Cardiac surgery autologous pericardium patch processor and rapid anti-calcification processing method

Abstract

The invention discloses a rapid anti-calcification processing method of a cardiac surgery autologous pericardium patch. The method comprises the following steps: (1) soaking the dirty layer of the autologous pericardium patch, which is taken down, by using a glutaraldehyde solution, and flattening by pressing; (2) soaking the pericardium patch in a first processing solution prepared from polyethylene glycol and a tris-hydrochloric acid buffer solution, and then rinsing with warm normal saline; (3) putting the pericardial patch into a second processing solution prepared from warm normal salineand a magnesium chloride solution, soaking and rinsing; and (4) trimming into a required shape to obtain the autologous pericardium patch for a heart defect repair operation. The method sequentially comprises the steps of flattening and shaping, polyethylene glycol tanning, magnesium ion impregnation and the like. All the steps are sequentially connected and cooperatively matched, so that the prepared autologous pericardium patch has a good anti-calcification effect, animal experiments and clinical application can effectively prevent the autologous pericardium patch from calcifying and losingpower after cardiac surgery, and the operation is simple and rapid.

Description

technical field [0001] The invention relates to an autologous pericardial patch processor in cardiac surgery, and a treatment method for preventing autologous pericardial calcification in combination with the use of the autologous pericardial patch processor. Background technique [0002] Patch materials are often used in heart repair in cardiac surgery, and autologous fresh pericardium slices are the most ideal material because they are cheap and easy to obtain. However, due to the softness of the fresh pericardium, it is difficult to clamp during surgical suturing, so it is often necessary to treat it with glutaraldehyde solution to make it shape so as to facilitate clamping and suturing. However, autologous pericardial slices treated with glutaraldehyde solution lose their activity, and are prone to secondary calcification and loss of function. At the same time, the commonly used glutaraldehyde solution to treat the pericardium is mostly soaked in a basin-shaped vessel, ...

AI Technical Summary

Problems solved by technology

However, autologous pericardial slices treated with glutaraldehyde solution lose their activity, and are prone to secondary calcification and loss of function

At the same time, the commonly used glutaraldehyde solution to treat pericardium is mostly soaked in a basin-shaped vessel, and the treated pericardium is often curled and uneven, which also causes certain difficulties for surgical suturing and pruning.

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