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A skin barrier repair compound, face cream and preparation method thereof

A skin barrier and compound technology, applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc., can solve problems such as skin barrier damage, maintain homeostasis and basic health, resist external pressure, and relieve sensitivity problem effect

Active Publication Date: 2021-04-02
广州一一生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The composition prepared by the present invention can be used to promote the repair of skin barrier damage, especially for promoting the repair of skin barrier damage after laser cosmetic treatment, but the composition can only play the role of moisturizing, soothing and anti-inflammation, and has no Fundamentally solve the problem of damaged skin barrier

Method used

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  • A skin barrier repair compound, face cream and preparation method thereof
  • A skin barrier repair compound, face cream and preparation method thereof
  • A skin barrier repair compound, face cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0072] This preparation example prepares a sea fennel callus culture filtrate, and the preparation method of the sea fennel callus culture filtrate comprises the following steps:

[0073] (1) Callus induction culture: sea fennel explants were inoculated into agar medium for callus induction culture, the temperature of the induction culture was 20°C, and the time of the induction culture was 14 days, and the callus was obtained. injured tissue;

[0074] (2) Callus particle suspension culture: inoculate the callus obtained in step (1) into MS medium, and carry out shaking culture in a shaking incubator at a speed of 100 r / min, and the temperature of the shaking culture is 20°C , the time of the shaking culture is 14 days to obtain the proliferation callus;

[0075] (3) Expanded culture of callus: inoculate the proliferated callus obtained in step (2) into a sterile cell bag for expanded culture, the temperature of the expanded culture is 25°C, and the time of the expanded cultu...

preparation example 2

[0078] This preparation example prepares tetrahydromethylpyrimidine carboxylic acid, and the preparation method of described tetrahydromethylpyrimidine carboxylic acid comprises the following steps:

[0079] (A) Cultivation of desert halophilic bacteria: the desert halophilic bacteria were inoculated in SCDLP liquid medium, and cultivated with a rotating speed of 1000r / min in a shaking incubator, and the temperature of the cultivation was 20°C. The time is 48h, and the desert halophilic bacteria cell is obtained;

[0080] (B) Osmotic pressure shock: the desert halophilic bacteria bacterium that step (A) obtains is resuspended in hyperosmotic pressure solution (the hyperosmotic pressure solution comprises: 18% sucrose, 0.1% EDTA, remaining Soak in water) for 1 hour, filter to obtain the precipitated desert halophilic bacterial cell;

[0081](C) Electrodialysis: the desert halophilic bacterial cells obtained in step (B) are treated by electrodialysis to obtain tetrahydromethyl ...

preparation example 3

[0083] This preparation example prepares a kind of hydrolyzed red algae extract, the preparation method of described hydrolyzed red algae extract comprises the following steps:

[0084] (a) Extraction: wash, crush and pass through a 100-200 mesh sieve to obtain the red algae powder; add water to the red algae powder and perform an extraction at 70°C, and the time for the first extraction is 10 hours , the mass ratio of the water and the red algae powder is 20:1, the primary extract is obtained, the primary extract is filtered and then concentrated, then the volume ratio concentration is added to an aqueous ethanol solution of 80% for secondary extraction, and the precipitate is left to stand, Obtain red algae polysaccharide crude material;

[0085] (b) Hydrolysis: after dissolving the crude red algae polysaccharide obtained in step (a) with water, add 30wt% hydrogen peroxide aqueous solution, and mix and stir at 50°C for 1 hour to obtain a hydrolyzed red algae extract;

[008...

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Abstract

The invention provides a skin barrier repairing complex, facial cream and a preparation method therefor. The skin barrier repairing complex comprises a composition for repairing skin barrier, hydroxylasiaticoside, deacidified carnosine, a glycyrrhiza inflata root extract, a radix scutellariae extract and a hamamelis extract, wherein the composition for repairing skin barrier comprises sea fennelcallus culture filtrate, Ectoin and a hydrolyzed red alga extract. The skin barrier repairing complex can achieve triple effects of simultaneously repairing cutin barrier, repairing immunologic barrier and strengthening microbiologic barrier; and the facial cream prepared from the skin barrier repairing complex is obvious in repairing effect and can be used for effectively improving hydrature of skin, increasing the content of hyaluronic acid in the skin, improving photoaging, helping cell saccharification reversing and reducing fine grain area.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a skin barrier repair compound, face cream and a preparation method thereof. Background technique [0002] The outermost layer of the skin, called the stratum corneum, is made up of 20 layers of flat, interwoven horny cells. Keratinocytes are as tough as "bricks", and there are "mortar" lipids that tightly connect the keratinocytes to each other to form a "brick wall structure". Forms the skin barrier. The skin barrier can lock skin moisture and oil, and resist the invasion of various skin surface bacteria, which plays a very important role in protecting human health. [0003] Excessive exfoliation, UV sunburn, sensitive inflammatory damage, excessive cleaning, improper use of skin care products (such as excessive pursuit of strong efficacy products, high vitamin A concentration, use of unscrupulous masks) and other reasons caused by the use of exfoliating product...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/49A61K8/9717A61K8/9789A61K8/64A61K8/60A61K8/73A61K8/58A61Q19/00A61Q19/08A61Q17/04A61Q17/00
CPCA61K8/4953A61K8/585A61K8/602A61K8/64A61K8/735A61K8/99A61K2800/592A61K2800/5922A61K2800/782A61Q17/005A61Q17/04A61Q19/00A61Q19/005A61Q19/007A61Q19/08A61K8/9717A61K8/9789
Inventor 范玉菡温伟红陈奋佳刘金玉
Owner 广州一一生物技术有限公司
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