Composite antibacterial peptide and preparation method thereof as well as bee venom conditioning ointment capable of rapidly relieving pain and preparation method of bee venom conditioning ointment

A compound antibacterial and bee venom technology, which is applied in the direction of non-central analgesics, antibacterial drugs, ointment delivery, etc., can solve the problems that people who are allergic to bee venom cannot accept bee therapy and are difficult to control, so as to shorten the production cycle and promote Tissue healing, good pain relief effect

Active Publication Date: 2021-11-05
广东日和堂医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the effect is quick, it is difficult to control the direct use of bee stings instead of acupuncture, and the bee venom injected through live bee stings contains a large number of allergens, which will make people who are allergic to bee venom unacceptable to bee therapy

Method used

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  • Composite antibacterial peptide and preparation method thereof as well as bee venom conditioning ointment capable of rapidly relieving pain and preparation method of bee venom conditioning ointment
  • Composite antibacterial peptide and preparation method thereof as well as bee venom conditioning ointment capable of rapidly relieving pain and preparation method of bee venom conditioning ointment
  • Composite antibacterial peptide and preparation method thereof as well as bee venom conditioning ointment capable of rapidly relieving pain and preparation method of bee venom conditioning ointment

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0068] The raw material sources of the extracts and polymers in the preparation examples and examples disclosed in Table 1 are to fully disclose to support the specific schemes of the preparation examples and examples of the application, but the technical solutions of the application are not limited to those listed in Table 1. source of raw materials, the raw materials of other manufacturers can be used to realize the technical solution of the present application.

[0069] Table 1

[0070]

[0071]

[0072] Preparation example of compound antimicrobial peptide

preparation example 1

[0074] This preparation example discloses a compound antibacterial peptide, which is prepared by the following steps:

[0075] Step 1), put 150g of honeysuckle extract, 30g of dandelion extract, 50g of licorice extract, 10g of grain worm extract and 660g of edible oil into the medicine pot and stir evenly, boil at 100°C for 2 hours, and filter at room temperature Stand still for 24h to obtain raw material oil.

[0076] Step 2), pour the raw material oil into a homogenizer, add 100g of honey and 0.2g of bee venom extract, heat and homogenize at a temperature of 50°C, make it evenly mixed, let it stand at room temperature for 24 hours, and repeat heating for homogenization , Standing at room temperature for 2 consecutive days to obtain compound antibacterial peptides.

preparation example 2

[0078] This preparation example discloses a compound antibacterial peptide, which is prepared by the following steps:

[0079] Step 1), put 30g of honeysuckle extract, 150g of dandelion extract, 200g of licorice extract, 100g of grain worm extract and 220g of edible oil into a medicine pot and stir evenly, boil at 120°C for 3 hours, and filter at room temperature Stand still for 26h to obtain raw material oil.

[0080] Step 2), pour the raw material oil into a homogenizer, add 300g of honey and 0.7g of bee venom extract, heat and homogenize at a temperature of 60°C, make it evenly mixed, let it stand at room temperature for 26 hours, and repeat heating to homogenize , Standing at room temperature for 3 consecutive days to obtain compound antibacterial peptides.

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PUM

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Abstract

The invention discloses a composite antibacterial peptide and a preparation method thereof as well as a bee venom conditioning ointment capable of rapidly relieving pain and a preparation method of the bee venom conditioning ointment. The composite antibacterial peptide is prepared by adding a honeysuckle extract, a dandelion extract, a licorice extract, honey, a maggot extract and a bee venom extract into edible oil according to a ratio and decocting. The composite antibacterial peptide has the effects of rapidly relieving the pain, promoting tissue healing and being not prone to allergy. In order to make the composite antibacterial peptide better penetrate through the epidermis to permeate into a bone layer and be convenient to use, the composite antibacterial peptide is made into ointment, namely the bee venom conditioning ointment capable of rapidly relieving the pain, so that the composite antibacterial peptide more rapidly permeates into the skin and acts on a affected part, and a better permeation assisting effect is achieved. According to the preparation method of the bee venom conditioning ointment capable of rapidly relieving the pain, a water phase, an oil phase and a mixed phase are separately emulsified and homogenized, and materials can be prepared during production, so that the production period is greatly shortened, and high-efficiency industrial production can be promoted.

Description

technical field [0001] The invention relates to the field of medical devices for external use, in particular to a compound bacteriostatic peptide and its preparation method, and a rapid pain-relieving bee venom conditioning ointment and its preparation method. Background technique [0002] Frozen shoulder, cervical spondylosis, tenosynovitis, arthritis, sciatica, or muscle soreness, stiffness, and bruises caused by exercise have a wide range of people. The elderly are inconvenient to move because of this "chronic disease", and the young people will also accumulate diseases due to work reasons, for example: long-term typing is prone to tenosynovitis, sciatica caused by sedentary, cervical spondylosis, frozen shoulder and other diseases. And this kind of disease is getting younger and younger, it is likely to induce other diseases, and when it is serious, it will affect normal life and work, and bring a great threat to human health. [0003] At present, the quicker pain relie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/17A61K9/06A61K47/34A61K47/44A61P19/02A61P19/08A61P29/00A61P25/02A61P31/04A61K38/02A61K35/644A61K35/64A61K36/484A61K36/9068A61K31/4166A61K31/085A61K31/045
CPCA61K35/644A61K36/484A61K36/355A61K36/288A61K35/64A61K38/1767A61K38/02A61K36/236A61K36/54A61K36/185A61K31/4166A61K36/258A61K31/085A61K36/21A61K36/9068A61K31/045A61K9/06A61K9/0014A61K47/34A61K47/44A61P19/02A61P19/08A61P29/00A61P25/02A61P31/04A61K2236/35A61K2236/53A61K2300/00
Inventor 陈日和包海玲唐飞
Owner 广东日和堂医药科技有限公司
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