Preparation method of magnetic nanowire

Abstract

The invention discloses a preparation method of a magnetic nanowire, and belongs to the field of nervous system repair and nano-structure preparation. The preparation method of a magnetic nanowire comprises the following steps: 1, synthesizing magnetic nanoparticles with ferroferric oxide cores and a silicon dioxide coating; 2, constructing a static magnetic field, and the direction of the static magnetic field can be regulated and controlled at any angle in a two-dimensional plane; and 3, dropping the magnetic nanoparticles monodispersion liquid containing the Matrigel matrigel onto a slide in the static magnetic field, assembling the magnetic nanoparticles through the static magnetic field to form the magnetic nanowire, and fixing the linear structure of the magnetic nanowire through the Matrigel matrigel.

Description

Technical field [0001] The present invention relates to the repair of nervous system and the field of nanostructures, and more particularly to a magnetic nanowire preparation method. Background technique [0002] Stem cell transplantation has become an important means of treating nervous system damage and neurodegenerative diseases, but randomized growth of neuronal neurons differentiated by the transplanted stem cells, so that it is not effective to contact the target cells and form a synaptic connection, has become stem cells Major scientific issues faced by transplantation therapy. The existing biomaterial for induction of neurons, including nanofibers, anisotropic hydrogel, and the like can only be able to achieve a unilateral directional growth of neurons, and cannot accommodate complex thermal repair environments. Inventive content [0003] In response to the shortcomings of the prior art, the present invention proposes a method of preparing a magnetic nanowire. [0004] T...

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Problems solved by technology

[0002] Stem cell transplantation therapy has become an important means for the treatment of nervous system injury and neurodegenerative diseases, but the random growth of newborn neuron neurites differentiated by transplanted stem cells, so that they cannot effectively contact with target cells and form synaptic connections, has become Major scientific issues facing transplantation therapy

Existing biomaterials used to induce directional growth of neurons, including nanofibers, anisotropic hydrogels, etc., usually can only induce the growth of neurons in a single direction, and cannot adapt to the complex repair environment of the nervous system

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