Compositions, methods, and devices are herein disclosed for anti-
sneeze and
nose vestibule care for humans and other animals. An anti-
sneeze composition includes an
adrenergic agent, an anticholinergic agent, an
antihistamine, a
plasticizer for
nose skin /
nose muscle, and a soothing agent. A version of nose
vestibule care composition includes alternative functional agents, such as anti-inflammatory agents, anti-oxidants, and antimicrobials, besides
adrenergic, anticholinergic, and
antihistamine agents. The alternative or additional agents are present in the invented composition for the purposes of wellness care of noses, prevention of diseases or aiding a
medical treatment. The methods and devices for delivering the compositions to the nose vestibules for anti-
sneeze, for wellness care, preventive care measure against diseases, and for aiding
medical treatment of diseases are prescribed.