Solid product of compound chicory root for adjusting disturbance of purine metabolism and preparation method of solid product

Abstract

The invention provides a solid product of compound chicory root for adjusting disturbance of purine metabolism and a preparation method of the solid product. The product can be applied to disturbanceof purine metabolism of hyperuricemia groups and preventing hyperuricemia complication. The solid product adopts natural edible Chinese herbal plants: chicory root, fructus gardeniae and rhizoma alpiniae officinarum, the main agent is extracted through refining extraction, and then scientifically matched with sodium citrate, thus the solid product is prepared, does not contain any artificial synthetic substances, and is all natural. The solid product can enhance purine metabolism of a human body, adjusts engine body and visceral organs, is beneficial for relieving pain and red heat symptoms ofa patient, gradually adjusts the operational situation of body organs, and adjusts damaged internal secretion of organisms. The technology is simple, the cost is low, the effective part can be easy to obtain, the preparation method is suitable for industrialized production, and the solid product can be used for preparing food, drugs and health care products for improving disturbance of purine metabolism of the hyperuricemia groups and preventing hyperuricemia complication.

Description

technical field [0001] The invention relates to the technical field of food health care, in particular to a solid product of compound chicory root for regulating purine metabolism disorder and a preparation method thereof. Background technique [0002] In recent years, with the improvement of social living standards, people's dietary structure is also undergoing tremendous changes. People's intake of high-sugar, high-protein, and high-purine foods is increasing day by day, causing the body to absorb nutrients while also making the body's organs perform high-load operations. Therefore, the incidence of various metabolic diseases shows an increasing trend year by year. [0003] Hyperuricemia (Hyperuricemia, HUA) is a group of hereditary and (or) acquired uric acid excretion reduction and (or) purine metabolism disorders in the body, resulting in increased blood uric acid [C.Remedios, M.Shah , A.G. Bhasker, et al. Hyperuricemia: a Reality in the Indian Obese [J]. OBES SURG, 2...

AI Technical Summary

Problems solved by technology

[0008] ① To reduce uric acid, the blood UA level should be maintained below the saturation point of uric acid crystals (6 mg / dL or 360 μmol / L). Allopurinol is a drug that can effectively inhibit the production of uric acid, and should start with a small dose (100 mg / d); but it is allergic Dermatitis, liver function damage, acute liver cell necrosis, upper gastrointestinal bleeding, bone marrow suppression and other adverse reactions, the treatment of asymptomatic hyperuricemia is not recommended

[0011] ④ Febuxostat (Feluxostat) [Becker MA, Schumacher HR, Wortmann RL, et al. Febuxostat compared with allopurinol in patients with hyperuricemia andgout [J]. N Engl J Med, 2005, 353(23): 2450-2461.] It is a new xanthine oxidase inhibitor that has been used in Europe and the United States, but its company claims that the drug is not recommended for asymptomatic hyperuricemia

[0012] ⑤ Hyperuricemia complicated with hypertension, coronary heart disease, diabetes, urinary tract infection, renal failure, etc., in addition to treatment based on the etiology, the addition of UA-lowering drugs should be considered; metformin, atorvastatin, fenofibrate, Losartan and amlodipine have varying degrees of uric acid-lowering effects while lowering blood sugar, lipids, and blood pressure. They can be used selectively, but they should not be used for a long time

[0014] Hyperuricemia is found by biochemical examination. Although there is no specific record of "hyperuricemia" in traditional Chinese medicine, the "gout" caused by the disease in the middle and late stage is attributed to "arthritis", "calendar", "Beriberi" and other disease categories [Chen LY, Zhu WH, Chen ZW, et al. Relationship between hyperuricemia and metabolic syndrome [J]. JZUS-B, 2007, 8:593-598. - Guo Jing, Wang Shaojie. Asymptomatic high Dietary conditioning of uric acidemia and thoughts on TCM treatment[J]. Journal of Beijing University of Traditional Chinese Medicine, 2010, 33(11):786-788.]