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Compound for enhancing immune function and improving intestinal morphology and application thereof

A technology that enhances immunity and compounds, applied in applications, animal feed, additional food elements, etc., can solve problems such as prone to diarrhea, increased bacterial resistance, loss of farm production benefits, etc., to protect the structure and function of the intestinal tract growth, improving feed utilization, and alleviating the effects of external stress

Pending Publication Date: 2021-04-30
FUJIAN AONONG BIOLOGICAL TECH GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Under intensive and large-scale breeding conditions, animals are stressed due to feeding density, immunization, virus infection, fright, etc., and they are prone to physiological problems such as diarrhea and intestinal flora imbalance, which seriously affect the growth and development of animals and cause production problems. Reduced performance and meat quality, causing huge losses to the production efficiency of the farm
Although antibiotics can alleviate the above situation, they will cause the disorder of animal intestinal flora, enhance bacterial resistance, reduce animal immunity, cause inflammation or side effects, and seriously affect the quality and food safety of animal products, indirectly endangering human beings health, but also caused drug residues and environmental pollution

Method used

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  • Compound for enhancing immune function and improving intestinal morphology and application thereof
  • Compound for enhancing immune function and improving intestinal morphology and application thereof
  • Compound for enhancing immune function and improving intestinal morphology and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0031] Using a single factor design, select health status, body weight close to the outer triple "Du grew up", body weight of 270 healthy growing pigs of 10.5 ± 0.5kg, randomly divided into 9 treatment groups (3 repetitions for each treatment group, 10 pigs for each repetition), respectively control group 1 (blank control group), control group 2 (chlortetracycline control group), control group 3-5 (composite control group) and embodiment group 1-4. Wherein, control group 2 adds aureomycin to basal ration (referring to U.S. NRC (2012) pig nutrient requirements), and control group 3-5 and embodiment group 1-4 add aureomycin respectively to basal ration (referring to U.S. NRC (2012) Nutritional requirements of pigs) by adding the corresponding compound.

[0032] The composition of the basal diet is shown in Table 1, and the composition of the compound in each group is shown in Table 2.

[0033] Table 1 basal diet composition (unit: wt%)

[0034] Diet Composition Cont...

Embodiment 5

[0052] A compound for enhancing immune function and improving intestinal morphology, the compound comprising the following components and contents by weight: 6 parts of gamma-aminobutyric acid fumarate, 0.5 parts of galactooligosaccharides, sodium L-ascorbate 0.4 parts, 3 parts of sterol ester, 3 parts of curcumin and 8 parts of alanyl glutamine dipeptide.

[0053] The preparation method of the complex is: after mixing galactooligosaccharides and L-sodium ascorbate, adding γ-aminobutyric acid fumarate, sterol ester, curcumin, and alanyl glutamine dipeptide in sequence, Mix evenly to get the compound.

[0054] When applied, the compound is added to the basal ration, and the addition ratio of the compound in the basal ration is 0.5 wt%.

Embodiment 6

[0056] A compound for enhancing immune function and improving intestinal morphology, the compound comprising the following components and contents by weight: 8 parts of gamma-aminobutyric acid fumarate, 0.3 parts of galactooligosaccharides, sodium L-ascorbate 0.6 parts, 1 part of sterol ester, 5 parts of curcumin and 6 parts of alanyl glutamine dipeptide.

[0057] The preparation method of the complex is: after mixing galactooligosaccharides and L-sodium ascorbate, adding γ-aminobutyric acid fumarate, sterol ester, curcumin, and alanyl glutamine dipeptide in sequence, Mix evenly to get the compound.

[0058] When applying, the compound is added to the basal ration, and the addition ratio of the compound in the basal ration is 2wt%.

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Abstract

The invention relates to a compound for enhancing immune function and improving intestinal morphology and application thereof. The compound comprises the following components in parts by weight: 5-9 parts of gamma aminobutyric acid fumarate, 0.2-0.5 part of galactooligosaccharide, 0.25-0.75 part of sodium ascorbate, 1-3 parts of sterol ester, 2-5 parts of curcumin or modified curcumin and 5-9 parts of alanyl glutamine dipeptide. During application, the compound is added into basic ration. Compared with the prior art, the feed additive has the advantages that the immune function of animals is enhanced from multiple dimensions of oxidation resistance, stress resistance, immune activation and the like, the morbidity is reduced, the intestinal tract form is improved, the growth potential and the feed utilization rate are improved, no toxic or side effect exists, no drug resistance exists, antibiotics can be replaced, and the feed additive has a good application prospect.

Description

technical field [0001] The invention belongs to the technical field of animal feed, and relates to a compound for enhancing immune function and improving intestinal morphology and application thereof. Background technique [0002] Under intensive and large-scale breeding conditions, animals are stressed due to feeding density, immunization, virus infection, fright, etc., and they are prone to physiological problems such as diarrhea and intestinal flora imbalance, which seriously affect the growth and development of animals and cause production problems. The performance is reduced, and the meat quality is reduced, causing huge losses to the production efficiency of the farm. Although antibiotics can alleviate the above situation, they will cause the disorder of animal intestinal flora, enhance bacterial resistance, reduce animal immunity, cause inflammation or side effects, and seriously affect the quality and food safety of animal products, indirectly endangering human being...

Claims

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Application Information

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IPC IPC(8): A23K20/163A23K20/105A23K20/174A23K20/121A23K20/168A23K20/111A23K20/147
CPCA23K20/163A23K20/105A23K20/174A23K20/121A23K20/168A23K20/111A23K20/147
Inventor 肖丽萍周盛昌苏建民陈志敏丁能水吴有林
Owner FUJIAN AONONG BIOLOGICAL TECH GRP CO LTD
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