The invention relates to the technical field of experimental
medicine, and discloses a controllable hierarchical thoracic and abdominal knocking injury
animal model establishment method, which comprises the following steps: S1, selecting a healthy beagle; s2, trachea cannula
vein general
anesthesia is conducted, a
medicine injection cannula is connected with a
breathing machine, and suction of 1% of
isoflurane is maintained; s3,
lying on the back and fixing on an experiment table with a thoracico-abdominal
exposure hole; s4, a DZHE-01 injury platform is used for being aligned with the chest and the
abdomen; s5, regulating pressure, grading and causing injury, and recording an
overpressure curve; s6, recording indexes according to time after injury, and performing detection and
image inspection. According to the method for establishing the controllable graded chest and
abdomen knocking injury
animal model, a healthy adult beagle is supine and fixed to an experiment table with chest and
abdomen exposure holes, the upper edge of the sternum is exposed to symphysis pubis, a 5 mm
nitrile rubber pad is laid on the table top, a
lead plate is used for shielding the
head and neck, rubber protection plates are used for shielding the limbs, and DZHE-01 platform shock
waves only act on the chest and the abdomen; by combining light single-time, middle 1-2-time and heavy two-time grading injury, multiple thoracic and abdominal organ injuries are simulated, and the problem that an existing model is single in part is solved.