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Traditional Chinese medicine composition for treating Parkinson disease and preparation method thereof

A technology for Parkinson's disease and a composition is applied in the field of traditional Chinese medicine compositions for treating Parkinson's disease and the field of preparation thereof, which can solve the problems of inability to delay the progression of the disease course, decline in drug efficacy, and no disease-modifying effect, and achieve good application prospects and suitable for use. For long-term use, the therapeutic effect is remarkable

Inactive Publication Date: 2020-10-16
高筱雅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the Western medicine treatment of PD mainly uses compound levodopa preparations, dopa receptor agonists, COMT enzyme inhibitors, MAOB inhibitors, amantadine, cholinergic inhibitors, etc. These drugs can only temporarily improve symptoms, but do not The disease-modifying effect cannot delay the progress of the disease, and with the progress of the disease, the efficacy of the drug decreases progressively, and the complications and side effects caused by the drug gradually appear

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A traditional Chinese medicine composition for treating Parkinson's disease, which is made of the following raw materials: 24g turtle shell (decocted first), 1g velvet antler (milled), 12g sea cucumber (milled), 30g chicken yellow (afterwards), wine Angelica 12g, Paeoniae Alba 15g, Cistanche 12g, American ginseng 12g (milling), Beiqi 15g, Atractylodes macrocephala 15g, Yunling 12g, Faxia 8g, bamboo leek 30g, Gastrodia elata 15g, Uncaria 10g (below), oyster 20g (decocted first), 4g Schisandra chinensis, 8g Shichangpu, Polygala 6g, scorpion 3g (milling), centipede 2g (head and feet removed, milling), earthworm 6g (milling), papaya 12g, kudzu root 20g and Achyranthes bidentata 10g.

Embodiment 2

[0027] A traditional Chinese medicine composition for treating Parkinson's disease, made of the following crude drugs: 28g turtle shell (decocted first), 2g velvet antler (milled), 12g sea cucumber (milled), 40g chicken yellow (afterwards), wine Angelica 18g, Paeoniae Alba 12g, Cistanche 13g, American ginseng 10g (milling), Beiqi 15g, Atractylodes macrocephala 15g, Yunling 12g, Faxia 8g, bamboo leek 30g, Gastrodia elata 15g, Uncaria 10g (below), oyster 25g (decocted first), 5g Schisandra chinensis, 10g Shichangpu, 8g polygala, 4g whole scorpion (milled), 3g centipede (removed head and feet, milled), 4g earthworm (milled), 15g papaya, 18g kudzu root and Achyranthes bidentata 15g.

Embodiment 3

[0029] A traditional Chinese medicine composition for treating Parkinson's disease, made of the following raw materials: 20g turtle shell (decocted first), 1g velvet antler (milled), 13g sea cucumber (milled), 50g chicken yellow (afterwards), wine 22g Angelica, 15g Paeoniae Alba, 12g Cistanche, 12g American Ginseng (milling), 20g Beiqi, 15g Atractylodes Rhizoma, 15g Yunling, 6g Faxia, 20g Bamboo Lek, 12g Gastrodia elata, 15g Uncaria (below), oyster 30g (fried first), Schisandra chinensis 6g, Shichangpu 8g, polygala 10g, scorpion 3g (milling), centipede 2g (head and feet removed, milling), earthworm 6g (milling), papaya 13g, kudzu root 24g and Achyranthes bidentata 12g.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating Parkinson disease and a preparation method thereof. The traditional Chinese medicine composition for treating the Parkinson disease is prepared from the following raw materials in parts by weight: 15-30 parts of tortoise plastron, 1-3 parts of pilose antler, 12-15 parts of sea cucumber, 20-50 parts of fresh egg yolk, 12-24 parts of Chinese angelica roots processed with liquor, 12-15 parts of white peony roots, 12-15 parts of herba cistanches, 10-12 parts of American Ginseng, 15-30 parts of Radix Astragali, 12-20 parts of white atractylodes rhizomes, 12-15 parts of poria cocos from Yunnan of China, 6-10 parts of processed pinellia tubers, 20-30 parts of bamboo sap, 12-15 parts of gastrodia, 10-15 parts of gambirplant nod, 15-30 parts of oyster, 4-6 parts of schizandra Chinensis baillon, 8-10 parts of grassleaf sweetflag rhizome, 6-10 parts of milkwort roots, 2-5 parts of whole scorpions, 1-3 parts of centipedes, 3-6 parts of earthworms, 12-15 parts of papaya, 15-24 parts of kudzuvine roots, and 10-15 parts of radix achyranthis bidentatae. The traditional Chinese medicine composition disclosed by the invention has the advantages of being capable of improving motor and non-motor symptoms of the Parkinson disease, free of obvious toxic and side effects and the like; and moreover, a brain-nourishing andwind-calming convulsion eliminating rule is adopted so as to be an adequate remedy for the disease, thereby achieving the curative effect of effectively treating the Parkinson disease. In addition, monarch-official-assistant-messenger medicines are used in compatibility so that the traditional Chinese medicine composition is capable of treating the Parkinson disease in a multi-target and multi-level way; and thus, the traditional Chinese medicine composition is significant in curative effects, suitable for long-term use, and good in application prospects.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine composition for treating Parkinson's disease and a preparation method thereof. Background technique [0002] Parkinson's Disease (PD) is the second largest degenerative disease of the nervous system, with an annual incidence of about 362 / 100,000. In 2005, the number of Parkinson's patients in my country reached 2 million [1], which has brought great benefits to the society. heavy medical burden. The typical pathological changes of Parkinson's disease are the formation of Lewy bodies in neurons and the progressive loss of dopaminergic neurons in the substantia nigra compacta of the midbrain. Therefore, it is important to protect dopaminergic neurons and reduce the apoptosis and loss of dopaminergic neurons The fundamental means to delay the progression of the disease. However, current clinical treatments for Parkinson's disease can only improve sym...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/16A61K35/32A61K35/57A61K35/586A61K35/616A61K35/618A61K35/62A61K35/646A61K35/648
CPCA61K35/32A61K35/57A61K35/586A61K35/616A61K35/618A61K35/62A61K35/646A61K35/648A61K36/076A61K36/21A61K36/232A61K36/258A61K36/284A61K36/481A61K36/488A61K36/57A61K36/64A61K36/65A61K36/69A61K36/71A61K36/732A61K36/74A61K36/888A61K36/8888A61K36/8988A61K36/899A61K2236/331A61K2236/55A61P25/16A61K2300/00
Inventor 高筱雅崔美琪梁晓媚
Owner 高筱雅
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