Application of water extract of lance atractylodes rhizomes in preparing drugs for preventing, relieving and/or treating hyperuricemia

Abstract

The invention relates to the technical field of medicine, provides an active substance for effective treatment from the perspective of traditional Chinese medicine, aiming at the deficiencies in the prior art and in the treatment methods of hyperuricemia, and mainly relates to application of water extract of lance atractylodes rhizomes in treating hyperuricemia. The research of the invention findsthat the water extract of lance atractylodes rhizomes has a good effect on reducing the content of uric acid (UA), urea nitrogen (BUN) and creatinine (SCr) in the body, and has significant effect onrelieving liver atrophy, spleen and lung enlargement and weight loss caused by hyperuricemia, and the research provides a new idea and method for treating hyperuricemia.

Description

technical field [0001] The invention relates to the technical field of medicine, and mainly relates to the application of the water extract of the traditional Chinese medicine Atractylodes atractylodis in the treatment of hyperuricemia. Background technique [0002] Hyperuricemia (HUA) is a chronic metabolic disease characterized by increased uric acid production and decreased excretion due to purine metabolic disorders. Under a normal purine diet, if the blood uric acid level on an empty stomach is higher than 420 μmol / L for men and higher than 360 μmol / L for women twice on different days, it is called hyperuricemia. This disease tends to precipitate and deposit urate crystals in the body, leading to gout and inducing many major diseases such as myocardial infarction, coronary heart disease, diabetes, hyperlipidemia, metabolic syndrome and chronic kidney disease. [0003] In recent years, with the rapid economic development and great changes in people's eating and living h...

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Problems solved by technology

[0005] It has been reported in the literature that the traditional Chinese medicine Atractylodes atractylodis has the effects of drying dampness and invigorating the spleen, expelling wind and cold, improving eyesight, and eliminating foulness. It can be used to treat rheumatic arthralgia. And achieved good results, but the processing method and specific curative effect of Atractylodes atractylodes are not yet clear, the relevant research lacks the microscopic analysis of the effective substances, and there is no relevant report about the water extract of Atractylodes atractylodes used alone for the treatment of hyperuricemia , thus resulting in limited curative effect of the compound on hyperuricemia, and there are certain individual differences

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