A Simplified Calculation Method and Plaque Rupture Risk Quantification Evaluation System Based on Coronary Multimodal Image Crack Formation and Extension

A technology that simplifies calculation and risk factor, which is applied in the medical field and can solve the problem that it is not suitable for coronary plaque risk assessment.

Active Publication Date: 2022-01-18
THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the variability of coronary artery morphology over time during the cardiac cycle, this method is not well suited for the risk assessment of coronary plaques.
[0005] In conclusion, although the above-mentioned system software and patent documents obtain plaque stability assessment methods from different image sources and corresponding calculation methods, a single image source cannot fully present the tearing cracks in the superficial wall of lesioned coronary plaques penetrating the fibrous cap. plaque rupture process

Method used

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  • A Simplified Calculation Method and Plaque Rupture Risk Quantification Evaluation System Based on Coronary Multimodal Image Crack Formation and Extension
  • A Simplified Calculation Method and Plaque Rupture Risk Quantification Evaluation System Based on Coronary Multimodal Image Crack Formation and Extension
  • A Simplified Calculation Method and Plaque Rupture Risk Quantification Evaluation System Based on Coronary Multimodal Image Crack Formation and Extension

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Embodiment 1

[0037] The present invention provides a simplified calculation method for the risk quantification index of crack formation and expansion in the process of individualized plaque rupture of patients based on coronary multimodal images. The following uses a specific example to use coronary angiography and optical coherence tomography as coronary artery angiography and optical coherence tomography respectively. The source of the multi-mode image is described in detail for the calculation method of the present invention. Those skilled in the art should understand that in this embodiment, the coronary artery image of a diseased vessel with a specific degree of stenosis and the OCT image data of a specific plaque component are used as an example, and this specific coronary artery disease and plaque type should not be used as an example. Or the corresponding image modality is understood as limiting the protection scope of the present invention.

[0038] In a specific embodiment of the...

Embodiment 2

[0074] In this specific embodiment, the present invention also provides a simplified calculation method based on coronary multimodal image crack formation and propagation and an evaluation system for plaque rupture risk quantification (such as figure 1 shown), the system includes:

[0075] The image input module is mainly used for the input of coronary multimodal images, including coronary angiography and coronary intraluminal images (optical coherence tomography, intravascular ultrasound imaging, etc.);

[0076] The image processing module is mainly used for key frame image screening, image enhancement, contour segmentation, plaque component identification, grid generation, and spatial position correspondence between multi-mode images of vessels of interest;

[0077] The quantification module of coronary plaque is mainly used for the description of anatomical indicators, including the diameter stenosis rate based on angiography, the minimum lumen diameter area, etc.; and the ...

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Abstract

The invention discloses a simplified calculation method based on the formation and expansion of coronary multi-mode image cracks and an evaluation system for quantifying the risk of plaque rupture, which acquires coronary angiography images and intracavity images (such as optical coherence tomography) through an image input module Using image processing technology to segment and register interested blood vessels or plaques on different images, and quantitatively obtain the anatomical indexes of diseased coronary plaques, and further calculate superficial plaques based on time-series coronary angiography The distribution of wall dynamics indices and the determination of relatively high-risk locations along the longitudinal direction of the vessel to obtain the fatigue risk factor for localized crack formation in the superficial wall. The present invention combines the anatomical indicators of coronary multimodal images, and further increases the quantitative assessment of the risk of plaque crack expansion based on superficial coronary crack formation and cross-sectional images, so as to evaluate plaque more completely and comprehensively. rupture process.

Description

technical field [0001] The invention relates to a simplified calculation method and system for plaque rupture risk based on coronary images, and belongs to the field of medical technology. Background technique [0002] Plaque rupture secondary to occlusive thrombosis is the main pathogenesis of acute coronary syndrome. Quantitative assessment of the risk of plaque rupture will help clinicians formulate individualized prevention and treatment strategies to improve the long-term prognosis of patients with coronary heart disease. At present, the evaluation methods for identifying vulnerable plaques are mainly divided into two categories, namely, the evaluation of anatomical quantification indicators based on imaging, and the functional evaluation based on imaging. The first category of evaluation methods includes the SNYTAX score of quantifying coronary anatomy by angiography, and the diagnosis of thin-cap fibroma vulnerable plaque based on intraluminal imaging, etc., but the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06T7/11G06T7/136G06T7/33G06T7/62G16H50/30A61B5/00
CPCG06T7/0012G06T7/11G06T7/136G06T7/62G06T7/33G16H50/30A61B5/7275G06T2207/10101G06T2207/30101G06T2207/10028G06T2207/20081
Inventor 吴信雷卢孔场陈徐亮褚茂平
Owner THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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