50 results about "Purine metabolism" patented technology

The invention relates to a formulated foodstuff with special medical purposes for patients with hyperuricemia and gout and provides a granule or powder solid beverage formed by mixing both medicinal and edible plants and extract thereof and a nutrient supplement. The granule or powder solid beverage contains submicron powder of green papaya, banana peel extract, green tea extract, sweet potato vine extract, kudzu vine root extract, Poria cocos extract, lotus leaf extract, cape jasmine extract, haw extract, licorice extract, stevia rebaudiana extract, xylo oligosaccharide, dipotassium hydrogen phosphate, sodium bicarbonate, vitamin C and nicotinamide. The granule or powder solid beverage provided by the invention is mainly directed at the characteristic of purine metabolism disorders of patients with hyperuricemia and gout, improves the complex process of biochemical metabolism like protein metabolism, purine metabolism and lipid metabolism in the bodies of patients with hyperuricemia and gout in virtue of special physiological active substances and targeted micronutrients included in the granule or powder solid beverage, indirectly inhibits synthesis of uric acid, promotes acid discharging and maintains nutrition functions like acid-base balance of the body.

The invention discloses a traditional Chinese medicine composition for treating gout. The traditional Chinese medicine composition comprises the following active pharmaceutical ingredients in parts by weight: 25-40 parts of rhizoma smilacis glabrae, 8-12 parts of peach kernel, 8-12 parts of radix paeoniae rubra, 8-12 parts of clematis root, 8-12 parts of angelica, 8-12 parts of Szechuan lovage rhizome, 8-12 parts of carthamus tinctorius, 10-20 parts of rhizoma dioscoreae hypoglaueae, 10-20 parts of zaocys dhumnade, 10-20 parts of piper wallichii, 1-6 parts of centipedes, 1-8 parts of scorpions and 8-12 parts of lumbricus. A preparation method of the traditional Chinese medicine composition comprises the following steps: directly crushing the active pharmaceutical ingredients subjected to conventional treatment into fine powder; screening the fine powder with 100 meshes; after uniform mixing, preparing capsules of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the advantages that rhizoma smilacis glabrae and rhizoma dioscoreae hypoglaueae are utilized for detoxication and dehumidification, and easing of joint movement; peach kernel, carthamus tinctorius, angelica, radix paeoniae rubra, Szechuan lovage rhizome and lumbricus are utilized for activating blood circulation to dissipate blood stasis, and activating meridians to stop pain; clematis root, piper wallichii, zaocys dhumnade, centipedes and scorpions are utilized for expelling wind-damp, activating the meridians, and stopping arthralgia; through the combination of such active pharmaceutical ingredients, swelling and hot pain of a joint can be remarkably relieved, and the functional movement of the joint can be improved; moreover, purine metabolism balance in a human body can be adjusted, the contents of blood uric acid and C-reactive protein can be lowered, and the effects of activating blood circulation to dissipate blood stasis, and relieving swelling and stopping pain can be realized.

The invention relates to the field of health care products, particularly to a traditional Chinese medicine composition, a preparation method thereof and a prepared health care wine. The traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 5-15 parts of bilberry, 5-15 parts of sambucus chinensis, 5-15 parts of rhodiola rosea, 5-15 parts of glossy ganoderma, and 10-20 parts of grape seed. The traditional Chinese medicine composition provided by the invention is prepared from the raw materials in a specific ratio, the prepared traditional Chinese medicine composition is high in effective active components, and can well repair the metabolizing function of a human body, so that the human body can normally function well, the traditional Chinese medicine composition has good repairing function for the purine metabolic disturbance of the human body, and has remarkable treatment effects on gout and rheumatic type diseases caused by purine metabolic disturbance; in addition, the traditional Chinese medicine composition has the efficacy of improving the immunity of the human body. The traditional Chinese medicine composition performs water extraction on the raw materials in a heating and distillating manner, the effective active components are effectively merged at a high temperature, and the traditional Chinese medicine composition has a better effect.

The invention provides application of a purine metabolism marker in preparation of a reagent for screening and diagnosing acquired drug resistance of a lung cancer molecular targeted drug. The purine metabolism marker is one or more of adenosine monophosphate, guanosine monophosphate, inosine monophosphate, xanthosine monophosphate, adenosine, guanosine, inosine, xanthosine, adenine, guanine, hypoxanthine, xanthine and uric acid. The metabolic marker has good diagnostic potential for acquired drug resistance of the lung cancer molecular targeted drug, can be used for diagnosis and curative effect monitoring of acquired drug resistance of the lung cancer molecular targeted drug, and has good guiding significance for development of subsequent clinical application research.

The invention relates to a Chinese medicine, in particular to a medicine for treating gout. The medicine can relieve toxic and side effects of reduced medicinal effects or serious adverse reactions generated by taking western medicines for a long time, is prepared from the following raw materials in part by weight: 10 to 36 parts of ampelopsis grossede, 20 to 50 parts of aspidopterys glabriuscula, 20 to 35 parts of giant knotweed rhizome and 10 to 30 parts of clerodendranthus spicatus, and is boiled in water and taken before dinner. The medicine for treating the gout has unique curative effects, is low in cost, addresses both the symptoms and root causes, does not have any side effect, improves purine metabolic disturbance fundamentally, and regulates the immune function of organisms comprehensively.

The present invention provides a system and method of maintaining and / or increasing cell viability by downregulating cellular metabolic rate under hypoxic conditions, wherein the availability of adenosine or derivatives thereof in the cell is increased and / or prolonged. The present invention also relates to a system and method of prolonging the survival of implanted cells that are under hypoxic condition until host neovascularization is achieved, wherein the availability of adenosine or derivatives thereof in the cell is increased and / or prolonged. The present invention also provides a system and method of maintaining and / or increasing cell viability by downregulating cellular metabolic rate under hypoxic conditions, wherein at least one purine metabolism enzyme inhibitor is applied to the cell.