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An automated device for effectively enriching neurogenic exosomes in blood

A technology of automated equipment and exosomes, applied in the field of medical devices, can solve problems such as ineffectiveness, achieve the effect of simple and convenient process, and reduce the space occupied by equipment

Active Publication Date: 2022-02-11
北京凯祥弘康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The present invention aims at the problem that there is no effective and rapid enrichment equipment for neurogenic exosomes in blood in the prior art, and provides an automatic equipment for effectively enriching neurogenic exosomes in blood

Method used

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  • An automated device for effectively enriching neurogenic exosomes in blood
  • An automated device for effectively enriching neurogenic exosomes in blood
  • An automated device for effectively enriching neurogenic exosomes in blood

Examples

Experimental program
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Effect test

Embodiment 1

[0041] Example 1 An automated device for effectively enriching neurogenic exosomes in blood

[0042] An automated device for effectively enriching neurogenic exosomes in blood, which includes a reaction rack 1 at the bottom and a movable operating rack 2 above; and controls the operating rack 2 to run according to a predetermined track and the reaction rack 1 according to the setting The control structure 3 of the program reaction; the reaction rack 1 is provided with an oscillation incubation structure 11 required for exosome enrichment, a centrifugal structure 12, a reagent placement structure 13, a consumable placement structure 14, a discard placement structure 15, and a sample placement structure 16, sample information identification structure 17, enriched sample collection structure 18 after reaction; the operation rack 2 is provided with a tube body moving structure 21 to realize the movement of the tube body between different structures, to realize the liquid transfer f...

Embodiment 2

[0055] Example 2 An automated device for effectively enriching neurogenic exosomes in blood

[0056] An automated device for effectively enriching neurogenic exosomes in blood, which includes a reaction rack 1 at the bottom and a movable operating rack 2 above; and controls the operating rack 2 to run according to a predetermined track and the reaction rack 1 according to the setting A program reaction control structure 3; characterized in that, the reaction rack 1 is provided with an oscillation incubation structure 11 required for exosome enrichment, a centrifugal structure 12, a reagent placement structure 13, a consumable placement structure 14, and a discard placement structure 15 , a sample placement structure 16, a sample information identification structure 17, and a reaction enriched sample collection structure 18; the operating frame 2 is provided with a tube body moving structure 21 that can move the tube body between different structures, so as to realize the liquid...

Embodiment 3

[0072] Example 3 An automated device for effectively enriching neurogenic exosomes in blood

[0073] An automated device for effectively enriching neurogenic exosomes in blood, which includes a reaction rack 1 at the bottom and a movable operating rack 2 above; and controls the operating rack 2 to run according to a predetermined track and the reaction rack 1 according to the setting A program reaction control structure 3; characterized in that, the reaction rack 1 is provided with an oscillation incubation structure 11 required for exosome enrichment, a centrifugal structure 12, a reagent placement structure 13, a consumable placement structure 14, and a discard placement structure 15 , a sample placement structure 16, a sample information identification structure 17, and a reaction enriched sample collection structure 18; the operating frame 2 is provided with a tube body moving structure 21 that can move the tube body between different structures, so as to realize the liquid...

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Abstract

An automated device for effectively enriching neurogenic exosomes in blood, which includes a reaction rack at the bottom and a movable operating rack at the top; and controls for controlling the operation of the operating rack according to a predetermined track and the reaction of the reaction rack according to a set program Structure; the reaction rack is equipped with the vibration incubation structure, centrifugal structure, reagent placement structure, consumable placement structure, discard placement structure, sample placement structure, sample information identification structure, and enrichment after reaction required for exosome enrichment Sample collection structure; the operation rack is equipped with a tube body moving structure to move the tube body between different structures, and realizes a liquid-taking and liquid-feeding structure for liquid transfer in the whole process; The EP tube marking and identification structure when using the EP tube for the first time; through the control structure to control the operation frame to move and clamp the sample tube and various liquids, and automatically enrich the sample according to the set procedure, the whole process can effectively enrich the neurogenic exosomes.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to an automatic enrichment device for exosome enrichment; in particular, it relates to an automatic equipment for effectively enriching neurogenic exosomes in blood. Background technique [0002] Neurodegenerative diseases are caused by the loss of neurons and / or their myelin sheath, which worsens and becomes dysfunctional over time. Such as Alzheimer's disease (AD), Parkinson's disease (PD), and prion diseases. At present, the definite clinical diagnosis of neurodegenerative diseases relies on PET (positron emission computed tomography), and when pathological changes occur, the disease often develops to an irreversible and reversible stage. [0003] The detection of relevant biomarkers through cerebrospinal fluid can diagnose such diseases in advance, but the sampling method of cerebrospinal fluid is traumatic to the human body, and the patient's willingness is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/36C12M1/00
CPCC12M23/48C12M23/52C12M27/16C12M41/48C12M47/04
Inventor 马咏翔吴航董硕
Owner 北京凯祥弘康生物科技有限公司
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