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Composition for relieving gout and preparation method and application thereof

A composition and technology for gout, applied in the directions of application, drug combination, medical preparations containing active ingredients, etc., can solve problems such as side effects of the human body, and achieve the effect of high degree of industrialization, no irritation, and local pain relief

Pending Publication Date: 2021-09-17
JILIN WEIYIKANG BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the gout-improving products on the market contain different levels of chemical drug ingredients, which have more or less corresponding side effects on the human body

Method used

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  • Composition for relieving gout and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040]A composition for relieving gout, prepared by the following method:

[0041] (1) Material selection

[0042] Select materials according to the following parts by weight:

[0043] Take 35 parts of amaranth, 7 parts of corn silk, 25 parts of cherry concentrate, 7 parts of Jerusalem artichoke powder, 4 parts of mountain celery, 1.5 parts of vitamin C, 12 parts of erythritol, 1.5 parts of chlorella extract, 0.35 parts of zinc sulfate parts, 0.4 parts of potassium chloride, and 0.03 parts of vitamin B6.

[0044] Among them, the cherry concentrate is prepared by the following method: select high-quality fresh cherries with a complete appearance, wash and remove impurities, crush and extract juice through pressing equipment, and then undergo clarification and centrifugation to remove crude fibers in the peel and pulp to obtain pure cherries. The cherry juice is concentrated to one-tenth by a high-efficiency concentrator to obtain concentrated cherry juice.

[0045] Jerusalem...

experiment example

[0070] Get the product that above-mentioned embodiment and comparative example prepare, carry out mouse blood uric acid data index comparative experiment, determine its validity, specific method is as follows:

[0071] 1. Take Kunming male rats, weighing (25±5) g, and randomly divide them into blank group (administered with normal saline) and modeling group.

[0072] 2. The mice in the blank group were given intragastric administration of an equal volume of normal saline every day for feeding.

[0073] 3. The modeling group is given 20g·kg per day -1 Yeast extract was administered to the stomach to prepare a hyperuricemia model.

[0074] During the experiment, the body weight was weighed every morning. The modeling group gave the mice a large amount of purine substances by intragastric administration of yeast cream, which increased the blood urea level of the mice and disturbed the purine metabolism, thereby achieving the goal of high uric acid levels in the mice in a short ...

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Abstract

The invention relates to a composition for relieving gout and a preparation method and application thereof, and belongs to the technical field of pharmaceutical compositions. The composition for relieving gout is prepared from the following raw materials in parts by weight: 30-40 parts of edible amaranth, 5-10 parts of corn stigma, 20-30 parts of a cherry concentrated solution, 5-10 parts of jerusalem artichoke powder and 3-5 parts of celery. The composition for relieving gout has the effects of reducing generation of uric acid, accelerating decomposition and excretion of purine and relieving local pain. Medicinal and edible pure natural food materials are used as raw materials, and no essence, pigment, sweetening agent or preservative is added; the composition for relieving gout is natural, safe, efficient, free of toxic and side effects, free of irritation and free of addiction; and no pollution, no waste residue, no waste steam and no harmful substance are generated in the production process, and green production is achieved.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical compositions, in particular to a composition for relieving gout and its preparation method and application. Background technique [0002] Gout is a heterogeneous group of diseases caused by chronic disorders of purine metabolism. Clinical features are hyperuricemia, recurrent acute gouty arthritis, tophi, and interstitial nephritis, and in severe cases, joint deformities and dysfunction. Acute gouty arthritis is the most common first symptom in patients with gout. Acute gouty arthritis is caused by the abnormal uric acid excretion disorder in the patient's body and the deposition of monosodium urate in the synovium, cartilage and other tissues. It is a series of inflammatory symptoms, which is an acute onset of inflammation. Patients often wake up in the morning or late at night with severe pain. The reaction is redness, heat, and obvious tenderness in local joints within a few hours, acco...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P19/06A23L33/105A61K31/375A61K33/30A61K33/14A61K31/4415
CPCA61K36/21A61K36/899A61K36/736A61K36/28A61K36/23A61K31/375A61K36/05A61K33/30A61K33/14A61K31/4415A61P19/06A23L33/105A61K2236/31A61K2236/331A61K2236/53A61K2236/51A61K2236/55A61K2236/19A61K2236/39A23V2002/00A61K2300/00A23V2200/30A23V2250/21A23V2250/6402A23V2250/708A23V2250/7052A23V2300/14
Inventor 马亮安丽萍王曼丽
Owner JILIN WEIYIKANG BIOLOGICAL SCI & TECH
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