PWTT-based dynamic continuous blood pressure measurement method

A blood pressure measurement and dynamic technology, used in vascular assessment, cardiac catheterization, etc., can solve the problem of inability to adjust flexibly and dynamically, and achieve the effect of shortening measurement time, reducing the number of calibrations, and reducing storage space

Active Publication Date: 2021-07-27
上海立阖泰医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The purpose of the present invention is to overcome the defect that the existing algorithm cannot be flexibly and dynamically adjusted in terms of calculation time and calculation error, and provides a dynamic continuous blood pressure measurement method based on PWTT, wherein the PWTT data is flexibly screened, and through PWTT, arm length The PWV is obtained from the average distance from the shoulder to the heart of a normal person, which makes the final calculated PWV more accurate. At the same time, when calculating blood pressure based on PWTT, not only the direct correlation between the two is considered, but also high pressure (SBP), pulse pressure (PP), The relationship between heart rate (PULSE) and blood pressure, by calculating the autocorrelation coefficient, regression coefficient and regression constant between each group of data, and finally calculate the blood pressure value according to the calculated parameter regression equation, the result is more accurate, in addition, in the process The real-time collected data and calibration data will also participate in data screening and subsequent calculation of regression coefficients, etc., and the real-time collected data will be added to the calibration area for new measurements. By continuously optimizing the calibration area, the blood pressure measurement results will be more accurate.

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0301] The comparison of the blood pressure measured when the heart rate regression coefficient is not added in the calculation of blood pressure in the traditional method and the blood pressure in the scheme of adding the heart rate regression coefficient in the present invention is given below.

[0302] 1. Comparison of blood pressure measured without heart rate regression coefficient and standard sphygmomanometer

[0303] Table 2 Blood pressure values ​​of systolic blood pressure SBP and diastolic blood pressure DBP measured by the calibrated sphygmomanometer at different stages (calibration / measurement) and different states (rest / exercise) of the test subject

[0304]

[0305]

[0306] Table 3 The m value and p value in the unadded heart rate calculation formula adopted in the PWTT blood pressure measurement watch

[0307] SBP PP p 0.590067424 0.233961592 m 121.4982 57.8830

[0308] The blood pressure calculation formula without heart r...

Embodiment 2

[0340] According to a specific embodiment of the present invention, the continuous blood pressure measurement method is compared with the dynamic continuous blood pressure measurement method.

[0341] 1. Comparison of continuous blood pressure measurement method and standard sphygmomanometer

[0342] Table 9 The blood pressure values ​​of systolic blood pressure SBP and diastolic blood pressure DBP, pulse pressure PP value, PWV value and heart rate PULSE value measured by the tester on different consecutive days and at the same time by calibrating the sphygmomanometer

[0343]

[0344] Table 10 The m value, p value and q value in the calculation formula of the continuous blood pressure measurement method

[0345] SBP PP p 4.572888 6.833748 q 0.439205 0.287324 m 80.29063 6.01259

[0346] In the above table:

[0347] p is the regression coefficient of SBP or PP and PWV;

[0348] q is the regression coefficient of SBP or PP and heart rate...

Embodiment 3

[0385] According to a specific embodiment of the present invention, the following table is the same tester, fixed arm length, N, M and a parameters, respectively calculate the PWTT value of different numbers before discarding, the influence on the value of the final PWV.

[0386] Among them, real PWV=3.566243, arm length L=630mm, N=15, M=10%, a=200mm.

[0387] Table 12 The impact of discarding different numbers of PWTT values ​​on PWV during primary screening

[0388]

[0389] The real PWV value is measured by a brand AECG100 ECG / PPG and PWTT multifunctional physiological signal tester. According to the second column of the above table, it can be obtained Figure 10 . according to Figure 10 It can be seen that the PWTT data fluctuations of the first 5 collection points are relatively large, and the data tends to be stable after 5 collection points. Therefore, when P=5-9, that is, when the first 5 to 9 PWTT values ​​are discarded, the PWV calculation The result is closer...

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Abstract

The invention provides a PWTT-based dynamic continuous blood pressure measurement method, and belongs to the technical field of non-invasive continuous blood pressure measurement. The PWTT data are flexibly screened, the PWV is obtained through the PWTT, the arm length and the average distance from the shoulder to the heart of the normal person, the precision of the finally calculated PWV is higher, meanwhile, when the blood pressure is calculated based on the PWTT, the direct correlation of the two is considered, the relation between high pressure, pulse pressure, the heart rate and the blood pressure is also considered, By calculating the autocorrelation coefficient, the regression coefficient and the regression constant among each group of data and finally calculating the blood pressure value according to the calculated parameter regression equation, the result is more accurate, in addition, in the process, data collected in real time and calibration data participate in data screening and subsequent calculation of the regression coefficient and the like together, and the real-time acquired data is added into a calibration area for new measurement, and the calibration area is continuously optimized, so that the blood pressure measurement result is more accurate.

Description

technical field [0001] The invention relates to the technical field of non-invasive continuous blood pressure measurement, in particular to a dynamic continuous blood pressure measurement method based on PWTT. Background technique [0002] Pulse Wave Transit Time (PWTT) is the transmission time of the arterial blood pressure wave along the vessel wall. This time is composed of the time from the start of the heart contraction to the opening of the aortic valve to the pulsation of blood in the aorta, which is transmitted to the peripheral part through the blood vessel. , PWTT parameters can be obtained from the ECG and pulse wave of the wrist. At present, there are a large number of clinical trials showing that the relationship between pulse wave transit time and blood pressure is a clear phenomenon in physiology. Using this phenomenon, combined with individual gender, height, Based on basic characteristics such as body weight, arm length, and age, a special algorithm can be u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/021
CPCA61B5/02125
Inventor 李龙
Owner 上海立阖泰医疗科技有限公司
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