Preparation method of vitamin-B buccal tablets and chewable tablets

A technology of B vitamins and chewable tablets, which is applied in the direction of food science, can solve the problems of large amount of sweeteners, heavy bitterness, and low content of B vitamins, and achieve the effect of improving the taste

Pending Publication Date: 2021-04-20
石药集团中诺药业(泰州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] B vitamins include 8 vitamins including vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacinamide, pantothenic acid, folic acid and biotin. B vitamins can produce many beneficial effects: first, promote the three major products of sugar, fat and protein Second, it can produce the nutrients needed for hematopoiesis, help digestion and absorption, promote the detoxification ability of the liver, relieve the pressure of the body, make people energetic, relieve fatigue, and play a role The effect of hangover and detoxification, thirdly, it can mainta

Method used

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  • Preparation method of vitamin-B buccal tablets and chewable tablets
  • Preparation method of vitamin-B buccal tablets and chewable tablets

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0046]Example 1

[0047]The content of each component of each 1000 species is: a hydrochloride 2g, riboflavin 2g, piP polyol 2g, vitamin B12 (1%) 0.2 g, nicotinamide 50g, ferric acid 0.4 g, biotin (1% 8g, D-pantothenate 17g, sorbitol 658.4g, water-water citric acid 24g, stearate 16g, hydroxypropylttellulose 10g, Aspen 2G, Huanghuoxia 8g;

[0048]Step 1: Niatoramide sustained release granules prepare

[0049]1) Weigh the nicotinamide 100g, sorbitol 354g, water-water citric acid, 20g of hydroxyproplatocellulose 20g, Pasin 2g, is placed in a wet mixed granulator, stirring at a wet mixed granulator Set to 600 rpm, the chopping speed is set to 1200 rpm, mix 5 min, then add 70% of ethanol to make a wetting agent, the addition amount can be completely wetted, the stirring speed is set to 600 rpm, the chopper speed is set to 1200 rpm, granulation The time is set to 100s, and then the dried drying case is set to 40 ° C, and the mixed material is dried, and the particle water content is ≤4%, then the ...

Example Embodiment

[0060]Example 2

[0061]Each 1000 pieces of components are: phrymitus 8g, riboflavin 7g, piP polyol, vitamin B12 (1%) 0.2 g, nicotinamide 36g, folic acid 0.4 g, biotin (1% ) 8g, D-flue-ingolic acid 14g, sorbitol 883.5g, stearate 20g, hydroxypropyl tincellulose 5.4g, Aspen 1.5g, corn flavor 8g;

[0062]Step 1: Niatoramide sustained release granules prepare

[0063]1) Take 1G Aspen in 10 g of 70% ethanol solution to prepare a solution of 70% ethanol solution, spare.

[0064]2) Weigh the nicotinamide 72g, sorbitol 176.2 g, hydroxyproplatocellulose, 10.8 g of hydroxyproplactyl alcohol, and the stirring speed is set to 600 rpm, chopped speed 1200 rpm, mixed speed Time is 5 min, add the Aspen 70% ethanol solution, and the stirring speed is set to 600 rpm, the chopping speed is 1200 rpm, the grain time is 100s, then drying with a blast dryer at 40 ° C, drying to the particle water content ≤4%, granulated by 40 mesh, over 40 mesh, 80 mesh sieve to obtain 343 g of 40 to 80 mesh smoke amide sustained rel...

Example Embodiment

[0075]Example 3

[0076]The content of each component of each 1000 species is: a thiosamine hydrochloride 7g, riboflavin 7g, piP polyol, vitamin B12 (1%) 0.2 g, nicotinamide 40g, ferric acid 0.4 g, biotin (1% 4G, D-pantherdate 12g, sorbitol 1086.9g, magnesium stearate 24g, hydroxypropylttellulose 2g, Aspen 1.5g, wheat fragrant sperm 8g.

[0077]Step 1: Niatoramide sustained release granules prepare

[0078]1) Take 4 g of hydroxypropylttellulose in 40 g of 85% ethanol solution to prepare a solution of hydroxyproxylketolane 85% ethanol solution, spare;

[0079]2) Weighted the nicotinamide 80g after 80 mesh sieve, 316 g of sorbitol, sequentially placed in a wet mixed granulator, the stirring speed is set to 600 rpm, the chopper speed is 1200 rpm, the mixture is 5 min, then hydroxypropion The melamine is 85% ethanol solution, the stirring speed is set to 600 rpm, the chopper speed is 1200 rpm, the grain time is 100s, then dried with a 40 ° C blast drying case, dry until the particle water content i...

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Abstract

The invention discloses a preparation method of vitamin-B buccal tablets and chewable tablets, and belongs to the technical field of health foods. The preparation method of the vitamin-B buccal tablets and chewable tablets comprises the following steps of preparing vitamin B and auxiliary materials. According to the vitamin-B buccal tablets or chewable tablets, a food processing taste masking technology and a pharmaceutical preparation slow release technology are organically combined and applied, and the prepared vitamin-B buccal tablets or chewable tablets have the characteristic of sugar-free slow release, can be rich in a large amount of vitamin-B, particularly can be rich in nicotinamide with relatively heavy bitterness, and can well mask the bitterness of the nicotinamide; and therefore, the taste of the vitamin-B buccal tablets and chewable tablets is effectively improved, and the absorption effect of the product is not influenced.

Description

technical field [0001] The invention belongs to the technical field of health food, in particular to a method for preparing B vitamin buccal tablets and chewable tablets. Background technique [0002] B vitamins include 8 vitamins including vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacinamide, pantothenic acid, folic acid and biotin. B vitamins can produce many beneficial effects: first, promote the three major products of sugar, fat and protein Second, it can produce the nutrients needed for hematopoiesis, help digestion and absorption, promote the detoxification ability of the liver, relieve the pressure of the body, make people energetic, relieve fatigue, and play a role The effect of hangover and detoxification, thirdly, it can maintain the normal work of the nervous system and the nutrients needed for health, can effectively prevent atherosclerosis, reduce the generation of coronary atherosclerotic plaque, and can also enhance fat and Cholesterol metabolism; am...

Claims

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Application Information

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IPC IPC(8): A23L33/15A23L33/125A23L33/10A23L5/20
Inventor 武运浦张瑞国吴慧星许乐
Owner 石药集团中诺药业(泰州)有限公司
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