39results about How to "Lower urea nitrogen" patented technology

The invention provides a phellinus igniarius fruit body extract product, and applications thereof in the preparation of drugs for treating chronic renal failure, and belongs to the technical field ofmedicines. A method for preparing the extract product includes the following steps: 1) performing ultrasonic extraction after mixing and soaking phellinus igniarius fruit bodies and an ethanol aqueoussolution so that an extract solution can be obtained; 2) concentrating the extract solution to obtain extract; and 3) performing water dissolution on the extract to mix with chloroform, and performing extraction and concentration so that the phellinus igniarius fruit body extract product can be obtained. The extract product can be used for preparing drugs which can treat chronic renal failure, and is good in treating effect; the extract product can reduce urea nitrogen and serum creatinine, and the reduction of the urea nitrogen and serum creatinine has significantly difference at statistics;and the extract product is small in toxic and side effect and low in cost.

The invention relates to a traditional Chinese medicine composition for treating diabetic nephropathy. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 25-35 parts of astragalus membranaceus, 15-25 parts of cordyceps cicadae, 8-12 parts of taxus chinensis, 1-5 parts of saffron, 10-15 parts of Chinese wolfberry, 10-20 parts of lucid ganoderma, 15-25 parts of radix puerariae, 15-25 parts of gynostemma pentaphylla, 10-20 parts of wine-treated rhubarb and 3-9 parts of liquorice. The invention further provides an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention has a very good protection effect on the kidney of a rat with diabetic nephropathy,and can effectively reduce kidney weight index, blood sugar, serum creatinine and urea nitrogen, reduce proteinuria and improve pathological injury of kidney tissues of the rat with diabetic nephropathy. According to the application disclosed by the invention, the effects of reducing proteinuria and protecting kidneys are achieved by down-regulating the expression of TGF-beta1, p-Smad2, p-Smad3 and alpha-SMA proteins in kidney tissues of DN rats.

The invention provides a marine bioactive polysaccharide or oligosaccharide granular tea drink for improving metabolic syndrome (six highs and one lipid, namely high blood pressure, high blood lipid, high blood sugar, high uricemia, high insulinemia, high body weight and high fatty liver). The marine bioactive polysaccharide or oligosaccharide granular tea drink is prepared by using as a dominant raw material, and blending 0.5-3.0 parts of marine bioactive polysaccharide or oligosaccharide with 0.5-4.0 parts of algae powder, 0.5-1.5 parts of cordyceps militaris, 0.05-0.5 part of bamboo leaves, 0.5-1.5 parts of burdock and 0.5-2.0 parts of corn stigma in parts by weight, wherein the components are uniformly mixed to keep powdery, or granulated and pelleted into the granular tea drink or into tea bags which are brewed or soaked in boiled water for use.

The invention discloses a traditional Chinese medicine for treating chronic nephritis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 45 parts of radix astragali, 15 parts of dangshen, 30 parts of dangshen roots, 15 parts of peach kernels, 15 parts of safflower carthamus, 15 parts of red paeony roots, 10 parts of motherworts, 10 parts of achyranthes bidentata and 10 parts of angelica sinensis. According to the formula, bulk drugs are in compatibility of medicines in a dialectical mode, together with the functions of tonifying the kidney and promoting blood circulation to remove blood stasis, the symptom can be relieved, proteinuria can be eliminated or reduced, and the kidney function is improved, so that the traditional Chinese medicine has the obvious curative effect in patients suffering from chronic nephritis.

The invention discloses a complex Chinese medicine preparation for reinforcing kidney, which is prepared by the following raw materials in parts by weight: 3-8 parts astragalus mongholicus, 6-10 parts Chinese yam, 5-12 parts rehmannia glutinosa libosch, 8-15 parts leech, 7-22 parts cogongrass rhizome, 15-20 parts gorgon fruit, 5-15 parts herba cepbalanoplosis segeti, 3-7 parts fructus rosae laevigatae, 6-20 parts madder, 4-15 parts pseudo-ginseng, 16-33 parts rhizoma nelumbinis, 14-32 parts unpolished rice root, 6-19 parts hairyvein agrimony, 5-15 parts angelica sinensis, 3-10 parts ginseng, and 6-15 parts rhizoma atractylodis macrocephalae. The complex Chinese medicine preparation is taken orally by chronic nephritis patients, so that urea nitrogen can be reduced; proteinuria is reduced; the kidney is reinforced; and the complex Chinese medicine preparation has the efficacies of tonifying spleen, tonifying kidney, inducing astringency, astringing to arrest bleeding and cool blood, and removing heat to promote salivation, and has obvious effects on deficiency of the spleen and kidney, functional metrorrhagia, extravasation of blood, release of sperm of chronic nephritis.

The invention relates to a traditional Chinese medicine preparation for treating diabetic nephropathy and preparation and administration methods thereof. The traditional Chinese medicine preparation is prepared from the following raw materials: astragalus membranaceus, radix pseudostellariae, semen cuscutae, cornus officinalis sieb et zucc, bighead atractylodes rhizome, the root of kudzu vine, gorgon fruit powder, fructus rosae laevigatae powder, periostracum cicada powder, eupatorium powder, agastache rugosus powder, rheum officinale powder, scutellaria baicalensis powder, radix rehmanniae recen, pseudo-ginseng powder and salviae miltiorrhizae. According to the theory of traditional Chinese medicine, treatment determination based on syndrome differentiation is performed by combining features of incidence of diabetic nephropathy and the condition of kidney injury, so that a traditional Chinese medicine compound preparation is formulated; through long-term clinical observation, the clinical symptoms of a patient are improved, proteinuria, urea nitrogen and serum creatinine are decreased to different extents, development of nephropathy is delayed, the renal function is improved, and the preparation plays a role of treating both symptoms and root causes.

The invention relates to a preparation method and application of an oligomeric alginate sulfate ester salt, belonging to the field of raw material preparation of chemicals. The preparation method of the oligomeric alginate sulfate provided by the invention is to add pyridine and chlorosulfonic acid after degradation, emulsification and washing to prepare oligomeric alginate sulfate, and use potassium ions, sodium ions or ammonia water to form a salt, Potassium oligomeric alginate sulfate, sodium oligomeric sodium alginate sulfate or ammonium oligomeric ammonium alginate sulfate are generated. The preparation method provided by the invention overcomes the problems of complex process in the prior art through direct sulfonation, and optimizes the degradation process of alginic acid.

A Chinese medicine for treating chronic nephritis is prepared proportionally from Asiatic pennywort herb, astragalus root and Chuan-xiong rhizome through proportional mixing, adding alcohol solution, reflux extracting, collecting the liquid extract, recovering alcohol, adding deionized water, boiling, cooling and laying aside for 10-24 hrs.

In order to solve the problems that the existing drugs for treating nephropathy are still not ideal in effect for certain cases and high in toxicity of Chinese herb extracts, the invention provides application of triterpene, which is safer and remarkable in curative effect, from poria cocos peel in preparation of medicines for treating the nephropathy; the triterpene from the poria cocos peel is an ethanol extract of the poria cocos peel. The triterpene from the poria cocos peel can reduce the pathologic change degree of the kidney, reduce the content of urinary protein caused by the nephropathy, reduce creatinine and urea nitrogen and play a role in the treatment for the nephropathy.

The present invention belong to the field of Chinese medicine technology, and discloses a Chinese medicine extract and capsule preparation for curing chronic nephritis, renal failure and urinaemia, etc. and their preparation method. Said Chinese medicine extract is made up by using 13 Chinese medicinal materials of astragalus root, American ginseng, poria, ovate atractylodex root, rehmannia flower, cordyceps, eucommia bark, lyceum berry and others through a certain preparation method. Then the obtained extract is placed into the capsule so as to obtain the invented Chinese medicine extract capsule preparation.

The invention discloses TCM composition for treatment of acute renal failure. The TCM composition comprises the raw material medicines of 25-150 g of gypsum, 12-25 g of rhizoma anemarrhenae, 15-30 g of root of rehmannia, 10-25 g of honeysuckle, 10-12 g of radix achyranthis bidentatae, 12-18 g of gardenia jasminoides ellis, 10-18 g of salvia miltiorrhiza, 10-15 g of radix curcumae, 12-18 g of ligusticum wallichii and 10-15 g of root of common peony by weight. According to the invention, years of research and clinical observation of hundreds of patients show that the TCM composition for treatment of acute renal failure has an obvious clinical treatment effect. The positive effect against the renal failure is achieved, and the TCM composition has the curative effects of improving the renal function, reducing urea nitrogen and creatinine, and the like, and has the efficacies of clearing heat, removing toxicity, draining turbidity to save the renal, relieving stagnant qi and cleaning abdominal mass, cooling blood and hemostasis, engendering liquid and dredging collaterals, increasing humor and offensively precipitating, and the like.

The invention relates to the technical field of medicine, provides an active substance for effective treatment from the perspective of traditional Chinese medicine, aiming at the deficiencies in the prior art and in the treatment methods of hyperuricemia, and mainly relates to application of water extract of lance atractylodes rhizomes in treating hyperuricemia. The research of the invention findsthat the water extract of lance atractylodes rhizomes has a good effect on reducing the content of uric acid (UA), urea nitrogen (BUN) and creatinine (SCr) in the body, and has significant effect onrelieving liver atrophy, spleen and lung enlargement and weight loss caused by hyperuricemia, and the research provides a new idea and method for treating hyperuricemia.

The invention relates to application of ergot sterone in the preparation of medicaments for treating chronic renal failure. The ergot sterone has the effects of lowering urea nitrogen and serum creatinine, improving the renal function and reducing the pathological damage of adenine metabolites to the kidney. The invention provides a novel medicament for clinically treating chronic renal failure caused by adenine, aristolochic acid, rhubarb and the like.

The invention discloses a traditional Chinese medicinal preparation used for treating nephritic syndrome. The traditional Chinese medicinal preparation used for treating the nephritic syndrome is prepared from the following raw materials in weight: 20-30g of polygonatum kingianum, 10-20g of gorgon fruit, 10-20g of parasitic loranthus, 10-20g of dried tangerine or orange peel, 10-20g of leonurus japonicus, 10-20g of poria cocos, 10-20g of Chinese yam, 10-20g of schisandra chinensis, 10-20g of hairyvein agrimony, 8-15g of alpinia oxyphylla, 8-12g of raspberry, 8-12g of cortex phellodendri, 8-12g of herba pyrrosiae, 8-12g of mantis eggcase, 8-12g of pulp of cornus and 8-15g of codonopsis pilosula. The traditional Chinese medicinal preparation used for treating the nephritic syndrome has the advantages that compatibility of medicines is excellent, both symptoms and root causes are treated, combination of tonification and purgation is realized, metal is strengthened by reinforcing earth, the effects of strengthening spleen and tonifying kidney, tonifying qi and strengthening exterior, clearing heat and drying dampness as well as alleviating water retention and treating stranguria are realized by the raw materials jointly, and the traditional Chinese medicinal preparation used for treating the nephritic syndrome has the advantages of definite curative effect, low cost, no side effect, high cure rate and low recurrence rate compared with the traditional therapeutic method, so that the traditional Chinese medicinal preparation used for treating the nephritic syndrome is worthy of being clinically popularized and applied.

The invention discloses a traditional Chinese medicinal injection for preventing and treating a chronic Aleutian disease of a mink and a preparation method thereof. The traditional Chinese medicinal injection is prepared from the following components as raw materials: 5-15 parts of aspleniaceae, 8-20 parts of madder, 10-20 parts of berchemia sinica, 10-20 parts of serissa serissoides, 10-20 parts of kochia shoot, 5-15 parts of farfugium japonicum, 6-12 parts of bighead atractylodes rhizome, 10-30 parts of corn stigma, 4-8 parts of fennel, 4-10 parts of lindera aggregata, 10-20 parts of mountain ebony, 6-9 parts of pummelo seed, 10-25 parts of russula virescens, 10-30 parts of ventilago leiocarpa benth, 10-20 parts of argentina anserina, 5-10 parts of argentina anserina, 5-10 parts of lucid ganoderma, 5-15 parts of ginseng, 5-15 parts of polygonum multiflorum and 6-10 parts of liquorice. The traditional Chinese medicinal injection is a pure traditional Chinese medicinal preparation, is non-toxic to the mink and convenient to use, can take effect quickly, has a good therapeutic effect on the chronic Aleutian disease of the mink, can enhance the immunity of the mink, and is conducive to improving economic benefits of a farmer.

The invention discloses a feed additive used for repelling mosquitoes and removing the odor of a pigsty. The feed additive comprises a yucca extract, cinnamyl aldehyde, anise alcohol, allicin, tea polyphenol and a proper quantity of carriers. The raw materials of the feed additive are extracted from green plants, so that the feed additive is green, safe, and free of residue, pollution and poison; added into a pig feed, the feed additive is capable of repelling the mosquitoes, removing the odor and improving the environment of the pigsty, and is also capable of promoting the growth of pigs, improving the carcass quality and improving the immune function of the pigs; the demands of the time on ecological environmental protection and healthful aquaculture in the current livestock husbandry can be met.

The invention discloses a feed additive capable of preventing and treating a chronic aleutian disease of minks and a preparation method of the feed additive. The feed additive is prepared from the following components of enteromorpha, seeds of coral peatree, black sesame seeds, kelp, clamworm powder, fish scales, olive oil, herb of sibirica walking fern, radix rubiae, roots of snow of June, kochia scoparia seedlings, largehead atractylodes rhizomes, corn stigma, fennel fruits, radix linderae, bauhinia variegate roots, bark, leaves and flowers, pummelo seeds, russula virescens, roots or stem of smoothfruit ventilago, roots of silverweed cinquefoil, radix curcumae, ginseng, radix polygoni multiflori and licorice roots. The feed additive disclosed by the invention does not contain antibiotics, is non-toxic and harmless to the minks, and is convenient to use; medicines can exert effects quickly, the feed additive has a good treatment effect on the minks suffering from the chronic aleutian disease, the immunity of the minks is strengthened, and increase of economic benefits of breeding households is facilitated.

The invention discloses a traditional Chinese medicinal preparation used for treating nephritic syndrome. The traditional Chinese medicinal preparation used for treating the nephritic syndrome is prepared from the following raw materials in weight: 20-30g of polygonatum kingianum, 10-20g of gorgon fruit, 10-20g of parasitic loranthus, 10-20g of dried tangerine or orange peel, 10-20g of leonurus japonicus, 10-20g of poria cocos, 10-20g of Chinese yam, 10-20g of schisandra chinensis, 10-20g of hairyvein agrimony, 8-15g of alpinia oxyphylla, 8-12g of raspberry, 8-12g of cortex phellodendri, 8-12g of herba pyrrosiae, 8-12g of mantis eggcase, 8-12g of pulp of cornus and 8-15g of codonopsis pilosula. The traditional Chinese medicinal preparation used for treating the nephritic syndrome has the advantages that compatibility of medicines is excellent, both symptoms and root causes are treated, combination of tonification and purgation is realized, metal is strengthened by reinforcing earth, the effects of strengthening spleen and tonifying kidney, tonifying qi and strengthening exterior, clearing heat and drying dampness as well as alleviating water retention and treating stranguria are realized by the raw materials jointly, and the traditional Chinese medicinal preparation used for treating the nephritic syndrome has the advantages of definite curative effect, low cost, no side effect, high cure rate and low recurrence rate compared with the traditional therapeutic method, so that the traditional Chinese medicinal preparation used for treating the nephritic syndrome is worthy of being clinically popularized and applied.

The invention discloses a Rhizoma Alismatis-containing traditional Chinese medicine for treating chronic nephritis. The Rhizoma Alismatis-containing traditional Chinese medicine is prepared from the following raw materials by weight: 45 parts of Rhizoma Alismatis, 15 parts of Radix Codonopsis, 30 parts of red sage roots, 14 parts of peach seeds, 15 parts of safflower, 15 parts of red peony roots,10 parts of motherwort, 10 parts of achyranthes roots and 10 parts of Chinese angelica roots. The bulk drugs in the prescription are combined together based on syndrome differentiation and exert kidney-tonifying, blood-circulation-activating and blood-stasis-dissipating effect together, so the traditional Chinese medicine can alleviate the symptoms of chronic nephritis, eliminate or reduce proteinuria and improve kidney functions and has substantial curative effect on patients with chronic nephritis.

The invention relates to application of ergot sterone in the preparation of medicaments for treating chronic renal failure. The ergot sterone has the effects of lowering urea nitrogen and serum creatinine, improving the renal function and reducing the pathological damage of adenine metabolites to the kidney. The invention provides a novel medicament for clinically treating chronic renal failure caused by adenine, aristolochic acid, rhubarb and the like.

The invention discloses a traditional Chinese medicine containing Achyranthes bidentata for treating chronic nephritis, which is prepared from the following raw materials in proportion by weight: 45 parts of Achyranthes bidentata, 15 parts of Codonopsis pilosula, 30 parts of salvia miltiorrhiza, peach kernel, safflower and red peony root 15 parts each, 10 parts each of Motherwort, Achyranthes bidentata, and Angelica sinensis. The raw materials in this prescription are compatible through syndrome differentiation, and have the effects of invigorating the kidney and promoting blood circulation and removing blood stasis. It can relieve symptoms, eliminate or reduce proteinuria, and improve kidney function. It has a significant curative effect on patients with chronic nephritis.

The invention discloses a low-protein amino-acid-balanced feed for yellow broiler hens at a laying period and an application of the low-protein amino-acid-balanced feed, and belongs to the field of feeds. Each kilogram of the feed comprises 13-15% of gross protein, DL-methionine, L-threonine, L-lysine monohydrochloride, isoleucine and L-valine monomers are added to maintain amino acid in the feedbalanced, and rest nutrient levels all refer to the recommended level of NY / T 33-2004 hen raising standard. The low-protein amino-acid-balanced feed does not have any negative effects on the production performance, the egg productivity, the egg quality and the incubation performance of the yellow broiler hens and the growing performance of progeny chickens, can effectively reduce the content of urea nitrogen and uric acid in plasma of the yellow broiler hens, and the nitrogen discharge quantity of excrement and urine. Therefore, according to the feed, protein feeds can be saved, nitrogen pollution can be reduced, and besides, normal reproductive performance and egg quality of the yellow broiler hens can be guaranteed.

The invention discloses a blood-regulating and wind-dispelling paste as well as a preparation method and an application thereof. The blood-regulating and wind-dispelling paste is prepared from the following raw materials in parts by weight: 30 parts of sophora flavescens, 30 parts of fineleaf schizonepeta herb, 30 parts of radix saposhnikoviae, 30 parts of cicada slough, 30 parts of Smilax glabra,30 parts of tribulus terrestris, 30 parts of Chinese angelica, 30 parts of radix scrophulariae, 30 parts of Ligusticum wallichii, 30 parts of fructus cnidii, 30 parts of almonds, 30 parts of cortex dictamni, 1000 parts of calcined gypsum, 200 parts of seawater pearls, 1000 parts of talcum powder and 30 parts of borneol. The invention discloses the blood-regulating and wind-dispelling paste and the preparation method and the application thereof. The blood-regulating and wind-dispelling paste improves the skin itch symptom of a patient suffering from maintenance hemodialysis, has a remarkable effect, does not have adverse effects on blood routine examination and liver functions, can reduce urea nitrogen and blood phosphorus, is safe and reliable, and has few adverse reactions of the patient.

The invention discloses a traditional Chinese medicine containing astragalus for treating chronic nephritis, which is prepared from the following raw materials in proportion by weight: 45 parts of astragalus, 15 parts of codonopsis, 30 parts of salvia miltiorrhiza, 15 parts of peach kernel, safflower and red peony 10 parts each of Motherwort, Achyranthes bidentata, and Angelica sinensis. The raw materials in this prescription are combined through syndrome differentiation to play the functions of invigorating the kidney, promoting blood circulation and removing blood stasis, which can relieve symptoms, eliminate or reduce proteinuria, improve renal function, and have a significant curative effect on patients with chronic nephritis.

The invention discloses a radix aconiti lateralis preparata slice containing traditional Chinese medicine for treating chronic nephritis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 45 parts of radix aconiti lateralis preparata slice, 15 parts of radix codonopsis, 30 parts of radix salviae miltiorrhizae, 15 parts of peach kernels, 15 parts of flos carthami, 15 parts of radix paeoniae rubra, 10 parts of herba leonuri, 10 parts of radix achyranthis bidentatae and 10 parts of radix angelicae sinensis. The compound (the traditional Chinese medicine), on the basis of the differential compatibility of the various medicinal raw materials, can take effects of tonifying kidney, promoting blood circulation and removing stasis; and the traditionalChinese medicine can relieve symptom, reduce or eliminate proteinuria and improve renal functions; therefore, an obvious curative effect can be taken on a patient with the chronic nephritis.

The invention discloses a cortex mori radicis containing traditional Chinese medicine for treating chronic nephritis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 45 parts of rcortex mori radicis, 15 parts of radix codonopsis, 30 parts of radix salviae miltiorrhizae, 15 parts of peach kernels, 15 parts of flos carthami, 15 parts of radix paeoniae rubra, 10 parts of herba leonuri, 10 parts of radix achyranthis bidentatae and 10 parts of radix angelicae sinensis. The compound (the traditional Chinese medicine), on the basis of the differentialcompatibility of the various medicinal raw materials, can take effects of tonifying kidney, promoting blood circulation and removing stasis; and the traditional Chinese medicine can relieve symptom,reduce or eliminate proteinuria and improve renal functions; therefore, an obvious curative effect can be taken on a patient with the chronic nephritis.

The invention discloses dulcitol potassium sulfate ester or dulcitol sodium sulfate ester. The dulcitol potassium sulfate ester or dulcitol sodium sulfate ester is prepared according to the steps of firstly generating dulcitol sulfate ester by reacting dulcitol as the raw material and formamide and chlorosulfonic acid which are added inside, and then carrying out neutralization by adding potassium hydroxide or a potassium hydroxide solution to generate dulcitol potassium sulfate ester or dulcitol sodium sulfate ester. The dulcitol potassium sulfate ester or dulcitol sodium sulfate ester has the function of treating chronic renal failure.

The invention discloses a complex Chinese medicine preparation for reinforcing kidney, which is prepared by the following raw materials in parts by weight: 3-8 parts astragalus mongholicus, 6-10 parts Chinese yam, 5-12 parts rehmannia glutinosa libosch, 8-15 parts leech, 7-22 parts cogongrass rhizome, 15-20 parts gorgon fruit, 5-15 parts herba cepbalanoplosis segeti, 3-7 parts fructus rosae laevigatae, 6-20 parts madder, 4-15 parts pseudo-ginseng, 16-33 parts rhizoma nelumbinis, 14-32 parts unpolished rice root, 6-19 parts hairyvein agrimony, 5-15 parts angelica sinensis, 3-10 parts ginseng, and 6-15 parts rhizoma atractylodis macrocephalae. The complex Chinese medicine preparation is taken orally by chronic nephritis patients, so that urea nitrogen can be reduced; proteinuria is reduced; the kidney is reinforced; and the complex Chinese medicine preparation has the efficacies of tonifying spleen, tonifying kidney, inducing astringency, astringing to arrest bleeding and cool blood, and removing heat to promote salivation, and has obvious effects on deficiency of the spleen and kidney, functional metrorrhagia, extravasation of blood, release of sperm of chronic nephritis.

The invention provides a traditional Chinese medicine composition used for treating diabetic nephropathy. The composition is prepared from 5-20 parts of fructus alpinia oxyphylla, 5-20 parts of lindera aggregate, 5-20 parts of red peony root, 5-20 parts of radix trichosanthis, 5-20 parts of rhizoma atractylodis, 8-25 parts of salviae miltiorrhizae and 8-25 parts of poria cocos. The invention further provides a traditional Chinese medicine preparation prepared from the traditional Chinese medicine composition and a preparation method of the preparation. The traditional Chinese medicine composition integrates monarch, minister, assistant and guide and is rigorous in compatibility, the materials supplement one another, and the composition has the functions of warming and invigorating kidney yang and resolving phlegm and promoting blood circulation, has a remarkable effect on improving diabetic nephropathy clinical syndromes, can reduce serum creatinine and urea nitrogen of patients suffering from diabetic nephropathy, has a good kidney protection function and has good application prospects.