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System for assessing ovarian reserve function in subject

A technology for ovarian reserve and subjects, applied in medical data mining, surgery, catheterization, etc., can solve the problems of difficult, resource-consuming, and time-consuming AFC reliable assessment

Active Publication Date: 2020-08-11
GUANGZHOU KANGRUN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, obtaining good AFC results requires ultrasonography by skilled transvaginal sonography (TVS) specialists, which is time- and resource-intensive
Lack of standards in AFC measurement, AFC changes with menstrual cycle, contraceptive use, and TVS device sensitivity and resolution, all existing confounding factors can make reliable assessment of AFC more difficult

Method used

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  • System for assessing ovarian reserve function in subject
  • System for assessing ovarian reserve function in subject
  • System for assessing ovarian reserve function in subject

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Experimental program
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Embodiment

[0152] In the embodiment, the sample size is estimated first, the total sample size should be >553, and all couples are trying to conceive for at least 12 months.

[0153] According to the following inclusion and exclusion criteria, a total of 561 couples were enrolled in the three reproductive medicine centers for this study, that is, 561 couples who met the following inclusion and exclusion criteria were selected for subsequent research.

[0154] The inclusion criteria were: women aged 20-45 years, body mass index (BMI) ≤ 30, six consecutive menstrual cycles of 25-45 days, normal bilateral ovarian morphology assessed by transvaginal ultrasonography, previous IVF / ICSI- ET cycle number ≤ 2.

[0155] The exclusion criteria were: hydrosalpinx, unilateral ovary AFC>20, polycystic ovary syndrome, other untreated metabolic or endocrine diseases, previous surgery for the ovary or uterine cavity, intrauterine abnormalities, pregnancy within 3 months, Smoking, using oral contraceptiv...

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Abstract

The invention relates to a system for optimized assessment of an ovarian reserve function in a subject. The system comprises: a data acquisition module, which is used for acquiring data of the age, the anti-mullerian hormone (AMH) level, the follicle-stimulating hormone (FSH) level of the subject; and a module for calculating the ovarian reserve function, wherein the module is used for calculatinginformation acquired in the data acquisition module so as to calculate the probability (p) of the low ovarian response of the subject.

Description

technical field [0001] The present invention relates to an optimized system for evaluating the ovarian reserve function of a test subject, which can be used to assess the condition of the test subject's own ovarian reserve function, to assess its fertility potential, and to assess the test subject after undergoing Whether fertility potential improves after corresponding treatment. Background technique [0002] The number of primordial follicles contained in the ovarian cortex is called the ovarian reserve. It reflects the ability of the ovary to provide healthy eggs that can be fertilized successfully, and is the most important evaluation index of female ovarian function. Generally speaking, the greater the number of primordial follicles, the better the quality and the higher the chance of conception. [0003] Evaluation of ovarian reserve function can help women of childbearing age understand their fertility status so that they can reasonably arrange their own family plan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/70G16H50/30A61B8/12
CPCA61B8/12G16H50/30G16H50/70
Inventor 乔杰徐慧玉李蓉冯国双韩勇
Owner GUANGZHOU KANGRUN BIOTECHNOLOGY CO LTD
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