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Integrated reagent needle device

A reagent needle and integrated technology, which is applied in the field of sampling devices, can solve problems such as stability and safety defects, differences in film production effects, and low throughput, so as to improve operation stability, improve processing effects, and reduce residues Effect

Pending Publication Date: 2020-12-22
JIAXING JINGZHU BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional staining of exfoliated cells usually requires manual assistance, the uncertainty of manual operation will lead to differences in the effect of film production, and the additional contact between operators and samples will also bring risks, both in terms of stability and safety. defect
Existing devices for staining cells often have low throughput, cumbersome operation, and low efficiency, which often cannot meet the needs of institutions with large sample volumes.

Method used

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  • Integrated reagent needle device
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The invention provides an integrated reagent needle device, which includes a liquid injection needle 1 , a liquid suction needle 2 and a syringe 3 . The injection needle 1 is used for injecting reagents, including an injection section 11 into which the reagent enters, a discharge section 13 for discharging the reagent onto the glass slide, and an intermediate section 12 connecting the injection section 11 and the discharge section 13 . Preferably, the injection section 11 , the middle section 12 and the discharge section 13 form the injection needle 1 through integral molding. The liquid suction needle 2 is used to discharge the reagent waste liquid after the experiment is completed, including a liquid discharge section 21 for waste liquid discharge, a suction section 23 for absorbing waste liquid, and a communication section 22 connecting the liquid discharge section 21 and the suction section 23 . Preferably, the liquid outlet section 21 , the communication section 22...

Embodiment 2

[0035] This embodiment 2 is formed on the basis of embodiment 1, through the optimized design of the liquid suction needle structure in the device, the treatment effect of the device on waste liquid is improved. specifically:

[0036] A plurality of liquid-absorbing needles 2 are integrally installed in the syringe 3, and the plurality of liquid-absorbing needles 2 can simultaneously absorb waste liquid, which not only improves the absorption efficiency of waste liquid, but also further reduces the residual amount of waste liquid. Preferably, the ports of the suction section 22 are arranged horizontally. Here, the horizontal arrangement means that the suction port can be in flush contact with the surface of the glass slide, so that the waste liquid on the slide can be better absorbed. Further, the ports of the suction sections 22 of the plurality of liquid suction needles 2 are distributed along the circumferential direction, preferably evenly distributed along the circumfere...

Embodiment 3

[0040] Embodiment 3 is formed on the basis of Embodiment 1 or Embodiment 2. By adding a buffer device and a connecting device, the operation stability and installation convenience of the integrated cleaning device are improved. specifically:

[0041] A buffer device 4 is also provided in the integrated cleaning device, and the buffer device 4 includes a buffer plate 41 and a spring 42 . The spring 42 is installed on one end of the buffer plate 41 , and the spring 42 is elastically deformed along the vertical direction, and the vertical direction is the axial direction of the syringe 2 . The other end of the buffer plate 41 is connected to the needle cylinder 2, and the connection method of the two can be socketed, clamped, etc. When the cleaning needle 1 connected with the syringe 2 moves up and down during the cleaning operation, the spring 42 can play a rebound effect by using the inertia, forming a good buffering effect on the instantaneous impact force up and down, and pr...

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Abstract

The invention relates to an integrated reagent needle device in the technical field of sampling devices. The device comprises liquid injection needles, liquid suction needles and a needle cylinder; the liquid injection needle comprises an injection section, a middle section and a liquid discharge section, the liquid suction needle comprises a liquid outlet section, a communication section and a suction section, and the needle cylinder is of an open cylinder structure; the middle section and the communication section are connected into the needle cylinder, the injection section and the liquid outlet section are located on the outer side of the same end of the needle cylinder, and the liquid discharge section and the suction section are arranged on the outer side of the other end of the needle cylinder; and a port of the suction section is located below a port of the liquid discharge section, and a plurality of liquid injection needles are installed on the needle cylinder in an integrated mode. According to the device, the liquid injection needles and the liquid suction needles are integrated in the needle cylinder, the two actions of discharging and sucking can be combined into a whole, through the design of integrating the multiple liquid injection needles, the cleaning work of slides of different types can be completed without changing the action of the device, mechanical actions are omitted, the machine structure and program design can be simplified, and the cleaning efficiency is improved.

Description

technical field [0001] The invention relates to the technical field of sampling devices, in particular to an integrated reagent needle device. Background technique [0002] By observing the changes and abnormal phenomena of cells in various tissues of the human body, we can know whether there is a disease in the human body. Among them, cell preparation is the key to cytopathological detection. For example, the most common method for the diagnosis of female cervical or vaginal lesions is to take the exfoliated cells for staining and microscopic examination. [0003] The traditional staining of exfoliated cells usually requires manual assistance, the uncertainty of manual operation will lead to differences in the effect of film production, and the additional contact between operators and samples will also bring risks, both in terms of stability and safety. defect. Existing devices for staining cells often have low throughput, are cumbersome to operate, and have low efficienc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28B08B5/04
CPCG01N1/2813B08B5/04
Inventor 汪钰青朱海龟聂垒胡付余王扩业李一鸣陈石磊
Owner JIAXING JINGZHU BIOTECHNOLOGY CO LTD
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