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Mongolian medicine six-ingredient elecampane granules and preparation method thereof

A technology of woody incense and granules, which is applied in the direction of medical formula, antipyretics, drug combinations, etc., can solve the problems of difficult extraction of medicinal ingredients, strong irritation of the pharynx and esophagus, and restrictions on the development and application of Mongolian medicine. It is not easy to achieve Moisture-absorbing and moldy, easy to absorb, and high in taking compliance

Inactive Publication Date: 2021-04-30
内蒙古祈蒙药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The dosage is inaccurate, the process is simple, and the raw materials are only crushed and mixed, resulting in the finished product tastes bitter, spicy, pungent, sour, large amount, strong irritation to the pharynx and esophagus, and difficult to swallow, which leads to the fear of difficulty in taking the medicine. , especially not conducive to children's medication, greatly reducing the compliance of medication, "difficult to drink" seems to have become synonymous with Mongolian medicine, which also restricts the development and application of Mongolian medicine to some extent
[0003] Although the preparation methods of traditional decoctions, powders and capsules are simple and easy, they need to be prepared before use. If they are left for a long time, they are prone to mold and deterioration, and they are inconvenient to carry. If the patient goes out, it is inconvenient to take the medicine. , especially children are difficult to take, and the fat-soluble and insoluble ingredients in the medicinal materials are not easy to extract completely

Method used

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  • Mongolian medicine six-ingredient elecampane granules and preparation method thereof
  • Mongolian medicine six-ingredient elecampane granules and preparation method thereof
  • Mongolian medicine six-ingredient elecampane granules and preparation method thereof

Examples

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preparation example Construction

[0030] In addition, the present invention also provides a preparation method of Mongolian medicine Liuwei Muxiang granules, which comprises the following steps: grinding and pulverizing raw materials except auxiliary materials to obtain coarse powder, and then sterilizing the coarse powder and sieving for the first time to obtain refined powder , the refined powder and auxiliary materials are mixed into the granulator and mixed to make a soft material. The soft material is granulated, dried, granulated and sieved twice, and then placed in a mixer for mixing to obtain the Mongolian medicine Liuweimu Fragrant granules. The preparation method of the Mongolian medicine Liuwei Muxiang granules does not include the steps of decocting, concentrating, and extracting in traditional powders and decoctions, which simplifies the operation steps and avoids the medicinal properties of the medicinal materials in the process of decocting, concentrating, and extracting. Loss or denaturation of...

Embodiment 1

[0041] This example provides a kind of Mongolian medicine Liuwei Muxiang granules, including: 150g of Muxiang, 100g of gardenia, 50g of pomegranate, 50g of mangosteen flower, 50g of cardamom, 50g of longicorn, 150g of sucrose and 100g of starch.

[0042] The preparation of the Mongolian medicine Liuwei Muxiang granules includes: grinding and pulverizing raw materials other than sucrose and starch to obtain coarse powder, then heating the coarse powder to 50° C., keeping the temperature for 1 hour, and passing through a 100-mesh sieve to obtain refined powder. Mix the refined powder and sucrose into the wet mixing granulator and mix for 25 minutes. During this period, add 10% starch slurry made from starch and make soft material. When the soft material is held by hand, it will disperse The soft material can be taken out. Pass the soft material through a 12-mesh sieve to obtain wet granules, and dry the wet granules in an oven at 50°C for 2 hours to obtain dry granules. Put the...

Embodiment 2

[0044] This example provides a kind of Mongolian medicine Liuwei Muxiang Granules, including: 250g of Muxiang, 200g of Gardenia, 150g of Pomegranate, 150g of Pomegranate, 150g of Cardamom, 150g of Piper longum, 200g of sucrose, 100g of starch, 10g of flavoring agent, disintegrant Solution 10g and wetting agent 30g.

[0045] The preparation of the Mongolian medicine Liuwei Muxiang granule includes: grinding and pulverizing raw materials except sucrose and starch to obtain coarse powder, then heating the coarse powder to 60° C., keeping the temperature for 3 hours, and passing through a 100-mesh sieve to obtain refined powder. Refined powder is mixed with sucrose, flavoring agent, disintegrating agent and wetting agent and added to the wet mixing granulator and mixed for 35 minutes. During this period, 10% starch slurry made from starch is added to make soft material. When soft material Hold it into a ball with your hand, and when you let go of it, you can take out the soft mate...

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Abstract

The invention provides Mongolian medicine six-ingredient elecampane granules and a preparation method thereof, and relates to the technical field of Mongolian medicines. The Mongolian medicine six-ingredient elecampane granules are prepared from the following raw materials: elecampane, fructus gardeniae, pomegranate, flos rhododendri mollis, fructus amomi rotundus, fructus piperis longi and auxiliary materials. The auxiliary materials capable of improving the taste of the original six-ingredient elecampane powder are adopted, the medicine effect of the original six-ingredient elecampane powder is not influenced, and the taking compliance of a patient is enhanced. In addition, the invention also provides a preparation method of the Mongolian medicine Liuwei elecampane granules, which comprises the following steps: grinding and crushing the raw materials except the auxiliary materials to obtain coarse powder, sterilizing and primarily screening the coarse powder to obtain refined powder, mixing the refined powder with the auxiliary materials, adding the mixture into a granulator, and uniformly mixing to obtain a soft material, granulating, drying, straightening and secondarily sieving the soft material, and mixing in a mixer to obtain the Mongolian medicine six-ingredient elecampane granules. The Mongolian medicine six-ingredient elecampane granules not only can ensure that the drug properties in the medicinal materials are not easy to lose, but also are convenient to take and quick to absorb.

Description

technical field [0001] The invention relates to the technical field of Mongolian medicine, in particular to a Mongolian medicine Liuwei Muxiang granule and a preparation method thereof. Background technique [0002] Liuwei Muxiang Powder is recorded in the 2015 edition of the Pharmacopoeia of the "Chinese Pharmacopoeia", and it is an empirical prescription of Mongolian medicine. The technical feature of the original preparation is that all the medicinal materials in the prescription are directly crushed and packaged. The dosage is inaccurate, the process is simple, and the raw materials are only crushed and mixed, resulting in the finished product tastes bitter, spicy, pungent, sour, large amount, strong irritation to the pharynx and esophagus, and difficult to swallow, which leads to the fear of difficulty in taking the medicine. , especially not conducive to children's medication, which greatly reduces the compliance of medication, and "difficult to drink" seems to be syn...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/16A61K47/36A61P29/00
CPCA61K9/1652A61K36/185A61K36/285A61K36/45A61K36/67A61K36/744A61K36/9064A61P29/00A61K2300/00
Inventor 那生桑王玉华宋宏春冯立宝王亚辉徐佳枫
Owner 内蒙古祈蒙药业股份有限公司
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