Unlock instant, AI-driven research and patent intelligence for your innovation.

Combined detection card for immunodetection and cell analysis and combined detection method

A technology of immune detection and detection card, applied in the field of biomedical detection, can solve the problems of high cost, low efficiency, and large demand for blood collection, and achieve the effect of taking into account precision and avoiding air bubbles

Pending Publication Date: 2020-11-10
苏州中科苏净生物技术有限公司
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, in clinical testing, immune testing and cell analysis (including cell counting and typing analysis) are generally carried out separately, and two different instruments are used for testing, which has low efficiency, high cost, and a large demand for blood collection, especially for emergency conditions. Testing efficiency and speed are critical to reducing patient waiting time and physician workload
[0009] At present, there is no combined detection instrument for POCT-level immunoassay and cell analysis. In view of the urgent need for combined detection equipment for POCT-level immunoassay and cell analysis, it is necessary to design and develop a test card for immunoassay and cell analysis to adapt to The demand for joint detection of immune and cell on-site

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Combined detection card for immunodetection and cell analysis and combined detection method
  • Combined detection card for immunodetection and cell analysis and combined detection method
  • Combined detection card for immunodetection and cell analysis and combined detection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Cell analysis module 400:

[0069] Figure 1A-Figure 1C It is an example of the structure of the cell analysis module of the present invention. Figure 1A-Figure 1C In the first embodiment of the cell analysis assembly shown, the cell analysis assembly 400 includes an assembly handle 1 and a test cavity 2 arranged on the assembly handle 1, wherein the tail end of the assembly handle 1 is a hand-held part, which is designed to be suitable for hand-held Shape, as in the first embodiment, the handle is rectangular, and the front end of the assembly handle 1 is extended with a test cavity 2 with arc-shaped edges; the test cavity 2 can be integrally formed with the assembly handle 1, or the test cavity 2 can be bonded to the front end. The test chamber 2 is a semi-open cavity formed by two parallel cavity side walls 3 with a certain gap, including the sample inlet 5, the sample injection gap 8, the test area 4 and the drainage connecting the sample inlet 5 and the test a...

Embodiment 2

[0094] Figure 2A-Figure 2C A second embodiment of a cell analysis assembly is shown. The structure of the second embodiment is a further improvement on the basis of the structure of the first embodiment, and its difference from the structure of the first embodiment is that:

[0095] In order to further avoid the generation of air bubbles, the test chamber 2 is provided with at least one exhaust hole 7, which is a through hole connecting the interior of the test chamber 2 with the outside atmosphere, and can be located on one side of the test area 4 or the drainage area 6 or Both sides can be symmetrical or asymmetrical through holes, that is, the exhaust hole 7 runs through one side wall of the test area 4 or the drainage area 6 or symmetrically runs through the two cavity side walls of the test area 4 or the drainage area 6 . Preferably, the exhaust hole 7 is a symmetrical inverted tapered through hole, that is, the small tapered end opens toward the inside of the drainage ...

Embodiment 3

[0102] Figure 3A-Figure 3D The structure of Embodiment 3 of the cell analysis component 400 of the combined detection card of the present invention is shown. The structure of the third embodiment is a further improvement on the basis of the structure of the second embodiment, which differs from the structure of the second embodiment in that:

[0103] In this embodiment, there are two test areas 4 located in the test cavity 2, which are respectively the first test area 41 and the second test area 42, and the two test areas are independent of each other (set at intervals) and connected, and the two test areas The test areas are connected by drainage area 6 . In this embodiment, the two test areas are rectangular, and the thicknesses are H 测1 、H 测2 , wherein the thickness H of the first test area 41 测1 Large, the detection surface formed by the liquid sample on the cavity side wall 3 in the first test area 41 has a large depth of field and a large sample carrying capacity pe...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a combined detection card for immunodetection and cell analysis and a combined detection method. According to the combined detection card, an immunodetection assembly and a cellanalysis assembly are integrated together through a shell structure formed by matching a bottom shell of the detection card with an upper cover of the detection card; the shell is provided with a first sample adding hole and a second sample adding hole which are used for adding samples to the immunodetection assembly and the cell analysis assembly respectively, a first interpretation window whichpenetrates out of an immunodetection area of the immunodetection assembly, and a second interpretation window and a third interpretation window which penetrate out of a detection face of the cell analysis assembly, which cooperate with a combined detection device for use; Immunodetection and cell analysis functions can be realized at the same time, and basic conditions are provided for POCT-levelsynchronous immunization and cell on-site joint inspection; according to the cell analysis assembly of the combined detection card, by arranging the sample injection notch, the vent hole and one or more test areas with different thicknesses, bubbles can be prevented from being generated, accurate control over the cell sample amount is achieved, and the cell counting precision and the typing detection precision are both considered.

Description

technical field [0001] The invention belongs to the technical field of biomedical detection, and in particular relates to a combined detection card for immunological detection and cell analysis and a combined detection method. Background technique [0002] In vitro diagnosis is the core of evidence-based medicine in Western medicine. It obtains the physical indications of the patient at that time through the detection of blood, urine, saliva and other body fluid samples of the patient, thereby providing an objective and clear quantitative basis for the doctor's diagnosis. With the development of science and technology, in vitro diagnosis has gradually moved from clinical laboratories and central laboratories to clinical departments of large hospitals such as emergency departments and ICUs, mobile medical carriers such as ambulances and patrol boxes, and multi-level diagnosis and treatment places such as second-level hospitals and community hospitals. Even went into the famil...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N15/14G01N21/78
CPCG01N15/1431G01N21/78G01N2015/1006
Inventor 李悦琴
Owner 苏州中科苏净生物技术有限公司