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A traditional Chinese medicine composition for treating skin rash caused by antineoplastic drugs

A technology of anti-tumor drugs and compositions, applied in the directions of anti-tumor drugs, drug combinations, drug delivery, etc., can solve the problems of neglect of patients' overall survival, lack of high-quality clinical research evidence support, and inaccurate clinical efficacy, etc. Safety, improvement of quality of life, positive effect of curative effect

Active Publication Date: 2021-07-16
浙江省中医院、浙江中医药大学附属第一医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] For skin rashes caused by anti-tumor drugs at home and abroad, the clinical efficacy is uncertain, lack of high-quality clinical research evidence support, some studies only stay in clinical experience and preventive drug research, lack of consideration of the intensity of anti-tumor treatment, and ignore the overall survival of patients

Method used

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  • A traditional Chinese medicine composition for treating skin rash caused by antineoplastic drugs
  • A traditional Chinese medicine composition for treating skin rash caused by antineoplastic drugs
  • A traditional Chinese medicine composition for treating skin rash caused by antineoplastic drugs

Examples

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Effect test

Embodiment 1

[0042] Prescription: 4G, glutinous rice, 20g, gold and silver, 20g, angelica 15g, 12g of mysterious 15g, white peony, licorice, 12g, licorice, 12g, and licorice, 12g, mysterious 15g, white peony

[0043] Preparation method: Take the raw material medicine, add 10 times quality water, fry twice, filtrate, concentrate, filter, and package it into a 100ml / bottle of packaging.

[0044] Usage: Apply directly to the rash part.

Embodiment 2

[0046] Prescription: 18 parts by weight of the southern red tap, 30 parts by weight of the glutinous rice, 30 parts by weight of the reed, 20 parts by weight of the angelica, 15 parts by weight of the square, 9 parts by weight of white peony, 15 parts by weight, licorice 15 weight Copy;

[0047] Preparation method: Take the raw material drug, 50% ethanol reflux, combined with extract, filter, recover ethanol, dissolve, concentrate under reduced pressure 1.10 (60 ° C), centrifuge at high speed, take the supernatant, join convention Accessories, external formulations are made.

[0048] Usage: Apply directly to the rash part.

Embodiment 3

[0050] Prescription: Nanguang 9g, coix seed 10g, honeysuckle 10g, reed 10g, angelica 10g, 5g of mysterious 9g, white peony 3g, licorice 5g;

[0051] Preparation method: The preparation method of Example 1.

[0052] Usage: Apply directly to the rash part.

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Abstract

The invention provides a traditional Chinese medicine composition for treating skin rash caused by antineoplastic drugs, which comprises the following components by weight: 9-18 parts by weight of Taxus chinensis, 10-30 parts by weight of coix seed, and 10-30 parts by weight of honeysuckle , 10-30 parts by weight of reed stem, 10-20 parts by weight of angelica, 9-15 parts by weight of trichosanthes, 9-20 parts by weight of Scrophulariaceae, 3-9 parts by weight of Angelica dahurica, and 5-15 parts by weight of licorice. The invention can significantly improve and cure skin rashes caused by antitumor drugs in a short period of time, is safe to use, has definite curative effect, and obviously improves the quality of life of patients without reducing the intensity of antitumor treatment.

Description

Technical field [0001] The present invention belongs to the technical field of Chinese medicine, and more particularly to a Chinese medicine composition for treating antitumor drugs. Background technique [0002] Today, the skin adverse reactions caused by anti-tumor drugs are not uncommon, among them, rash is a major problem that plagues the treatment decisions of clinicians. About 2 / 3 patients have rash, while 32% of patients are serious The rash had to reduce the drug dose or even stop the drug. Therefore, it not only affects the quality of life, but also, it has weakened the anti-tumor treatment strength, reducing efficacy until the patient's survival is shortened, and even because of severe infection directly threatens the patient's life. [0003] Anti-tumor drug relevance rash is a characteristic skin toxic reaction, more in drug treatment for 2-4 weeks, the rash type is diverse, mainly including acne-like male rash, spatum hemorrhage, seborriometry rash, dermatitis Sample ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P17/00A61P35/00
CPCA61K9/0014A61K36/13A61K36/232A61K36/355A61K36/428A61K36/484A61K36/808A61K36/899A61K36/8994A61P17/00A61P35/00A61K2300/00
Inventor 舒琦瑾陈舒怡寿柳梅陈赐慧
Owner 浙江省中医院、浙江中医药大学附属第一医院
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