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Application of umbelliferone in preparation of medicine for treating vaginitis

A technology of umbelliferone and vaginitis, which is applied in the field of umbelliferone and can solve the problems of untreated vaginitis and the like

Inactive Publication Date: 2020-10-30
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report on the treatment of vaginitis

Method used

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  • Application of umbelliferone in preparation of medicine for treating vaginitis

Examples

Experimental program
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Effect test

Embodiment 1

[0013] Determination of antibacterial activity of umbelliferone against bacteria isolated from vagina in vitro by Oxford cup method

[0014] Staphylococcus aureus (genus name Staphylococcus species name aureus) ATCC 25923, purchased from Beijing Zhongke Quality Inspection Biotechnology Co., Ltd. in September 2018, product ID 119146, website: http: / / www.bzwzw.com / ;

[0015] Escherichia coli (genus name Escherichia species name coli) ATCC 25922, purchased from Beijing Zhongke Quality Inspection Biotechnology Co., Ltd. in September 2018, product ID 119128, website: http: / / www.bzwzw.com / ;

[0016] Pseudomonas aeruginosa (genus name Pseudomonas species name aeruginosa) ATCC 27853, purchased from Beijing Zhongke Quality Inspection Biotechnology Co., Ltd. in September 2018, product ID 125579, website: http: / / www.bzwzw.com / ;

[0017] Enterococcus faecalis (genus name Enterococcus species name faecalis) ATCC 29212, purchased from Beijing Zhongke Quality Inspection Biotechnology C...

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Abstract

The invention discloses application of umbelliferone in preparation of a medicine for treating vaginitis, and experiments prove that umbelliferone has an inhibition effect on fungi and bacteria causing vaginitis.

Description

technical field [0001] The present invention relates to a new application of umbelliferone. Background technique [0002] Vaginitis is a common gynecological disease that plagues many women, with a high incidence and complicated etiology. Most of the reasons why women suffer from vaginitis are that the vagina is affected by parasitic microorganisms, which leads to the disorder of the relationship between the mutual restriction and balance of the normal flora in the vagina, resulting in inflammation. Vaginitis is mainly manifested as burning sensation, genital itching, and increased leucorrhea. Common pathogenic bacteria that easily induce vaginitis include Candida, Enterobacter, and Staphylococcus. Most of the drugs currently used for the treatment of vaginitis are antibiotics, which are highly targeted, but have large toxic and side effects. Therefore, need a kind of pertinence badly, the medicine for the treatment of vaginitis that toxic side effect is little. [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/37A61P15/02A61P31/04A61P31/10
CPCA61K31/37A61P15/02A61P31/04A61P31/10
Inventor 何新
Owner GUANGDONG PHARMA UNIV
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