156results about How to "The effect is safe and reliable" patented technology

The invention relates to a new method for promoting the fruit coloring, private for fruit coloring. Spraying 10-40mg/l cytisoside containing 0.1% broad adhesive on the fruit surface, and one time is ok before the fruit matures, or immersing the fruit with 10-40mg/l cytisoside containing 0.1% broad adhesive for 3-5 s after harvesting the fruit, drying in the dark and keep for 12 h, then exposing the fruit to the artificial light source or sunlight for 3-5 days for coloring. The method can be used for coloring fruit such as apple, pear, peach, plum, apricot, grape and strawberry which cultivated with bag covered or without bag covered. The method is simple, high effective, fast and safe, improves the fruit coloring degree and apparent quality.

Provided is a coupling fracturing method for a hard coal bed roof. A drilling machine is utilized for drilling fracturing drill holes inside the hard roof till the design position, specifically, each static fracturing guide drill hole is formed between every two pulse hydraulic fracture drill holes so as to form a fracturing system; the fracture drill holes are connected to a pulse water injection pump through an isometric flow distributor with adjustable frequency, and the static fracturing drill holes are filled with static crushing agent slurry; under the action of expansion force of the static crushing agent slurry, initial cracks formed around the drill holes are monitored, released heat irradiates continuously towards the portions around the drill holes, a similarly elliptical temperature field is generated, and the elasticity modulus of a rock stratum is reduced; and under the action of hydraulic pressures of different frequencies, a fracture zone, a fatigue zone and an original stress zone are formed in the positions, around the fracture drill holes, of the rock stratum, when pressure water flows to the rock stratum bearing heat conduction along the cracks, the water and heat effect weakens the strength of the rock stratum, and the through time for crack zones among the drill holes is shortened. The method can sufficiently improve the utilization rate of the drill holes, operation is easy, and construction is safe and reliable.

The invention discloses a composition with moisturizing, soothing and repairing effects. The composition is prepared from the following components: Tujue rose flower extract, betaine, radix cynanchi atrati extract, bio-sugar gum-1, silane triol, hyaluronic acid, mother Chrysanthemum flower extract, European mallow flower extract, peony root extract, honeysuckle flower extract, European dandelion herb extract, herba violae extract, Aloe vera leaf juice, hydrolyzed silk, palmitoyl tetrapeptide-7, acetyl hexapeptide-8, hydrolyzed vegetable protein, cactus pear fruit extract, oat beta-glucan, allantoin, and hydrolyzed collagen; the composition has moisturizing, soothing and repairing effects; and can be added to cosmetics in different dosage forms. The invention also discloses a mask containing the composition, the mask has the functions of moisturizing, soothing and repairing. The invention also discloses a preparation method of the mask, the method has the advantages of simple process, easy control and high production efficiency.

The invention relates to an immunocompetent cells modified by dual chimeric antigen receptor genes based on CD19 and CD70 and an application thereof. The dual chimeric antigen receptors include the chimeric antigen receptor CD19 and the chimeric antigen receptor CD70. The chimeric antigen receptor comprises an antigen binding domain, a transmembrane domain, a costimulatory signal conducting regionand a CD3 zeta signal conduct domain, and an inducible suicide fusion domain connected in series. The chimeric antigen receptor of the present invention specifically recognizes tumor surface antigensCD19 and CD70, compared to the use of other single chimeric antigen receptor T cell, the combination of two antigens is used to target CAR-T cells so that the treatment effect is better, CD19 escapeis differently generated, and the disease is easily relieved.

A series of bone-setting medicines includes the exterior-applied ointment prepared from 6 Chinese-medicinal materials including pyrite, acanthopanax bark, ground beetles, etc, the interior-applied capsule prepared from 6 Chinese-medicinal materials including ground beetles, pyrite, Dragon's blood, sufflower, etc. and the medicinal wine prepared from epimedium, coix seed, achyranthes root and Chinese englica root. Its advantages include high curative effect and cure rate, quickly taking its effect and short course of treatment.

The invention relates to a pilot milling tool for repairing a casing by utilizing a pilot milling cone made of high-strength cemented alloy milling materials and a method thereof. The structure of thepilot milling cone comprises a connector, a body, milling materials on the body, a circulating water channel, a circulating water hole, a pilot hole and a central hole. The casing repairing method proposes the casing repairing method for using serialized pilot milling cone to mill and get through the channel by the guiding function of a cone pilot part at the front end and the correcting functionof a cylinder part at the back end and can effectively prevent damage to the casing or ejection of the milling cones from the casing during the milling construction. The casing repairing method and the tool thereof are applicable to casing-damaged wells which are severely bended and dislocated.

The invention relates to a folding discharging rubber belt conveyor, which comprises a front frame connected with the whole conveyor in a rotating manner, a rear frame connected with the front frame in a rotating manner, and a locking part and is characterized in that: the locking part consists of a hydraulic cylinder hinged to the whole conveyor, a steel wire rope I of which one end is fixedly connected with the hydraulic cylinder and the other end is fixedly connected with the front frame, pin holes and fixed pin shafts which are correspondingly formed in and arranged on the front frame and the rear frame, and locking pins for fastening the front frame and the rear frame after the front frame and the rear frame are folded; and the shapes, the sizes and the locking positions of the locking pins are matched with the structures of the folded front frame and the folded rear frame. The folding discharging rubber belt conveyor has the characteristics of convenience for operation, simple and compact structure, safe, stable and reliable effect and low cost.

The invention relates to a double chimeric antigen receptor gene-modified immune cell based on CD19 and BCMA and application thereof. A double chimeric antigen receptor comprises a chimeric antigen receptor CD19 and a chimeric antigen receptor BCMA. The chimeric antigen receptor is formed by connecting an antigen binding domain, a trans-membrane domain, a co-stimulatory signal conduction region, aCD3 zeta signal conduction domain and an inducible suicide fusion domain in series. The chimeric antigen receptor can specifically recognize tumor surface antigens CD19 and BCMA; and compared with the use of other mono-chimeric antigen receptor T cells, the combined use of two antigen-targeted CAR-T cells ensures that the treatment effect is better, the CD19 escape is hard to occur, and diseasesare more easily alleviated.

The invention discloses a pleurotus eryngii sterilization device, which comprises a steam sterilization tank, a high-temperature steam generator and a motor. The end is connected with a rotating shaft, the rotating shaft is vertically set, and the rotating shaft extends into the steam sterilization tank, and a plurality of grid plates are fixed on the rotating shaft. Bacteria bag, the present invention has simple and reasonable structure, convenient use and operation, high overall sterilization efficiency and good effect, so that each leaf can be fully sterilized, so the overall production efficiency is improved, and the overall operation of the equipment is stable and safe to use.

The invention relates to a double chimeric antigen receptor gene-modified immune cell based on CD19 and PSMA, and application thereof. A double chimeric antigen receptor comprises a chimeric antigen receptor CD19 and a chimeric antigen receptor PSMA. The chimeric antigen receptor is formed by connecting an antigen binding domain, a trans-membrane domain, a co-stimulatory signal conduction region,a CD3 zeta signal conduction domain and an inducible suicide fusion domain in series. The chimeric antigen receptor can specifically recognize tumor surface antigens CD19 and BCMA; and compared with the use of other mono-chimeric antigen receptor T cells, the combined use of two antigen-targeted CAR-T cells ensures that the treatment effect is better, the CD19 escape is hard to occur, and diseasesare more easily alleviated.

A lawn mower lifting machine includes a frame, a power device, a lifting device, a limit device and a support device. The frame includes a bottom frame and a jack installing board frame. The power device includes a jack with the top coupled to the lifting device and the bottom coupled to the frame. The lifting device includes a lift arm coupled between the frame and the power device. The limit device includes a brake block, a limit rack and a retractor coupled to the lifting device. The retractor can be turned to hook the brake block. The support device includes a lift beam, a lift frame coupled to both sides of the lift beam.

The invention discloses an additive for improving piglet immunity as well as a preparation method and application of the additive. The additive comprises 8-15 g of radix astragali preparata, 3-5 g of radix angelicae sinensis, 3-5 g of rhizoma polygonati, 3-5 g of radix codonopsitis, 5-10 g of prepared ovate atractylodes, 3-5 g of radix polygoni multiflori praeparata, 3-5 g of poria cocos, 2-3 g of pericarpium citri reticulatae, 10-20 g of rhizoma discoreae, 8-15 g of medicated leaven and 5-10 g of fructus ligustri lucidi. The invention further discloses the application of the additive for improving piglet immunity in adjustment of humoral immunity level of piglets and enhancement of specific immune function of body to improve disease resistance. Results show that the disease resistance of the piglets can be improved by adding immunity enhancing powder to weaned piglet feed to adjust the specific immunity of the piglets.

The invention relates to a fludarabine phosphate freeze-dried powder injection, wherein fludarabine phosphate is the only ingredient of the fludarabine phosphate freeze-dried powder injection. According to a preparation method, finished products are preferably prepared by mixing 75 to 100<mu>m of fludarabine phosphate powder with injection water, and an obtained solution with a fludarabine phosphate concentration ranging from 5 to 20% is subjected to freeze drying. The preparation method is simple; operation is convenient; and the preparation method is suitable for industrialized production.

The invention discloses a precise control device for rolling pressure of a lower fillet of a high-strength bolt head. The device comprises an elastic compensation system (6), a force sensor (5), a bolt rolling device (4), a main shaft system (2) and a control system (3), wherein the main shaft system (2) is fixed on the upper part of a rack (1) through a bearing. The device is characterized in that: the elastic compensation system (6) is fixed above a servo driving device (7); the bolt rolling device (4) is arranged above the elastic compensation system (6); and the control system (3) is connected with the main shaft system (2), the servo driving device (7) and the force sensor (5). The shell of the servo driving device (7) is fixed on the lower part of the rack (1). The device can precisely control the rolling force value, improve the production efficiency and ensure the product quality.

The invention relates to a metal ion-enhanced antibacterial polymer and a preparation method thereof. The metal ion-enhanced antibacterial polymer is mainly prepared from, by weight, 0.1-28 parts of ametal ion-enhanced antibacterial composition, 0-30 parts of a functional assistant, 0-5 parts of a dispersant and 100 parts of a polymer material; and the metal ion-enhanced antibacterial compositionis composed of 100 parts of at least one metal inorganic compound, 0.1-50000 parts of an antibacterial and mildew-proof agent and 0-4000 parts of a carrier. The metal ion-enhanced antibacterial composition is introduced into the antibacterial polymer of metal ion-enhanced antibacterial polymer, and metal ions are combined with an antibacterial and mildew-proof agent, so the amount of the antibacterial agent added to the polymer is reduced, the antibacterial polymer has a broad antibacterial effect, is safe, and achieves good balance between fast sterilization and long-lasting slow release, and the raw material cost of the antibacterial polymer is reduced.