Anti-pruritus functional composition and preparation method and application thereof

A composition and anti-itching technology, applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc., to achieve the effects of resisting photoaging, regulating flora diversity, and strengthening skin barrier

Active Publication Date: 2020-12-01
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Due to the particularity of the skin of the elderly and the complexity of the causes of...

Method used

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  • Anti-pruritus functional composition and preparation method and application thereof
  • Anti-pruritus functional composition and preparation method and application thereof
  • Anti-pruritus functional composition and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Embodiment 1: A kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:

[0054] A. Weigh 2 parts of mussel extract, 7 parts of loquat leaf extract, 5 parts of saffron extract, 5 parts of tocotrienol, 3 parts of sclareolide, and pantethein by weight ratio 3 parts of calcium carbonate, 30 parts of β-cyclodextrin;

[0055] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 40% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 400 rpm for 20 minutes, and spray dry to obtain an anti-itching effect composition.

Embodiment 2

[0056] Embodiment 2: a kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:

[0057] A. Weigh 1 part of mussel extract, 2 parts of loquat leaf extract, 2 parts of saffron extract, 2 parts of tocotrienol, 1 part of sclareolide, and pantethein by weight ratio Calcium acid 1 part, β-cyclodextrin 20 parts;

[0058] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 20% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 300 rpm for 40 minutes, and spray dry to obtain an anti-itching effect composition.

Embodiment 3

[0059] Embodiment 3: a kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:

[0060] A. Weigh 5 parts of mussel extract, 5 parts of loquat leaf extract, 7 parts of saffron extract, 7 parts of tocotrienol, 2 parts of sclareolide, and pantethein by weight ratio Calcium acid 2 parts, β-cyclodextrin 25 parts;

[0061] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 30% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 350 rpm for 30 minutes, and spray dry to obtain an anti-itching effect composition.

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Abstract

The invention relates to an anti-pruritus functional composition and a preparation method and application thereof. The composition is characterized by consisting of the following components in parts by mass: 1-10 parts of a mussel extract, 2-7 parts of a loquat leaf extract, 2-7 parts of a crocus sativus extract, 2-7 parts of tocotrienol, 1-3 parts of sclareolide, 1-3 parts of calcium pantetheinesulfonate, and 20-30 parts of beta-cyclodextrin. The anti-pruritus functional composition prepared by the invention is good in stability, is safe and mild, can quickly and effectively improve the pruritus of the elderly through the synergistic interaction of the active ingredients, and also has the excellent beneficial effects of moisturizing, skin barrier strengthening, analgesia and stability, body odor removal, skin comfort improvement, and the like.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an anti-itching functional composition and its preparation method and application. Background technique [0002] Skin pruritus in the elderly is a neuropsychiatric skin disease. Because it seriously affects the health and quality of life of the elderly, it has received more and more attention in recent years, and it is urgent for the cosmetics industry to provide some comprehensive and reasonable solutions. The skin of the elderly has its unique characteristics: significantly reduced metabolic activity, significantly reduced sebum secretion, significantly worsened hydration and barrier function, frequent micro-inflammation, easily disordered skin surface flora, and susceptibility to certain environmental factors or diseases. Sensitivity has also increased significantly. Due to the lack of sebum, the skin is extremely dry, scaly and even finely cracked, resulting in itching, bu...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/9794A61K8/9789A61K8/67A61K8/49A61K8/46A61Q19/00A61P17/04
CPCA61K8/466A61K8/4973A61K8/673A61K8/678A61K8/987A61K2800/56A61K2800/592A61Q19/00A61K8/9789A61K8/9794A61P17/04
Inventor 王晓刘宇航毕永贤李亚男钱舒敏蒋丽刚
Owner PROYA COSMETICS
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