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Application of traditional Chinese medicine composition to preparation of medicine for preventing and treating diseases caused by atherosclerosis

A technology of atherosclerosis and composition, applied in the field of medicine, can solve the problems of complex syndrome differentiation and numerous causes, etc.

Inactive Publication Date: 2020-12-18
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] With the advancement of modern medical science and technology, people have a deeper understanding of coronary heart disease and stroke, but there are many causes of coronary heart disease and stroke, and the syndromes are more complicated. Therefore, using the rich experience and theory of traditional medicine in China, the development It will be the top priority of future research to develop targeted Chinese medicine preparations for the onset of disease and provide scientific basis for further improving clinical efficacy

Method used

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  • Application of traditional Chinese medicine composition to preparation of medicine for preventing and treating diseases caused by atherosclerosis
  • Application of traditional Chinese medicine composition to preparation of medicine for preventing and treating diseases caused by atherosclerosis
  • Application of traditional Chinese medicine composition to preparation of medicine for preventing and treating diseases caused by atherosclerosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Example 1 Preparation of Qilong Xuemaijian Granules

[0076] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0077] Coptidis 6, frankincense 12, myrrh 12, blood jellyfish 6, pinellia 9, whole gua lou 15, gynostemma 30, poria cocos 30, panshanlong 15, wherein, frankincense is frankincense fried with vinegar; myrrh is myrrh fried with vinegar;

[0078] 2) Wash the raw materials Coptis chinensis, frankincense, myrrh, Pinellia, Trichosanthes, Gynostemma, Poria cocos, and pangosaurus, put them in a Chinese medicine multifunctional extraction kettle and mix well, add tap water to soak for 30 minutes (usually 20-90 minutes), Wherein, the ratio of the weight of tap water added to the weight (dry weight) of the medicinal material mixture is 9:1 (usually 1-15:1);

[0079] 3) Turn on the power supply of the multifunctional extraction kettle for heating, heat to 100°C, keep at this temperature for constant temperature extraction for 3 hours, and th...

Embodiment 2

[0088] Preparation of Example 2 Qilong Xuemaijian Pills

[0089] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0090] Coptidis 3, frankincense 12, myrrh 6, blood dried fruit 3, pinellia 6, whole melon 9, gynostemma 15, poria cocos 15, pangosaurus 30

[0091] 2) After rinsing the medicinal materials Coptis chinensis, frankincense, myrrh, Pinellia, Gualou, Gynostemma pentaphyllum, Poria cocos, and pangosaurus, they were placed in a multifunctional extraction kettle of traditional Chinese medicine and mixed evenly, and then soaked in tap water for 60 minutes. The weight of the added tap water was equal to The weight (dry weight) ratio of the medicinal material mixture is 6:1;

[0092] 3) Turn on the power supply of the multi-functional extraction kettle for heating, heat to 80°C, keep at this temperature for constant temperature extraction for 5 hours, and then filter to obtain the first extraction solution for use;

[0093] 4) Then add tap wa...

Embodiment 3

[0098] Preparation of Example 3 Qilong Xuemaijian Tablets

[0099] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0100] Coptidis 9, frankincense 6, myrrh 12, dried blood 9, pinellia 9, whole melon 15, gynostemma 30, poria cocos 30, pangosaurus 10

[0101] 2) Wash the raw materials Coptis chinensis, frankincense, myrrh, Trichosanthes, Gynostemma, Poria cocos, and mountain dragon, put them in a multi-functional extraction kettle of traditional Chinese medicine, add tap water to soak for 20 minutes (usually 20-90 minutes), wherein, the added tap water The ratio of the weight to the weight of the medicinal material mixture (dry weight) is 12:1 (usually 1-15:1);

[0102] 3) Turn on the power supply of the multifunctional extraction kettle for heating, heat to 80°C, keep at this temperature for constant temperature extraction for 5 hours, and then filter to obtain the first extraction solution for use;

[0103] 4) Then add tap water to the filter...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition to preparation of a medicine or a health care product for preventing and treating diseases caused by atherosclerosis. The composition comprises the following raw materials of coptis chinensis, frankincense, myrrh, dragon's blood, rhizoma pinellinae praeparata, trichosanthes kirilowii maxim, gynostemma pentaphylla,poria cocos and dioscorea nipponica makino. The traditional Chinese medicine composition has the efficacy of reducing phlegm, promoting blood circulation, lowering turbidity and dredging collaterals,achieves the purpose of improving coronary heart diseases and stroke aiming at the important pathological mechanism of atherosclerosis in the development process of the coronary heart diseases and the stroke, has obvious curative effects of preventing, relieving and treating phlegm-blood stasis intermingled coronary heart diseases and the stroke, takes effects quickly, is small in toxic and sideeffects, is safe, efficient and stable pharyngitis treating medicine simple in preparation process, and is suitable for industrial production and easy to popularize. A new medicine source is providedfor preventing and treating phlegm-blood stasis intermingled coronary heart diseases, stroke and complications thereof.

Description

technical field [0001] The invention relates to the field of medicine, relates to a medicine or health food for treating coronary heart disease and apoplexy, in particular to the application of a traditional Chinese medicine composition in the prevention, alleviation and treatment of coronary heart disease and apoplexy medicine or health food. Background technique [0002] Atherosclerosis is the main cause of cardiovascular disease. According to the "China Cardiovascular Disease Report 2017", it is estimated that the number of coronary heart disease in my country is 11 million, and the number of stroke is 13 million. The number of patients will continue to grow rapidly and become a major public health problem. Sanitation problems, prevention and control are urgent. Lipid macrophage deposition in the subendothelial region is a hallmark of atherosclerosis, and lipid cells promote an inflammatory response in the arterial wall that may lead to multiple fatal pathological outcomes...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K36/896A61P9/10A23L33/105
CPCA61K36/718A61K36/324A61K36/328A61K36/889A61K36/896A61K36/8888A61K36/428A61K36/424A61K36/076A61K36/8945A61P9/10A23L33/105A23V2002/00
Inventor 胡元会崔翰明师帅张秋燕杜柏褚瑜光王欢邱志凌
Owner GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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