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Monatomic preparation capable of treating intestinal diseases of animals and preparation method of monatomic preparation

A technology for intestinal diseases and animal body, applied in the direction of antiviral agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as polluted environment, slow effect, yellow diarrhea, pullorum, etc.

Inactive Publication Date: 2021-07-06
LINKWAY TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the research conclusions on intestinal diseases of livestock and poultry mainly include three aspects: one is viral infection, such as common rotavirus infection, which causes pigs, chickens and other livestock and poultry to be depressed, unwilling to walk around, vomiting after eating, and often due to dehydration. And die within 3-7 days; The second is bacterial infection, such as common Escherichia coli infection, which causes large-scale occurrence of yellow scour, pullorum, edema, etc. in pigs, chickens and other livestock and poultry, and the fatality rate is relatively high; External factors such as mildew and feed mildew lead to a decline in the immunity of livestock and poultry. As a result, harmful bacteria and viruses take advantage of it, causing livestock and poultry to suffer from intestinal diseases
[0004] At present, there are many kinds of drugs on the market to treat intestinal diseases of livestock and poultry, which can be summarized into three categories: First, most feeding enterprises use mainstream injection or feeding antibiotics to treat bacterial intestinal diseases, which have the advantages of quick effect and good economic benefits The disadvantage is that it has little effect on viral infections, and antibiotics will cause large-scale drug resistance of bacteria, resulting in an increasing amount of antibiotics, polluting the environment, and endangering human health, and many antibiotics have been banned by my country; Various drugs improve the immunity of livestock and poultry. The advantage is that the disease rate of livestock and poultry is reduced, and the meat quality of livestock and poultry is improved. The disadvantage is that the effect is slow, and it is helpless in the face of acute intestinal diseases, and continuous feeding is required, and the cost is high; Nano-ZnO and other bactericidal disinfectants eliminate the bacteria and viruses that cause intestinal diseases from the root. human health

Method used

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  • Monatomic preparation capable of treating intestinal diseases of animals and preparation method of monatomic preparation
  • Monatomic preparation capable of treating intestinal diseases of animals and preparation method of monatomic preparation
  • Monatomic preparation capable of treating intestinal diseases of animals and preparation method of monatomic preparation

Examples

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preparation example 1

[0047] A method for preparing a single-atom medicament, comprising the following steps:

[0048] S1, preparing a porous silica carrier;

[0049] S1.1, use 300-325 mesh animal-specific food-grade montmorillonite as raw material, add hydrochloric acid solution of PH=6, wherein the mass ratio of montmorillonite to hydrochloric acid solution is 1:2, at a temperature of 50°C and a rotational speed Stir for 3 hours at 500rpm, wash and filter with distilled water until neutral;

[0050] S1.2, dry in a vacuum oven at 80°C, grind the obtained product into powder, add a sodium carbonate solution with pH=8, wherein the mass ratio of the powder to the sodium carbonate solution is 50:1, and mix evenly;

[0051] S1.3, transfer to the reactor for roasting and puffing. The roasting temperature of the reactor is 450°C, the pressure inside the kettle is 1.0MPa, and the roasting time is 10min. Take it out and cool it naturally. , the grinding ball is zirconia), and ground to a particle size of...

preparation example 2

[0058] S1, preparing a porous silica carrier;

[0059] S1.1, use 300-325 mesh animal-specific food-grade montmorillonite as raw material, add hydrochloric acid solution of PH=6, wherein the mass ratio of montmorillonite to hydrochloric acid solution is 1:2, at a temperature of 50°C and a rotational speed Stir for 3 hours at 500rpm, wash and filter with distilled water until neutral;

[0060] S1.2, dry in a vacuum oven at 80°C, grind the obtained product into powder, add a sodium carbonate solution with pH=8, wherein the mass ratio of the powder to the sodium carbonate solution is 50:1, and mix evenly;

[0061] S1.3, transfer to the reactor for roasting and puffing. The roasting temperature of the reactor is 450°C, the pressure inside the kettle is 1.0MPa, and the roasting time is 10min. Take it out and cool it naturally. , the grinding ball is zirconia), and ground to a particle size of 1 μm to prepare a porous carrier precursor;

[0062] S2, to prepare the active metal sing...

preparation example 3

[0068] A method for preparing a single-atom medicament, comprising the following steps:

[0069] S1, preparing a porous silica carrier;

[0070] S1.1, use 300-325 mesh animal-specific food-grade montmorillonite as raw material, add hydrochloric acid solution of PH=6, wherein the mass ratio of montmorillonite to hydrochloric acid solution is 1:2, at a temperature of 50°C and a rotational speed Stir for 3 hours at 500rpm, wash and filter with distilled water until neutral;

[0071] S1.2, dry in a vacuum oven at 80°C, grind the obtained product into powder, add a sodium carbonate solution with pH=8, wherein the mass ratio of the powder to the sodium carbonate solution is 50:1, and mix evenly;

[0072] S1.3, transfer to the reactor for roasting and puffing. The roasting temperature of the reactor is 450°C, the pressure inside the kettle is 1.0MPa, and the roasting time is 10min. Take it out and cool it naturally. , the grinding ball is zirconia), and ground to a particle size of...

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PUM

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Abstract

The invention relates to the technical field of veterinary drugs, in particular to a monatomic preparation capable of treating intestinal diseases of animals and a preparation method of the monatomic preparation. The monatomic preparation capable of treating intestinal diseases of animals comprises the following raw materials in percentages by mass: 45-55% of a monatomic medicament, 35% of ethanol, 1-4% of an emulsifier, 0-1% of a synergist and 7-18% of a coating agent. The monatomic preparation provided by the invention can be used for efficiently and rapidly treating various intestinal diseases of animals, is mixed into livestock and poultry drinking water according to the dosage of 4000 ppm, is fed to livestock and poultry suffering from intestinal diseases, and can take effect within 2-3 days; and drug dependence of livestock and poultry is avoided, and environmental pollution is also avoided. Under coating protection, decomposition loss of the monatomic preparation provided by the invention by gastric juice of animals is avoided, the monatomic preparation smoothly reaches intestinal tracts, and under the action of intestinal juice, the monatomic preparation capable of treating intestinal diseases of animals is exposed and takes effect in intestinal tracts, so that bacteria and viruses causing intestinal diseases are fundamentally solved.

Description

technical field [0001] The application relates to the technical field of veterinary medicine, in particular to a single-atom preparation capable of efficiently treating porcine epidemic diarrhea caused by porcine epidemic diarrhea virus PEDV and a preparation method thereof. Background technique [0002] With the continuous improvement of the scale and intensification of my country's livestock and poultry breeding industry, various breeding problems appear in the breeding process, the most prominent breeding problem is that livestock and poultry are prone to large-scale intestinal diseases. Intestinal diseases lead to symptoms such as acute diarrhea, listlessness, loss of appetite, cessation of rumination, and weight loss in livestock and poultry. In severe cases, it can lead to the death of large-scale livestock and poultry, bringing immeasurable economic losses. [0003] At present, the research conclusions on intestinal diseases of livestock and poultry mainly include thr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/34A61K33/30A61K33/26A61K9/50A61K47/02A61K47/08A61K47/14A61K47/32A61K47/26A61P1/00A61P31/04A61P31/12A61P31/14
CPCA61K33/34A61K33/30A61K33/26A61K9/5026A61K9/5015A61K9/501A61K47/02A61K47/08A61K47/14A61P1/00A61P31/04A61P31/12A61P31/14A61K2300/00
Inventor 赵超王晶黄红锋吴宇波
Owner LINKWAY TECH CO LTD
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