A multi-harness selection method with optimal biological effects
A biological and effect technology, applied in the field of radiophysics, can solve the problems of omission, damage, inability to guarantee the distribution of high-dose areas of tumors, etc., to achieve the effect of improving the success rate
Active Publication Date: 2021-10-19
SHANDONG RES INST OF TUMOUR PREVENTION TREATMENT +2
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Problems solved by technology
High-energy X-rays have unique physical characteristics. The maximum dose is at a certain depth under the skin. After the area is built up, the dose decays exponentially with the increase in tissue depth. The percentage depth dose varies with the radiation dose, irradiation field area, and source-skin distance Therefore, it is impossible to ensure that the entire tumor has a uniform distribution of high-dose areas in the three-dimensional direction
The shape of individual tumors will also change with the advancement of radiotherapy, and it is necessary to adjust the radiotherapy target area, revise the dose or irradiation mode in real time, because small morphological changes may move the high-dose area to the surrounding normal tissues that should not be irradiated. A precise hit can turn into a precise damage or miss
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[0022] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on The embodiments of the present invention and all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0023] see figure 1 , the present invention provides a technical solution: a multi-wire harness selection method with the best biological effect, specifically formulating the process:
[0024] (1) The CBCT machine is used for multi-angle scanning irradiation, and the algorithm based on wavelet transform is used to extract the characteristics of the tumor lesion area. The specific process is as follows:
[0025] use Represents the tumor image ...
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The invention discloses a multi-wire beam selection method with optimal biological effects. The present invention utilizes the different characteristics of multi-energy beams, monitors the changes of tumor position and shape in the radiotherapy process in real time, and finds out the best radiation and dose distribution mode with the best biological effect through statistical analysis, so as to ensure that the whole radiotherapy process always has The treatment state with the best biological effect can improve the tumor control rate.
Description
technical field [0001] The invention belongs to a radiotherapy multi-beam selection method with the best biological effect, and specifically relates to the field of radiation physics. Background technique [0002] Radiation therapy is one of the main local treatments for malignant tumors. About 70% of cancer patients need radiation therapy, and 40% of patients can be cured by radiation therapy. Radiation sources commonly used in radiotherapy include radiation produced by radioisotopes and high-energy x-rays, electron beams, proton beams, neutron beams and other particle beams produced by various accelerators. The commonly used irradiation methods of radiotherapy include two types of long-distance and brachytherapy. During teletherapy, the radiation must pass through normal tissues to reach the tumor tissue. Radiation rays of different energies are selected and multi-field irradiation techniques are used. [0003] Tumor growth has no fixed shape, and malignant tumors are ge...
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IPC IPC(8): A61N5/10
CPCA61N5/1031
Inventor 袁双虎李玮李莉韩毅刘宁马志祥袁朔吕慧颖于金明
Owner SHANDONG RES INST OF TUMOUR PREVENTION TREATMENT