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A kind of Chinese veterinary medicine Huangqi compound granules for promoting growth and enhancing immunity

A technology for enhancing immunity and astragalus, applied in the field of traditional Chinese veterinary medicine, can solve the problems of less research on the bioavailability of active ingredients of traditional Chinese medicine, less consideration of detoxification and efficiency enhancement, and less consideration of compatibility in the processing of traditional Chinese medicine, so as to enhance the ability of anti-oxidative stress , Improving the body's immunity and promoting the growth of animals

Active Publication Date: 2021-11-23
SHANXI UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the main problems in the research and development of traditional Chinese veterinary drugs are as follows: first, formulating prescriptions based on the theory of traditional Chinese medicine, with little consideration of the compatibility of traditional Chinese medicine; There are few new preparations, and there are few studies on the bioavailability of the active ingredients of traditional Chinese medicines; third, in the research and development of traditional Chinese veterinary medicines, there is little consideration for the reduction of toxicity and the enhancement of the processing of traditional Chinese medicines

Method used

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  • A kind of Chinese veterinary medicine Huangqi compound granules for promoting growth and enhancing immunity
  • A kind of Chinese veterinary medicine Huangqi compound granules for promoting growth and enhancing immunity
  • A kind of Chinese veterinary medicine Huangqi compound granules for promoting growth and enhancing immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 Safety Evaluation Acute Toxicity Test

[0042] Prescription: 3 parts of Radix Astragali, 3 parts of Imperata Rhizome, 1.5 parts of Raw Burnet, 1.5 parts of Rubia, 1.5 parts of Poria, 1 part of Radix Paeoniae Alba, 0.5 parts of Codonopsis, 1 part of fried Atractylodes macrocephala and 1 part of Licorice (recipe 3)

[0043] Preparation Process:

[0044] 1) Astragalus decoction pieces, using ethanol with a volume concentration of 70%, controlling the ratio of medicine to liquid to 1:5, cold soaking and extracting twice, each cold soaking for 36 hours, collecting the filtrate, and recovering the ethanol to obtain the Astragalus extract;

[0045] 2) Mix Radix Astragali with Rhizoma Imperatae, Radix Burnet, Rubia, Poria, Paeoniae Alba, Codonopsis, Stir-fried Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome and Radix Glycyrrhizae, extract with water (drug liquid ratio 1:5), temperature is 95...

Embodiment 2

[0054] Embodiment 2 quality standard research

[0055] Add sucrose and dextrin to the astragalus compound extract prepared in recipe 3 at a mass ratio of 1:1:0.8 to obtain astragalus compound granules;

[0056] The relevant experiments were carried out with the obtained Astragalus compound granules.

[0057] Reagents: standard glucose (National Institute for Food and Drug Control, batch number: 110833-201205), standard astragaloside (National Institute for Food and Drug Control, batch number: 110813-201206), ethanol (analytical grade, Tianjin Damao Chemical Co., Ltd. Reagent Factory), phenol, concentrated sulfuric acid (analytical grade, Hubei Xinrunde Chemical Co., Ltd.), vanillin (analytical grade, Tianjin Fuchen Chemical Reagent Factory).

[0058] Instruments: Pharmacopoeia sieve, desiccator, flat weighing bottle, TU-1810 UV-Vis spectrophotometer (Beijing General Instrument Co., Ltd.), AX124ZH 1 / 10,000 analytical balance (Ohaus Instruments Co., Ltd.), EX125ZH analysis Bal...

Embodiment 3

[0065] The influence of embodiment 3 on broiler growth

[0066] Example 3 uses Huangqi compound granules obtained from recipe 3 to carry out related experiments.

[0067] 100 healthy 1-day-old Ross 308 broilers were selected, mixed male and female, and after adaptive feeding for 7 days, they were randomly divided into 4 treatments according to the principle of no difference in repeated body weight, with 5 replicates in each group and 5 birds in each replicate. Experimental animals Broiler chickens were raised in three-layer cages and kept warm by infrared lamps. Each group was kept in isolation and had free access to food and water. On the 20th day, they were vaccinated with the new branch double-linked multivalent vaccine. From the first day to the 21st day of the test, chicken pellets (Wenshui Daxiang Poultry Industry Xiangfeng Feed Co., Ltd., trade name: chicken pellets) were used. From 22 to 42 days of the test, the control group was fed with meat-in-meat chicken compound...

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Abstract

The invention provides a traditional Chinese veterinary drug Huangqi compound granule for promoting growth and enhancing immunity and a preparation method thereof. Made from the following raw materials in parts by mass: 3 parts of Astragalus membranaceus, 1 to 3 parts of Rhizoma Imperatae, 0.5 to 2 parts of Burnet, 0.5 to 2 parts of Rubia, 1.5 to 2 parts of Poria cocos, 1 to 2 parts of Radix Paeoniae Alba, 0.5 to 2 parts of Codonopsis pilosula 1.5 parts, 1-2 parts of fried Atractylodes macrocephala and 1-2 parts of licorice. The research of the present invention shows that astragalus root and codonopsis pilosula are used as monarch drugs to prepare animal feed additives, which can promote animal growth and improve immunity. The invention provides a traditional Chinese veterinary medicine astragalus compound granule with stable action, safety, convenience and low price, which can promote growth and improve immunity, and create more economic and social values.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to Chinese veterinary medicine Astragalus compound granules for promoting growth and enhancing immunity and a preparation method thereof. Background technique [0002] Chinese veterinary medicine is a kind of traditional Chinese medicine. The functions of Chinese veterinary medicine are mainly reflected in the antibacterial effect, the effect of promoting animal growth and the effect of deworming. [0003] In the livestock and poultry industry, the main function of antibiotics is to promote growth. Improper use and abuse of antibiotics in livestock and poultry production pollute the environment and threaten human and animal health. The basic consensus on replacing antibiotics is that one is to replace antibiotics with acidifiers; the other is to use high-concentration metal ions instead of antibiotics to inhibit pathogenic microorganisms, such as zin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/16A61P3/00A61P37/04A61P39/00
CPCA61K9/1652A61K36/076A61K36/284A61K36/344A61K36/481A61K36/484A61K36/65A61K36/71A61K36/739A61K36/74A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P3/00A61P37/04A61P39/00A61K2300/00
Inventor 王颖莉贾颖王佳敏杨大伟
Owner SHANXI UNIV OF CHINESE MEDICINE
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