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A kind of hydrogel for assisting diet control and its preparation method and application

An auxiliary control and hydrogel technology, which is applied in the field of medical assistance, can solve the problems of small expansion rate and gel group volume affecting gastrointestinal digestion, etc., and achieve good collapse solubility and good satiety

Active Publication Date: 2021-12-14
吴良平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, methyl cellulose cannot evenly contact with water in the body. The outer layer absorbs water and swells into micelles, which will prevent water from entering the inner layer, resulting in a small expansion rate. It needs to be taken in large quantities to meet the functional requirements, and the formed gel group may have a large volume. affect gastrointestinal digestion

Method used

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  • A kind of hydrogel for assisting diet control and its preparation method and application
  • A kind of hydrogel for assisting diet control and its preparation method and application
  • A kind of hydrogel for assisting diet control and its preparation method and application

Examples

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Embodiment 1

[0041] This example is an embodiment of the hydrogel for assisting diet control of the present invention. The types of raw materials used in the hydrogel for assisting diet control in this embodiment and the amount of each raw material are shown in Table 1, which mainly consists of the following raw materials in parts by weight Cross-linked: 80.0 parts by weight of sodium carboxymethyl cellulose, 20.0 parts by weight of hydroxyethyl cellulose, and 1.0 parts by weight of citric acid; wherein the manufacturers and models of sodium carboxymethyl cellulose are shown in Table 2, and its DS ( The degree of substitution) is 0.7-1.2, and the viscosity of an aqueous solution with a mass concentration of 1% prepared by the sodium carboxymethylcellulose at 25°C is 5000-15000mPa·s; the manufacturer and model of hydroxyethylcellulose As shown in Table 2, the viscosity of the aqueous solution with a mass concentration of 2% prepared from the hydroxyethyl cellulose at 25° C. is 300-400 mPa·s....

Embodiment 2-7

[0054] Examples 2-7 are all one embodiment of the hydrogel for assisting diet control of the present invention. The types of raw materials used in these hydrogels for assisting diet control and the amount of each raw material are shown in Table 1. The preparation method is the same as in Example 1. Wherein used sodium carboxymethyl cellulose and water-soluble polysaccharide macromolecule producer and model are respectively as described in Table 2.

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Abstract

The invention discloses a hydrogel for assisting diet control, a preparation method and application thereof, and belongs to the technical field of medical assistance. The present invention uses sodium carboxymethyl cellulose, water-soluble polysaccharide macromolecule and polycarboxylic acid as raw materials to carry out cross-linking reaction to prepare a pH-sensitive hydrogel, and the obtained hydrogel can withstand acidic gastric juice and medium It can swell in the small intestinal fluid, and will collapse and dissolve in the alkaline colonic fluid. By controlling the amount of polycarboxylic acid and using non-ionic water-soluble polysaccharide polymers, the obtained hydrogel can withstand the acidic environment of the stomach. It has a higher swelling ratio. The hydrogel obtained in the invention can be used to prepare hydrogel capsules for assisting diet control, which is not only safe and harmless to the human body, but also has a very good feeling of satiety and does not affect the human body's nutrient absorption.

Description

technical field [0001] The invention belongs to the technical field of medical assistance, and in particular relates to a hydrogel for assisting diet control, a preparation method and application thereof. Background technique [0002] In 2016, the famous British medical journal "The Lancet" published a survey report on the weight of adults worldwide. The survey found that my country's obese population exceeded 90 million, surpassing the United States to become the country with the largest obese population in the world, including 43.2 million men and 46.4 million women, respectively. Accounting for 16.3% and 12.4% of the world. In the past few decades, obesity has become a global epidemic disease. Obesity will also be accompanied by complications, including diabetes, fatty liver, hypertension, coronary heart disease, sleep apnea syndrome, etc. Severe obesity may also induce myocardial Infarction and stroke seriously threaten people's health. At present, the main methods for ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08B15/10A23L33/00A23L29/20
CPCA23L33/00A23L29/20A23V2002/00A23V2200/228A23V2200/332A23V2250/51088A23V2250/51086A23V2250/032A23V2250/5108A23V2250/044A23V2250/02A23V2250/5024A23V2250/036A23V2250/056
Inventor 吴良平戴晓江黄红艳
Owner 吴良平