Yin-nourishing traditional Chinese medicine composition containing licorice and dandelion and application thereof

Abstract

The invention provides a composition containing licorice and other medicinal and food homologous Chinese medicinal ingredients (named Gancao Yangyin Decoction) and its application in rheumatoid arthritis and ovarian cancer. In parts by weight, the traditional Chinese medicine composition of Gancao Yangyin Decoction includes the following components: 2 to 6 parts of licorice, 1 to 5 parts of ginseng, 1 to 3 parts of dried ginger, 1 to 3 parts of dandelion, 2 to 6 parts of Luo Han Guo, jade 1 to 5 parts of bamboo, 2 to 6 parts of jujube. The traditional Chinese medicine composition provided by the invention adopts licorice as the monarch drug, ginseng and Polygonatum odoratum as the minister drug, dandelion, dried ginger and Luo Han Guo as the adjuvant drug, and jujube as the envoy drug. Moisturizes the lungs and relieves coughs, promotes body fluids and quenches thirst, nourishes yin and supports yang, and regulates the heart, lung, spleen and large intestine meridians. In vitro studies have confirmed that the drug serum of this formula inhibits the proliferative activity of rheumatoid arthritis synovial fibroblasts and ovarian cancer cells, and promotes their apoptosis. It has potential development value in the treatment of rheumatoid arthritis and ovarian cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for nourishing yin containing licorice and dandelion and an application thereof. Background technique [0002] Rheumatoid arthritis (rheumatoid arthritis, RA) is one of the most common rheumatic diseases in rheumatic diseases, and the prevalence is as high as 0.5-1.0% of the population (MCINNES I B, SCHETT G. Pathogenetic insights from the treatment of rheumatoid arthritis[J]. Lancet. 2017, 389(10086): 2328-2337.). Rheumatoid arthritis is a serious hazard, and its prominent pathological feature is synovial hyperplasia and erosion of articular cartilage and bone, eventually leading to joint destruction and deformity. The clinical manifestations are joint pain, deformation and loss of function, and even involve multiple systems and organs of the human body, concurrent with interstitial lung di...

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Problems solved by technology

The lack of strict randomized clinical trials and convincing basic research hinders the application and promotion of traditional Chinese medicine

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