Alterations in endothelin receptors following hemorrhage and resuscitation by centhaquin

A technology of endothelin and receptor agonist, which is applied in cardiovascular system diseases, vector-borne diseases, and medical preparations containing active ingredients, etc. It can solve the problem of blood perfusion loss, hypothermia, immunosuppression, multiple organ failure and death in patients And other issues
CN112469474APending Publication Date: 2021-03-09MID WESTERN UNIVERSITY BIRENDRANAGAR +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
MID WESTERN UNIVERSITY BIRENDRANAGAR
Publication Date
2021-03-09

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Abstract

The present disclosure is related to methods and compositions for treating or preventing kidney injury or failure, comprising administering an endothelin B (ETB) receptor agonist and / or an alpha 2 adrenergic agent.
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Description

[0001] Cross References to Related Applications

[0002] This application claims priority under 35USC §119(e) to U.S. Provisional Patent Application No. 62 / 666,675, filed May 3, 2018, and Indian Application No. 201841019588, filed May 25, 2018, the disclosures of which are incorporated by reference in their entirety Incorporated into this article. technical field

[0003] The present disclosure relates to methods and compositions for treating or preventing renal injury or failure comprising administration of endothelin B (ET B ) receptor agonists and / or alpha 2 Adrenergic agent.

[0004] Incorporation by reference of electronically submitted materials

[0005] As a separate part of this disclosure, this application contains a Sequence Listing in computer readable form (Filename: 50000A_Seqlisting.txt; Size: 673 bytes; Created: May 2, 2019), which is hereby incorporated by reference in its entirety. Background technique

[0006] Hemorrhagic shock often results in inadequa...

Claims

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