Abutment method for carbon dioxide incubator and isolator

Abstract

The invention discloses an abutment method for a carbon dioxide incubator and an isolator. The incubator comprises an outer box and an inner box, wherein during abutment, an inner flange ring and an outer flange ring are in sealing connection through a third air inflation sealing ring; a sterilization medium generation module is started to sterilize a sterilization space on an abutment position, and then, connection between an inner box door and an inner box abutment outlet as well as connection between an outer flange door and an outer flange ring can be cut off so as to open the outer flangedoor and the inner box door to transmit a culture dish; and the inner box door and the outer flange door are closed, a first air inflation sealing ring recovers connection between the inner box doorand the abutment outlet, the third air inflation sealing ring cuts off the connection between the inner flange ring and the outer flange ring, the incubator and the isolator are separated, an electricheating element in the outer box recovers to be started, and therefore, the inner box continuously carries out even heating. By use of the abutment method, the temperature in the incubator can be guaranteed to be even, and condensation can be effectively prevented from being formed on the inner side of the inner box door.

Description

technical field [0001] The invention relates to the technical field of aseptic transmission, in particular to a carbon dioxide incubator and a docking method with an isolator. Background technique [0002] The development and production of cell medicines related to gene therapy, stem cells, immune cell therapy, and tissue engineering have become an important direction for the future development of biomedicine. In the production of cell products, how to achieve the sterility of the process is the key to quality assurance. Since the sterility of cell products is verified through the final sterility test, there are shortcomings such as long time limit and low detection rate, so it is usually necessary to ensure the sterility of cell products through aseptic operation of the process. In the production process of sterile drugs such as cell products, it is often necessary to culture the original cells in an incubator. The incubator needs to maintain a constant culture temperature...

AI Technical Summary

Problems solved by technology

[0005] The first purpose of the present invention is to solve the problem of poor temperature uniformity in the existing RTP carbon dioxide incubator, provide a carbon dioxide incubator and a docking method with the isolator, which can ensure uniform temperature in the incubator, Effectively prevents condensation from forming on the inside of the inner door

[0006] The second purpose of the present invention is to solve the problem of poor connection reliability between the existing RTP carbon dioxide incubator and the isolator, and provide a carbon dioxide incubator and a docking method with the isolator, which can ensure that the inner box door and Reliable connection and sealing between outer flange doors, and simple structure and convenient operation

[0007] The third object of the present invention is to solve the existing RTP carbon dioxide incubator limited by the circular docking outlet, and the space utilization rate is low, to provide a carbon dioxide incubator and a docking method with the isolator, which can maximize Maximize the utilization of the internal space of the incubator to meet the needs of large-capacity / large-volume culture vessels

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