Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence

A nano-zinc oxide and stem cell technology, applied in the field of stem cell essence and its preparation, can solve the problems of human health hazards, poor chemical stability, toxicity and carcinogenicity, etc., achieve excellent antibacterial performance, extend shelf life, and repair damaged skin tissue Effect

Pending Publication Date: 2021-03-26
ZHENGZHOU UNIV +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, daily-use cosmetics are rich in nutrients and are particularly prone to breed microorganisms. In addition to changing the color, aroma and taste of cosmetics, pathogenic microorganisms and their metabolites can also cause harm to human health
At present, there are many broad-spectrum antibacterial substances used in cosmetics, but there are some fatal problems, such as poor chemical stability

Method used

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  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence
  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence
  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence

Examples

Experimental program
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Example Embodiment

[0029]Example 1 Preparation of hydrophilic zinc oxide quantum dots

[0030]Synthesis of hydrophilic zinc oxide quantum dots: Take 35 mm potassium hydroxide to 50 ml of beaker, add 20 ml of waterless ethanol to stir 15 min until the potassium hydroxide is completely dissolved, and placed in a refrigerator at 4 ° C. The zinc and dihydride of 25 mM acetate was added to a single flask of 15 ml of anhydrous ethanol, and stirred back and reflux at 80 ° C until zinc acetate was completely dissolved (2h), followed by placing the mixture in an ice bath. The ethanol solution of potassium hydroxide is added dropwise to a single-mouth flask which is in a zinc acetate ethanol solution, and stirring is continuously reacted for 30 min. At this point, the reaction solution is observed by clarifying turbidity and gradually clarifying. When the reaction mixture was taken out to the ice bath to be tempeared to room temperature, 1.5 ml of deionized water and 500 ul3-aminopropyltriethoxysilane (APTES) mixe...

Example Embodiment

[0046]Example 2 Preparation of hydrophilic nano zinc oxide stem cell essence

[0047]The hydrophilic zinc oxide quantum dots prepared using Example 1 were prepared by hydrophilic nano-zinc oxide stem cell essence, and the production process isfigure 1 As shown, using the following steps:

[0048](1) We can weigh the components according to the formulation: 60% (volume / volume) of stem cell conditions, 3% (volume / volume) of glycerol, 0.6% (mass / volume) of hydrophilic nano zinc oxide, aloe vera extraction 0.25% (mass / volume), collagen extract 2% (mass / volume), 0.5% (mass / volume) of pearl hydrolyzate, 0.5% (mass / volume), trieletol 0.5% (quality / Volume), 20.5% (mass / volume), 4% (mass / volume) of hyaluronate, 2.5% (mass / volume), 0.5% (mass / volume), glutinous mixture Sugar 0.5% (mass / volume), glycyrrusted pirates 0.5% (mass / volume), and margin is purified;

[0049](2) Clean the capacity bottle clean, pure water, 121 ° C, high pressure steam sterilization for 30 min; then ...

Example Embodiment

[0052]Example 3 Preparation of hydrophilic nano zinc oxide stem cell essence

[0053]The hydrophilic zinc oxide quantum dots prepared using Example 1 were prepared by hydrophilic nano-zinc oxide stem cell essence, and the production process isfigure 1 As shown, using the following steps:

[0054](1) We can weigh the components according to the formulation: 50% (volume / volume) of stem cell conditions, 2% (volume / volume) of glycerol, 0.4% (mass / volume), aloe vera extraction 0.5% (mass / volume), collagen extract 5% (mass / volume), 0.8% (mass / volume) of pearl hydrolyzate, 0.8% (mass / volume), triethoxide 0.8% (quality / Volume), 20.7% (mass / volume), 6% (mass / volume) of hyaluronate, 3% (mass / volume), 0.7% (mass / volume), pantonol Sugar 0.8% (mass / volume), glycyrrigate pirates 0.7% (mass / volume), and margin is purified;

[0055](2) Clean the capacity bottle clean, pick up the pure water, 121 ° C, high pressure steam sterilization for 30 min; then add aqueous powder raw materi...

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Abstract

The invention provides stem cell essence containing hydrophilic nano-zinc oxide. Based on the characteristic that the stem cells repair the skin tissues, complex factors secreted by the stem cells canbe stored in the skin tissues for a long time, play a role in regulating and repairing the skin cells through skin microcirculation regulation of the human body, eliminate free radicals, prevent oxidation, diminish inflammation and promote tissue regeneration. According to the stem cell essence containing the hydrophilic nano-zinc oxide, added hydrophilic zinc oxide quantum dots show infrared spectrum absorption peaks at 3425 cm<-1>, 2936 cm<-1>, 1574 cm<-1>, 1405 cm<-1>, 1018 cm<-1> and 525 cm<-1> and have obvious destructiveness on staphylococcus aureus and escherichia coli, so that the cell walls of the treated bacteria are shrunk and seriously damaged; and meanwhile, the hydrophilic zinc oxide quantum dots also have an obvious inhibiting effect on enterococcus faecium, bacillus cereus, bacillus megaterium and micrococcus luteus, so that the antibacterial property is excellent, and the shelf life of a product is effectively prolonged. The preparation method is simple and suitable for industrial production.

Description

technical field [0001] The invention relates to a stem cell essence containing hydrophilic nanometer zinc oxide and a preparation method thereof, belonging to the technical field of cosmetics. Background technique [0002] With the improvement of living standards, anti-aging has become a topic of concern to more and more people. Anti-aging products continue to experience strong growth, with more than half of the market focused on anti-aging products that delay or reduce the effects of aging, according to Kline, a world-renowned consultancy and research firm. Stem cells are one of the most attractive fields in modern biology and medicine, and are an important direction of life science research. Mesenchymal stem cells have great advantages as the seed cells of stem cell anti-aging products. They have a wide range of sources, are easy to isolate and culture, have huge potential for in vitro expansion, and have unique immunological characteristics. They have the potential to be...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/27A61K8/34A61K8/42A61K8/49A61K8/63A61K8/65A61K8/73A61K8/81A61K8/9794A61K8/98A61Q17/00A61Q19/00A61Q19/08C01G9/02B82Y40/00B82Y30/00
CPCA61K8/99A61K8/27A61K8/9794A61K8/65A61K8/987A61K8/8147A61K8/4946A61K8/735A61K8/982A61K8/345A61K8/42A61K8/73A61K8/63A61Q19/08A61Q19/00A61Q17/005C01G9/02B82Y30/00B82Y40/00A61K2800/413C01P2004/64C01P2004/04C01P2004/10
Inventor 刘凯凯赵文博高萧芳赵辉单崇新
Owner ZHENGZHOU UNIV
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