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Compositions for treatment of symphysiolysis

A technology of pubic symphysis and composition, which is applied in the direction of drug combination, active ingredient of heterocyclic compounds, drug delivery, etc., and can solve problems such as limited safety information

Pending Publication Date: 2021-09-07
吉尔蓬普
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Opioids available for postpartum women, but safety information on effects of long-term opioid use during pregnancy is limited

Method used

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  • Compositions for treatment of symphysiolysis
  • Compositions for treatment of symphysiolysis
  • Compositions for treatment of symphysiolysis

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0069] A 30-year-old female patient with a weight of about 60 kilograms has never been injured in the left leg of the car accident, triggered complex local pain syndrome. Walking ability is damaged and need canes to act. During pregnancy, she was diagnosed with pubic joint loose solve, because she could only sit in a wheelchair. The treatment methods including analgesic, NSAID, bed rest and external pelvic fixation have tried, but there is no success.

[0070] 1% hydrochloride was injected under subcutaneous hydrochloride in the groin area, and the amount was diluted with 5 ml of physiological saline, injected into each side of the groin area. After administration, the patient can stand, no pain, no longer need to take a wheelchair. Treatment lasts for an hour. After an hour, the additional 0.5% hydrochloride ratio was administered at each side of the groin area, and the amount was 5 ml, diluted with a 5 mL saline solution. The patient's activity time is extended for nine hours.

...

example 2

[0073] A 31-year-old woman with a weight of about 80 kilograms. At 33r weeks of pregnancy, doctors have diagnosed her confined symptoms by detecting significant sensitivity to the pubic joint joints. She is overall and healthy and does not take drugs regularly. She didn't have any surgery before. She has 3 birth. Her first birth at week 39th, the fetus weight was 3750 grams. Her second birth is 3950 grams of fetal weight. Her third childbirth was 4100 grams of fetal weight. She is not a diabetic patient. It is recommended that she has orthopedic support, physical therapy, and oral articular interest, and An Nai near drug treatment to control pain. It is recommended to stay in bed.

[0074] At 35 weeks, she felt an increase in the severity of the pubic symptoms. The orthopedic support method she used is not sufficient to relieve symptoms. She has considers the induction of labor and using a boot to improve their actions.

[0075] She accepted 5 ml (mL) 1% hydrochloride Liacaine, af...

example 3

[0079] A 31-year-old woman with a weight weight of about 60 kilograms, and his 20th week of the main vocal pain, spreading to her right leg. She is difficult to walk, seem to drag the right leg. After examination, there is no obvious sensitivity of the pubic joint joint joint. The sensitivity of the right ankle joint is obvious. Doctors recommends reducing physical activity.

[0080] After about six weeks, the patient has a significant sensitivity when the patient is reviewed, and the right is a certain sensitivity. It is recommended to use angesic and hip orthopedic fixation. Use NSAID until 31st. The patient had a published symptoms in the 29th week, and the symptoms were relieved using NSAID (sodium diclofenac).

[0081] At 31 weeks, the patient feels the pubic combination loose solicity. She doesn't need to use a boot. Due to the posterior groin and back pain, there is a temporary paralysis, sleep difficulties and sitting difficulties when walking. It is recommended to subcuta...

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Abstract

Described herein are compositions comprising an effective amount of a local anesthetic agent for blocking neural transmission at the superficial inguinal ring or canal, for treatment of symphysiolysis. The compositions may be for administration through the subcutaneous or transdermal route, preferably to a region between the symphysis pubis and the anterior superior iliac spine. Methods for treatment of symphysiolysis are also described.

Description

[0001] Cross-reference [0002] The claims of the disclosure of which are incorporated by reference in its entirety in its entirety in its entirety in its entirety in its entirety. Technical field [0003] This article provides compositions and methods for the treatment of pubic symphosaine. Background technique [0004] Low back pain, also known as the pubic joint loose solicity, is a common condition caused by pelvic joint dislocation during pregnancy and childbirth. It is associated with the unstable pelvis, which is related to the increase in joint activities. The pubic combined loose disorder may involve the combination of the front pelvic joint (pubic joint), the postpone joint (left and right iliac art) or the combination of both. The pubic combined loose disorder can cause a range of symptoms, including stress or pain, knee or back and other parts of the pelvic region and / or lower abdomen, or the functional loss of leg activity and functional paralysis. In some cases, th...

Claims

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Application Information

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IPC IPC(8): A61K31/165A61K31/167A61K31/135A61K31/445A61K9/00A61P19/00A61P23/02
CPCA61K31/167A61K31/445A61P19/00A61P23/02A61K9/0019A61K9/7023A61K31/137A61K45/06A61K31/451
Inventor 吉尔·蓬普
Owner 吉尔蓬普
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