/045A61K35/64A61K36/185A61K36/234A61K36/237A61K36/30A61K36/489A61K36/538A61K36/758A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P17/00A61P17/04A61P37/08A61K2300/00
Inventor 张琰姜维石磊文一丁
Owner 张琰
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