New application of penicillin G sodium salt
A penicillin and new-purpose technology, applied in the application field of pharmaceutical compositions or preparations, can solve problems such as family and social economic burden, unsure of clinical efficacy, decreased working ability, etc., to improve blood supply, inhibit platelet aggregation, and prevent thrombosis. effect
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Embodiment 1
[0025] Patient Jiang Moumou, female, 61 years old, came to the clinic because of swelling and pain in fingers, toes and joints of limbs for more than 1 year, which aggravated for 1 month. The history of the present illness suggested that the patient had a sudden chill one day a year ago, and had a high fever of 39.6°C in the afternoon. After sweating profusely, he felt soreness and discomfort in his fingers and toes. The next day, he developed morning stiffness in his hands. The morning stiffness of the fingers disappeared, and after February, it aggravated to more than 1 hour a day, and the swelling and pain gradually increased in the fingers and toes, especially the swelling and pain of the metacarpophalangeal joints and proximal interphalangeal joints of both hands, which has lasted for more than half a year time. In the past 1 month, the condition has worsened, the swelling and pain have increased significantly, and a swelling has grown on the left toe, which is not painfu...
Embodiment 2
[0030] Patient Yin Moumou, female, 61 years old, suffered from pain all over the body, especially in both knee joints. Physical examination on admission: listlessness, 5 mung bean-sized nodules were found on the back of both hands, hard and painless when pressed, all small joints of the hands were deformed: the proximal interphalangeal joints were fusiform and swollen, both wrists were radially oriented Lateral rotation, deviation, ulnar deviation of fingers and palms, severe flexion of proximal interphalangeal joints, hyperextension of distal interphalangeal joints showing "buttonhole flower" deformity and more than 4 groups, proximal interphalangeal joints of multiple fingers Changes in the shape of a "shuttle", with dislocation or subluxation of multiple toe joints, and the toes are basically arranged irregularly overlapping up and down, especially the knee joints are highly swollen, and the skin on the knees is almost cracked and translucent. The buckling deformity has bee...
Embodiment 3
[0037] Patient Wang Moumou, female, 41 years old, did not dare to move for two years due to morning stiffness, swelling and pain of multiple joints in both hands, joint deformation of fingers, both wrists were unable to move due to severe pain, her hands were weak, and she could not even hold a job None, often dropped bowls and chopsticks, asked patients to help with cooking when hospitalized. The patient has great psychological pressure, poor appetite, and eats less and less food. He only eats half a meal per meal and does not eat vegetables. Before joining the hospital, he was diagnosed with rheumatoid arthritis many times in the local hospital.
[0038] Physical examination shows: middle-aged female, thin, poor nutrition, symmetrical index finger, middle finger and ring finger proximal knuckles of both hands are "spindle-shaped". The interval is vague, the patient has standard morning stiffness (the duration of morning stiffness is more than 60 minutes per day, and the dura...
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