Temperature control direct-writing nozzle of biological printer

Abstract

The invention discloses a temperature control direct-writing nozzle of a biological printer. The temperature control direct-writing nozzle comprises a Z-shaped plate, a quick plugging terminal, a heating copper pipe, an injector and a linear motion platform, wherein the linear motion platform is composed of a motor lead screw sliding block. The quick plugging terminal is matched with the Z-shapedplate and is fastened with the Z-shaped plate. An injection handle of an injector is fixed in the quick plugging terminal, the heating copper pipe and a thermistor are installed in an injector clamp,the heating copper pipe is packaged in the injector clamp by installing an injector clamp cap, an injection cylinder of the injector and the injector clamp are relatively fixed, and meanwhile the injector clamp is installed on the linear motion platform. During assembly, the central axis of the threaded hole in the quick plugging terminal coincides with the central axis of an injector assembly cavity in the injector clamp, and it is guaranteed that when the linear motion platform moves, the central axis of the injection handle of the injector coincides with the central axis of the injection cylinder. By means of the temperature control direct-writing nozzle, a hydrogel material can be stably shaped according to the set model at the set temperature and flow.

Description

technical field [0001] The invention belongs to the technical field of biomanufacturing, and in particular relates to a temperature-controlled direct-writing nozzle of a bioprinter. Background technique [0002] In recent years, bio-3D printing technology has flourished. Bioprinting technology is expected to be used in the construction of in vitro tissue models, and has broad prospects in tissue repair and drug testing. Among them, the direct-write bioprinting technology is widely used in the field of biomanufacturing due to its advantages of easy operation, low equipment price, and high cell survival rate. When direct-writing bio-3D printing technology manufactures in vitro tissue models, the materials usually used are various biocompatible hydrogel materials. Most of these hydrogel materials exhibit different rheological properties at different temperatures, which makes the hydrogel materials difficult to form or have low forming precision, and the manufactured in vitro ...

AI Technical Summary

Problems solved by technology

Most of these hydrogel materials exhibit different rheological properties at different temperatures, which makes the hydrogel materials difficult to form or have low forming precision, and the manufactured in vitro tissue models cannot be formed according to the designed model.

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