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System and method for integrated sensor cartridge

A biosensor and biochip technology, applied in the field of biosensors, can solve the problems of complex, expensive and unreliable microfluidic design, and achieve the effects of improving flow field uniformity, reducing stress, and reliable device structure

Pending Publication Date: 2021-06-25
MGI TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many current microfluidic designs are complex and expensive to manufacture and use, and often unreliable

Method used

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  • System and method for integrated sensor cartridge
  • System and method for integrated sensor cartridge
  • System and method for integrated sensor cartridge

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0042] figure 1 is a simplified cross-sectional view illustrating a microfluidic device according to some embodiments of the invention. Such as figure 1 As shown, the microfluidic device 100 includes a substrate 110 , such as a PCB (printed circuit board), a biochip 120 covering the PCB 110 , and a microfluidic housing 130 covering the biochip 120 and the PCB 110 . The microfluidic housing 130 is attached to the biochip 120 using a first adhesive layer 141 to form a flow cell, and the microfluidic housing is attached to the PCB 110 using a second adhesive layer 142 to provide mechanical support. For example, the biochip 120 may be attached to the PCB 110 using the die attach adhesive layer 113 that attaches the biochip 120 to the PCB 110 . It should be understood that the substrates described herein are not limited to PCBs, and other substrates such as semiconductor (eg, silicon) substrates, glass substrates, ceramic substrates, etc. may also be used.

[0043] The biochip 1...

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Abstract

A microfluidic apparatus (100) can include a PCB (110), a biological chip (120) overlying the PCB (110), and a microfluidic housing (130) overlying the biological chip (120) and the PCB (110). The microfluidic apparatus (100) also has a first adhesive layer (141) attaching the microfluidic housing (130) to the biological chip (120) and a second adhesive layer (142) attaching the microfluidic housing (130) to the PCB (110). The second adhesive layer (142) is thicker than the first adhesive layer (141). The first adhesive layer (141) comprises a first adhesive material, and the second adhesive layer (142) comprises a second adhesive material.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 767,998, filed November 15, 2018, the entire contents of which are incorporated herein by reference. technical field [0003] The present invention relates generally to biosensors for biological or chemical analysis, and more particularly to the integration of microfluidic housings with biochips and substrates such as printed circuit boards (PCBs) to form integrated sensor cartridges or microfluidic housings. Method for Fluidic Devices. Background technique [0004] High-throughput analysis of chemical and / or biological substances is an important tool in the fields of diagnosis and therapy. Attached arrays of chemicals and / or biological substances can be designed to define specific target sequences, analyze gene expression patterns, identify specific allelic variants, determine copy number of DNA sequences, and identify proteins genome-wide...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00
CPCB01L2300/0627B01L3/502715B01L2300/0887B01L3/502707B01L2200/04B01L2200/0689B01L2300/0636B01L2300/0877B01L2200/0663C09J7/20C09J7/38C09J163/00C09J2203/326
Inventor 王亮诚·弗兰克·钟李世峰
Owner MGI TECH CO LTD