Synthetic method of dichloropentachloromethylthiazole

Abstract

The invention discloses a synthetic method of dichloropentachloromethylthiazole, and relates to the technical field of dichloropentachloromethylthiazole preparation, and the dichloropentachloromethylthiazole synthesis method specifically comprises the following operation steps: S1, carrying out dichloropentachloromethylthiazole synthesis; s2, carrying out solid-liquid separation; s3, carrying outsolid waste residue treatment; s4, carrying out distillation and extraction; s5, carrying out heating and degassing; s6, carrying out hydrogen chloride recovery; and S7, carrying out secondary utilization of waste residues. According to the dichloropentachloromethylthiazole synthesis method, the residual distillable solution in the solid waste residues can be recycled by collecting and extruding the filtered solid waste residues, so that resource waste is avoided, and the yield of a dichloropentachloromethylthiazole finished product is increased; the distilled solution is subjected to degassing operation, so that a NaHCO3 solution or water is not required to be used for washing and neutralizing a hydrogen chloride component in a semi-finished product, the generation of wastewater is avoided, the long-term purchase of additional materials is avoided, the production cost is reduced, and the economic benefit is improved.

Description

technical field [0001] The invention relates to the technical field of preparation of dichloropentachloromethylthiazole, in particular to a synthesis method of dichloropentachloromethylthiazole. Background technique [0002] Dichloropentachloromethylthiazole is used in the synthesis of pesticides thiamethoxam, clothianidin, and pharmaceutical ritonavir. Thiamethoxam, as a new generation of As the inhibitor of human immunodeficiency virus (HIV), Wei is also indispensable in the absence of specific drugs. Both of them have good market prospects, so the preparation and synthesis methods of dichloropentachloromethylthiazole are attracting more and more attention. attention. [0003] The synthesis method of dichloropentachloromethylthiazole is usually to add 2-chloropropenyl isothiocyanate and solvent chloroform in a reaction flask, then add sulfuryl chloride dropwise for reaction, and filter and distill after the reaction to obtain dichloropenta The semi-finished product of ch...

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies in the prior art, the present invention provides a method for synthesizing dichloropentachloromethylthiazole, which solves the problem that the existing method for preparing dichloropentachloromethylthiazole in the above-mentioned background technology will realize solid-liquid Separation, a certain amount of distillable solution remains in the solid waste residue. This part of the distillable solution cannot be recycled, resulting in a waste of resources and a reduction in the output of finished dichloropentachloromethylthiazole.