Compound amoxicillin breast injectant and preparation method thereof
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A breast injection and amoxicillin technology, which is applied in the formulation and preparation field of compound amoxicillin breast injection, can solve the problems of slow action, low development value, insignificant curative effect and the like
Inactive Publication Date: 2021-09-10
JILIN UNIV
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Problems solved by technology
The compound traditional Chinese medicine ingredients in the existing patented technology treat dairy cow mastitis, the effect is slow, and the curative effect is not significant
The dosage is too large, and the value of product development is low
Method used
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Embodiment 1
[0024] (1) The prescription of 100g compound amoxicillin breast injection is as follows:
[0025] Amoxicillin 6.6g
[0026] Ligustrum extract 2g
[0027] Hydrogenated Castor Oil 1g
[0028] Glyceryl monostearate 1g
[0029] Vitamin E 0.1g
[0030] Add soybean oil for injection to 100g
[0031] (2) 70% of the prescription amount of soybean oil for injection is filtered, and the processed soybean oil is heated to 80° C. for later use.
[0032] (3) Add the suspending agent hydrogenated castor oil and the surfactant glyceryl monostearate into the above-mentioned soybean oil for injection until completely dissolved.
[0033] (4) Continue cooling the mixed solution to about 30°C, and add vitamin E to the obtained mixed solution during rapid stirring until the antioxidant dissolves; set aside;
[0034] (5) Add the prescribed amount of amoxicillin and Ligustrum lucidum extract, and then add filtered soybean oil to 100g.
[0035] (6) Process the prepared above solution with a hi...
Embodiment 2
[0037] The prescription of compound amoxicillin breast injection per 100g is as follows:
[0038] Amoxicillin 6.6g
[0039] Ligustrum extract 3g
[0040] Hydrogenated Castor Oil 1g
[0041] Glyceryl monostearate 1g
[0042] Vitamin E 0.1g
[0043] Add soybean oil for injection to 100g
[0044] Others are the same as embodiment one
Embodiment 3
[0046] The prescription of compound amoxicillin breast injection per 100g is as follows:
[0047] Amoxicillin 6.6g
[0048] Ligustrum extract 4g
[0049] Hydrogenated Castor Oil 1g
[0050] Glyceryl monostearate 1g
[0051] Vitamin E 0.1g
[0052] Add soybean oil for injection to 100g
[0053] Others are the same as embodiment one
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Abstract
The invention relates to a veterinary compound amoxicillin breast injectant. The main drugs of the veterinary compound amoxicillin breast injectant comprise amoxicillin and a fructus ligustri lucidi extract, after a wetting agent and a suspending aid are added and dispersed, the veterinary compound amoxicillin breast injectant can be easily mixed uniformly, drug components are stably and uniformly dispersed in soybean oil, and a sustained release effect is remarkable. The veterinary compound amoxicillin breast injectant is used for treating mastitis of cows in the lactation period and has the advantages that the traditional Chinese medicine and Western medicine compound components increase a bactericidal effect, can enhance the bactericidal effect of the amoxicillin and improves a clinical treatment effect.
Description
technical field [0001] The invention belongs to the field of veterinary drug preparations, in particular to a composition of compound amoxicillin breast injection and a preparation method thereof Background technique [0002] Cow mastitis has become one of the most difficult diseases in the dairy industry to cure completely. According to reports, the economic loss caused by cow mastitis in the world is as high as 35 billion U.S. dollars every year. Where there are dairy herds, there will be cow mastitis. Most developed countries have suffered heavy economic losses due to cow mastitis, among which the loss due to reduced milk production accounts for about 70%, and 14% of cows are eliminated in advance due to illness, and the milk is discarded due to bacteria and other pathogenic bacteria. Milk accounts for 7%, which has seriously affected the breeding and development of animal husbandry. Among these influencing factors, pathogenic microorganisms are an important factor lead...
Claims
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Application Information
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