Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Use of lycium barbarum polysaccharides in preparation of medicines for dilatating thoracic aorta

A technology of thoracic aorta and wolfberry polysaccharide, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc.

Pending Publication Date: 2021-04-02
NINGXIA MEDICAL UNIV
View PDF4 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, whether Lycium barbarum polysaccharide can enhance the expression of Keap1 / Nrf2 anti-oxidative stress signaling pathway in cardiovascular endothelial cells, improve the antioxidant capacity of cardiovascular endothelium, improve the body's oxidative stress state, and then achieve the function of protecting the cardiovascular system Research not reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Use of lycium barbarum polysaccharides in preparation of medicines for dilatating thoracic aorta
  • Use of lycium barbarum polysaccharides in preparation of medicines for dilatating thoracic aorta
  • Use of lycium barbarum polysaccharides in preparation of medicines for dilatating thoracic aorta

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0022] The first group of experiments (detection of transfection efficiency)

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses use of lycium barbarum polysaccharides in preparation of medicines for dilatating a thoracic aorta. According to the lycium barbarum polysaccharides, the action of protecting acardiovascular system is exerted through improving expression of an oxidative-stress-resisting signal channel protein PKeap1 / Nrf2, improving blood vessel endotheliocyte oxidative stress injury induced by Ang II (angiotensin II) and then improving an oxidative-stress-resisting state of the cardiovascular system. Simultaneously, the lycium barbarum polysaccharides further play a role in reducing inflammation causing factors.

Description

technical field [0001] The invention belongs to the field of cardiovascular diseases, and in particular relates to the use of Lycium barbarum polysaccharide in the preparation of thoracic aorta diastolic medicine. Background technique [0002] The Keap1 / Nrf2 pathway plays a vital role in improving the body's total antioxidant capacity, anti-apoptosis, anti-tumor, anti-inflammatory response, and neuroprotection. However, excessive oxidative stress leads to an imbalance in the regulation level of the oxidative system and the antioxidant system in the body. At this time, the damage effect of oxidative stress on tissue cells is more significant, while the anti-oxidative stress pathway is in a state of relative inhibition. [0003] Lycium barbarum, as a kind of traditional Chinese medicine with both food and medicine, is favored by people for its special effects such as nourishing the lungs and relieving cough, nourishing the liver and improving eyesight. Lycium Barbarum Polysac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/715A61P9/00A61P9/08
CPCA61K31/715A61P9/00A61P9/08
Inventor 朱玲勤耿瑶穆乐高媛媛薛姝婧李光华
Owner NINGXIA MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com